Development Level

Tbio 29 | 11,445
Tchem 5 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 6 | 979
impaired glucose tolerance 3 | 75
decreased circulating serum al... 2 | 82
decreased lean body mass 2 | 135
increased lean body mass 2 | 172
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal gait 1 | 69
abnormal iris morphology 1 | 13
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased circulating calcium ... 1 | 36
decreased circulating iron lev... 1 | 32
decreased grip strength 1 | 116
decreased mean platelet volume 1 | 25
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating glucose ... 1 | 24
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased mean platelet volume 1 | 45
increased neutrophil cell numb... 1 | 46
irregularly shaped pupil 1 | 7
limb grasping 1 | 41
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

Carcinoma 24 | 11,493
ovarian cancer 19 | 8,520
osteosarcoma 18 | 7,950
atypical teratoid / rhabdoid tumor 15 | 5,112
lung cancer 14 | 4,740
glioblastoma 13 | 5,792
medulloblastoma, large-cell 13 | 6,241
Cancer 12 | 2,499
ependymoma 12 | 4,679
psoriasis 11 | 6,694
Astrocytoma, Pilocytic 10 | 3,081
Breast cancer 10 | 3,578
adult high grade glioma 10 | 3,801
oligodendroglioma 10 | 2,850
group 3 medulloblastoma 9 | 4,104
group 4 medulloblastoma 9 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
invasive ductal carcinoma 8 | 2,951
lung adenocarcinoma 8 | 2,716
pancreatic cancer 7 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Atopic dermatitis 6 | 952
Pick disease 6 | 1,894
astrocytic glioma 6 | 2,597
colon cancer 6 | 1,478
ductal carcinoma in situ 6 | 1,745
interstitial cystitis 6 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
lung carcinoma 6 | 2,843
malignant mesothelioma 6 | 3,232
non-small cell lung cancer 6 | 2,890
primitive neuroectodermal tumor 6 | 3,035
Cleft Palate 5 | 271
Kidney cancer 5 | 2,613
Rheumatoid arthritis 5 | 1,191
astrocytoma 5 | 1,146
spina bifida 5 | 1,074
Multiple myeloma 4 | 1,332
Osteoporosis 4 | 363
active Crohn's disease 4 | 922
cutaneous lupus erythematosus 4 | 1,057
Breast Neoplasms 3 | 445
Intellectual disability 3 | 1,016
Kidney disease 3 | 430
Liver cancer 3 | 604
Mammary Neoplasms 3 | 425
Polycystic ovary syndrome 3 | 360
Schizophrenia 3 | 1,160
aldosterone-producing adenoma 3 | 665
cystic fibrosis 3 | 1,696
diabetes mellitus 3 | 1,728
esophageal adenocarcinoma 3 | 737
juvenile dermatomyositis 3 | 1,187
non primary Sjogren syndrome sicca 3 | 891
pituitary cancer 3 | 1,972
progressive supranuclear palsy 3 | 676
ulcerative colitis 3 | 1,819
Alobar Holoprosencephaly 2 | 14
Alzheimer's disease 2 | 658
Amyotrophic lateral sclerosis 2 | 451
Asthma 2 | 385
Autosomal recessive predisposition 2 | 1,442
Bilateral fifth finger clinodactyly 2 | 110
Bipolar Disorder 2 | 666
Cognitive delay 2 | 608
Crohn's disease 2 | 321
Curvature of little finger 2 | 110
Dull intelligence 2 | 645
Endometriosis 2 | 540
Epilepsy 2 | 792
Eye Abnormalities 2 | 35
Fetal Growth Retardation 2 | 189
Global developmental delay 2 | 608
Holoprosencephaly 2 | 56
Infant, Small for Gestational Age 2 | 176
Intrauterine retardation 2 | 176
Lobar Holoprosencephaly 2 | 20
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Microphthalmos 2 | 100
Myopia 2 | 176
Poor school performance 2 | 645
Seizures 2 | 596
Semilobar Holoprosencephaly 2 | 14
Short stature 2 | 531
Small head 2 | 374
Waldenstrons macroglobulinemia 2 | 765
active ulcerative colitis 2 | 764
acute myeloid leukemia 2 | 783
acute quadriplegic myopathy 2 | 1,158
breast carcinoma 2 | 1,638
dermatomyositis 2 | 966
medulloblastoma 2 | 720
nasopharyngeal carcinoma 2 | 1,058
primary pancreatic ductal adenocarcinoma 2 | 1,109
sonic hedgehog group medulloblastoma 2 | 467
tuberculosis 2 | 2,010

Tissue

Endocrine System 36 | 18,159
Digestive Tract 35 | 17,369
Female tissues 35 | 17,400
Male tissues 35 | 17,142
Skin and soft tissues 35 | 17,230
Liver and Pancreas 34 | 16,750
Respiratory system 34 | 16,393
Urinary Tract 34 | 16,678
Blood and immune system 33 | 16,909
Cardiovascular System 32 | 15,192
Nervous System 32 | 16,725

Target Family

Non-IDG 21 | 12,091
Enzyme 10 | 4,145
Transcription Factor 3 | 1,400
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

GO Process

embryo development 36 | 36
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Rapamycin-insensitive companion of mTOR RICTOR Tbio Non-IDG -2.79454 597.0 440
MyoD family inhibitor MDFI Tbio Non-IDG -1.71031 47.9 104
G/T mismatch-specific thymine DNA glycosylase TDG Tbio Enzyme -2.46252 297.6 225
Alpha-(1,3)-fucosyltransferase 10 FUT10 Tdark Enzyme -0.25307 1.95 121
Ras-related protein Rab-14 RAB14 Tbio Enzyme -1.47825 30.5 103
Pancreas transcription factor 1 subunit alpha PTF1A Tbio Transcription Factor -2.60800 401.4 317
Ubiquitin carboxyl-terminal hydrolase 22 USP22 Tbio Enzyme -1.68483 57.9 220
CUGBP Elav-like family member 4 CELF4 Tbio Non-IDG -1.58928 38.2 56
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.65728 4647.9 684
E3 ubiquitin-protein ligase UBR3 UBR3 Tbio Enzyme -0.89502 8.28 22