Development Level

Tbio 8 | 11,445

IMPC Phenotype

decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
increased mean platelet volume 1 | 45
increased red blood cell distr... 1 | 34
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 6 | 11,493
glioblastoma 4 | 5,792
ovarian cancer 4 | 8,520
Breast cancer 3 | 3,578
Kidney cancer 3 | 2,613
Pick disease 3 | 1,894
atypical teratoid / rhabdoid tumor 3 | 5,112
osteosarcoma 3 | 7,950
Waldenstrons macroglobulinemia 2 | 765
adult high grade glioma 2 | 3,801
diabetes mellitus 2 | 1,728
lung cancer 2 | 4,740
medulloblastoma, large-cell 2 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
Alzheimer's disease 1 | 658
Arsenic Poisoning 1 | 62
Arterial tortuosity syndrome 1 | 7
Astrocytoma, Pilocytic 1 | 3,081
Autosomal recessive nonsyndromic deafness 2 1 | 5
Autosomal recessive nonsyndromic deafness 63 1 | 10
Autosomal recessive nonsyndromic deafness 7 1 | 7
Batten disease 1 | 13
COPD 1 | 118
Chronic Lymphocytic Leukemia 1 | 262
Cranial nerve palsy 1 | 4
Dermatologic disorders 1 | 93
Down syndrome 1 | 499
Griscelli syndrome 1 | 24
Hemolytic anemia 1 | 77
Holoprosencephaly 1 | 56
Hypertrophy of breast 1 | 17
Legionnaires' disease 1 | 20
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid, Acute 1 | 105
Major Depressive Disorder 1 | 301
Multiple myeloma 1 | 1,332
Neuronal ceroid lipofuscinosis 10 1 | 4
Oculocerebrorenal syndrome 1 | 29
Oculocutaneous albinism 1 | 29
Pancreatic agenesis 1 | 17
Rheumatoid arthritis 1 | 1,191
Skin Diseases 1 | 71
Tetralogy of Fallot 1 | 63
Unipolar Depression 1 | 250
adrenocortical carcinoma 1 | 1,428
astrocytic glioma 1 | 2,597
breast carcinoma 1 | 1,638
ductal carcinoma in situ 1 | 1,745
eosinophilia-myalgia syndrome 1 | 6
ependymoma 1 | 4,679
esophageal adenocarcinoma 1 | 737
group 3 medulloblastoma 1 | 4,104
hand, foot and mouth disease 1 | 13
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
invasive ductal carcinoma 1 | 2,951
juvenile dermatomyositis 1 | 1,187
lung adenocarcinoma 1 | 2,716
malignant mesothelioma 1 | 3,232
non-small cell lung cancer 1 | 2,890
oligodendroglioma 1 | 2,850
primitive neuroectodermal tumor 1 | 3,035
progressive myoclonus epilepsy 1 | 12
psoriasis 1 | 6,694
spina bifida 1 | 1,074
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis 1 | 2,010
tuberculosis and treatment for 6 months 1 | 409
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Non-IDG 7 | 12,091
Enzyme 1 | 4,145

GO Process

early endosome to Golgi transp... 8 | 8
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras-related protein Rab-6A RAB6A Tbio Enzyme -2.09488 134.5 207
Sorting nexin-1 SNX1 Tbio Non-IDG -1.59343 43.7 285
Sorting nexin-8 SNX8 Tbio Non-IDG -1.38931 25.5 152
EH domain-containing protein 3 EHD3 Tbio Non-IDG -1.69661 55.8 89
Trafficking protein particle complex subunit 10 TRAPPC10 Tbio Non-IDG -1.33531 17.3 95
Sorting nexin-2 SNX2 Tbio Non-IDG -1.24500 17.2 141
Rabenosyn-5 RBSN Tbio Non-IDG -2.24474 148.4 121
Syntaxin-5 STX5 Tbio Non-IDG -1.88347 75.4 123