Development Level

Tbio 21 | 11,445
Tchem 1 | 1,598

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal behavior 3 | 298
decreased bone mineral density 3 | 126
abnormal bone structure 2 | 187
abnormal retina morphology 2 | 71
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased circulating triglyce... 2 | 79
hyperactivity 2 | 148
short tibia 2 | 97
abnormal lung morphology 1 | 26
abnormal motor capabilities-co... 1 | 5
abnormal response to new envir... 1 | 10
abnormal response to tactile s... 1 | 17
abnormal sleep behavior 1 | 70
alopecia 1 | 1
cataract 1 | 92
decreased IgE level 1 | 6
decreased body length 1 | 101
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased grip strength 1 | 116
decreased mean corpuscular hem... 1 | 50
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased heart weight 1 | 62
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
tremors 1 | 39
trunk curl 1 | 16

Disease

Carcinoma 14 | 11,493
ovarian cancer 12 | 8,520
osteosarcoma 10 | 7,950
medulloblastoma, large-cell 9 | 6,241
glioblastoma 8 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
lung cancer 6 | 4,740
Astrocytoma, Pilocytic 5 | 3,081
ependymoma 5 | 4,679
Breast cancer 4 | 3,578
Cancer 4 | 2,499
Kidney cancer 4 | 2,613
adult high grade glioma 4 | 3,801
atypical teratoid / rhabdoid tumor 4 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
invasive ductal carcinoma 4 | 2,951
oligodendroglioma 4 | 2,850
spina bifida 4 | 1,074
subependymal giant cell astrocytoma 4 | 2,287
Amyotrophic lateral sclerosis 3 | 451
acute quadriplegic myopathy 3 | 1,158
aldosterone-producing adenoma 3 | 665
astrocytic glioma 3 | 2,597
interstitial cystitis 3 | 2,312
medulloblastoma 3 | 720
pediatric high grade glioma 3 | 1,064
primitive neuroectodermal tumor 3 | 3,035
psoriasis 3 | 6,694
Attention deficit hyperactivity disorder 2 | 278
Charcot-Marie-Tooth disease type 2B 2 | 6
Gaucher disease type 1 2 | 180
Lateral sclerosis 2 | 15
Myocardial Ischemia 2 | 169
Neurodegenerative disease 2 | 414
Schizophrenia 2 | 1,160
Usher syndrome type 1 2 | 10
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
group 3 medulloblastoma 2 | 4,104
group 4 medulloblastoma 2 | 1,855
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primary pancreatic ductal adenocarcinoma 2 | 1,109
Absent reflex 1 | 92
Absent tendon reflex 1 | 92
Acquired flat foot 1 | 72
Alzheimer's disease 1 | 658
Cardiovascular system disease 1 | 246
Centronuclear myopathy 1 | 27
Charcot-Marie-Tooth disease 1 | 62
Colonic Neoplasms 1 | 142
Congenital pes cavus 1 | 88
Decreased motor NCV 1 | 22
Decreased number of large and small myelinated fibers 1 | 20
Decreased tendon reflex 1 | 122
Distal amyotrophy 1 | 51
Distal limb muscle weakness due to peripheral neuropathy 1 | 62
Distal muscle weakness 1 | 62
Flatfoot 1 | 73
Heart disease 1 | 306
Hermansky-Pudlak syndrome 1 | 42
Lewy Body Disease 1 | 21
Liver Cirrhosis, Experimental 1 | 769
Liver disease 1 | 237
Lung Neoplasms 1 | 232
Lysosomal storage disease 1 | 10
Male infertility 1 | 206
Multiple Sclerosis 1 | 540
Myocardial Infarction 1 | 151
Neuronal ceroid lipofuscinosis 8 northern epilepsy variant 1 | 6
Neuropathy 1 | 261
Oculocerebrorenal syndrome 1 | 29
Paraplegia 1 | 74
Polycystic ovary syndrome 1 | 360
Pontocerebellar hypoplasia 1 | 36
Prostate cancer 1 | 175
Reflex, Deep Tendon, Absent 1 | 92
Retinitis pigmentosa 11 1 | 59
Status Epilepticus 1 | 98
Toxic encephalopathy 1 | 141
Visual epilepsy 1 | 4
Waldenstrons macroglobulinemia 1 | 765
active ulcerative colitis 1 | 764
chronic lymphosyte leukemia 1 | 204
colon cancer 1 | 1,478
fibroadenoma 1 | 559
head and neck cancer 1 | 271
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
hereditary spastic paraplegia 1 | 318
nasopharyngeal carcinoma 1 | 1,058
posterior fossa group A ependymoma 1 | 468
tuberculosis 1 | 2,010
tuberculosis and treatment for 6 months 1 | 409
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 21 | 16,909
Cardiovascular System 21 | 15,192
Digestive Tract 21 | 17,369
Endocrine System 21 | 18,159
Female tissues 21 | 17,400
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Nervous System 21 | 16,725
Respiratory system 21 | 16,393
Skin and soft tissues 21 | 17,230
Urinary Tract 21 | 16,678

Target Family

Non-IDG 17 | 12,091
Enzyme 3 | 4,145
Kinase 2 | 634

GO Process

early endosome to late endosom... 22 | 22
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
WD repeat-containing protein 91 WDR91 Tbio Non-IDG -0.72903 5.46 54
Protein Hook homolog 1 HOOK1 Tbio Non-IDG -1.16190 13.1 187
Epithelial membrane protein 2 EMP2 Tbio Non-IDG -2.30856 210.6 116
Ankyrin repeat domain-containing protein 27 ANKRD27 Tbio Non-IDG -1.12548 14.6 65
Serine/threonine-protein kinase LMTK2 LMTK2 Tbio Kinase -1.46351 31.6 189
Ras-related protein Rab-7a RAB7A Tbio Enzyme -2.66545 435.4 248
Syntaxin-8 STX8 Tbio Non-IDG -2.59234 391.5 134
WD repeat-containing protein 81 WDR81 Tbio Non-IDG -1.27329 20.6 5
Putative WAS protein family homolog 3 WASH3P Tbio Non-IDG -0.28297 2.17 0
Tyrosine-protein phosphatase non-receptor type 23 PTPN23 Tbio Enzyme -1.41527 29.6 103