Development Level

Tbio 42 | 11,445
Tchem 5 | 1,598
Tdark 2 | 6,588
Tclin 1 | 613

IMPC Phenotype

abnormal bone mineralization 1 | 38
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal seminal vesicle morph... 1 | 114
abnormal vertebrae morphology 1 | 18
corneal opacity 1 | 32
decreased body weight 1 | 161
decreased circulating glycerol... 1 | 16
decreased red blood cell distr... 1 | 41
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
increased bone mineral density 1 | 72
increased circulating triglyce... 1 | 42
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased startle reflex 1 | 112
male infertility 1 | 123
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
small testis 1 | 58
thrombocytosis 1 | 27
tremors 1 | 39

Disease

Carcinoma 35 | 11,493
osteosarcoma 32 | 7,950
ovarian cancer 30 | 8,520
Cancer 26 | 2,499
lung cancer 20 | 4,740
group 3 medulloblastoma 19 | 4,104
glioblastoma 16 | 5,792
medulloblastoma, large-cell 16 | 6,241
psoriasis 16 | 6,694
Breast cancer 15 | 3,578
malignant mesothelioma 15 | 3,232
ependymoma 14 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
atypical teratoid / rhabdoid tumor 13 | 5,112
Ataxia telangiectasia 11 | 34
Nijmegen breakage syndrome 11 | 24
Kidney cancer 10 | 2,613
Autosomal recessive predisposition 9 | 1,442
Pick disease 9 | 1,894
Short stature 9 | 531
astrocytic glioma 9 | 2,597
breast carcinoma 9 | 1,638
Chromosome Breakage 8 | 36
Fanconi anemia 8 | 56
Intellectual disability 8 | 1,016
Small head 8 | 374
adult high grade glioma 8 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
oligodendroglioma 8 | 2,850
primitive neuroectodermal tumor 8 | 3,035
Cognitive delay 7 | 608
Dull intelligence 7 | 645
Global developmental delay 7 | 608
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental and motor retardation 7 | 608
Mental deficiency 7 | 645
Microcephaly 7 | 166
Poor school performance 7 | 645
Severe combined immunodeficiency 7 | 51
Xeroderma pigmentosum 7 | 43
invasive ductal carcinoma 7 | 2,951
non-small cell lung cancer 7 | 2,890
Hypoplastic mandible condyle 6 | 275
Increased chromosomal breakage 6 | 27
Mandibular hypoplasia 6 | 275
Micrognathism 6 | 275
Multiple myeloma 6 | 1,332
Prostatic Neoplasms 6 | 495
Schizophrenia 6 | 1,160
Waldenstrons macroglobulinemia 6 | 765
Werner syndrome 6 | 29
adrenocortical carcinoma 6 | 1,428
colon cancer 6 | 1,478
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Breast Neoplasms 5 | 445
Cryptorchidism 5 | 296
DNA ligase IV deficiency 5 | 7
Epilepsy 5 | 792
Fetal Growth Retardation 5 | 189
Hereditary Breast and Ovarian Cancer Syndrome 5 | 14
Infant, Small for Gestational Age 5 | 176
Intrauterine retardation 5 | 176
Mammary Neoplasms 5 | 425
Photosensitivity of skin 5 | 51
Seizures 5 | 596
Stomach Neoplasms 5 | 300
diabetes mellitus 5 | 1,728
ductal carcinoma in situ 5 | 1,745
lung adenocarcinoma 5 | 2,716
pancreatic cancer 5 | 2,398
pituitary cancer 5 | 1,972
subependymal giant cell astrocytoma 5 | 2,287
ulcerative colitis 5 | 1,819
Astrocytoma, Pilocytic 4 | 3,081
Attention deficit hyperactivity disorder 4 | 278
Broad flat nasal bridge 4 | 236
Cerebellar Ataxia 4 | 304
Congenital deafness 4 | 185
Deafness 4 | 198
Erythema 4 | 58
Hearing Loss, Partial 4 | 185
Lymphoma 4 | 81
Muscle Spasticity 4 | 195
Muscle hypotonia 4 | 571
Nasal bridge wide 4 | 236
Nystagmus 4 | 317
Strabismus 4 | 270
astrocytoma 4 | 1,146
gastric carcinoma 4 | 807
hearing impairment 4 | 199
hepatocellular carcinoma 4 | 547
lung carcinoma 4 | 2,843
nasopharyngeal carcinoma 4 | 1,058
non primary Sjogren syndrome sicca 4 | 891
tuberculosis 4 | 2,010
acute quadriplegic myopathy 3 | 1,158
dermatomyositis 3 | 966
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
pancreatic carcinoma 3 | 562

Tissue

Blood and immune system 50 | 16,909
Cardiovascular System 50 | 15,192
Digestive Tract 50 | 17,369
Endocrine System 50 | 18,159
Female tissues 50 | 17,400
Liver and Pancreas 50 | 16,750
Male tissues 50 | 17,142
Nervous System 50 | 16,725
Respiratory system 50 | 16,393
Skin and soft tissues 50 | 17,230
Urinary Tract 50 | 16,678

Target Family

Non-IDG 30 | 12,091
Enzyme 12 | 4,145
Epigenetic 4 | 242
Kinase 2 | 634
TF/Epigenetic 1 | 38
Transcription Factor 1 | 1,400

GO Process

double-strand break repair via... 50 | 50
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein PAXX PAXX Tbio Non-IDG -1.45074 28.1 33
Lysine-specific demethylase 2A KDM2A Tchem Epigenetic -1.51861 36.3 183
TP53-binding protein 1 TP53BP1 Tbio Epigenetic -2.69485 464.8 577
E3 ubiquitin-protein ligase RNF8 RNF8 Tbio Enzyme -1.80196 70.0 250
Cell cycle regulator of non-homologous end joining C7orf49 Tdark Non-IDG -1.76455 54.4 25
DNA ligase 4 LIG4 Tbio Enzyme -2.14909 140.9 204
Telomere-associated protein RIF1 RIF1 Tbio Non-IDG -0.03141 1.27 98
26S proteasome non-ATPase regulatory subunit 14 PSMD14 Tbio Enzyme -1.80255 64.2 195
Histone-lysine N-methyltransferase NSD2 NSD2 Tbio TF/Epigenetic -2.43336 275.2 123
Histone H3.1t HIST3H3 Tbio Non-IDG -1.05426 10.9 1265