Development Level

Tbio 22 | 11,445
Tchem 3 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal bone structure 3 | 187
increased heart weight 3 | 62
increased startle reflex 3 | 112
preweaning lethality, complete... 2 | 979
abnormal craniofacial morpholo... 1 | 33
abnormal eye morphology 1 | 68
abnormal hindbrain morphology 1 | 10
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal seminal vesicle morph... 1 | 114
cataract 1 | 92
decreased lymphocyte cell numb... 1 | 83
edema 1 | 59
hydrometra 1 | 53
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased neutrophil cell numb... 1 | 46
increased total body fat amoun... 1 | 134
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56

Disease

Carcinoma 19 | 11,493
osteosarcoma 17 | 7,950
ovarian cancer 16 | 8,520
Cancer 14 | 2,499
psoriasis 14 | 6,694
pancreatic cancer 13 | 2,398
atypical teratoid / rhabdoid tumor 12 | 5,112
lung cancer 12 | 4,740
medulloblastoma, large-cell 12 | 6,241
Breast cancer 10 | 3,578
glioblastoma 10 | 5,792
interstitial cystitis 9 | 2,312
invasive ductal carcinoma 9 | 2,951
Kidney cancer 8 | 2,613
ependymoma 8 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
pituitary cancer 8 | 1,972
Astrocytoma, Pilocytic 7 | 3,081
Cryptorchidism 7 | 296
Epilepsy 7 | 792
Intellectual disability 7 | 1,016
Seizures 7 | 596
breast carcinoma 7 | 1,638
ductal carcinoma in situ 7 | 1,745
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
oligodendroglioma 7 | 2,850
Craniofacial Abnormalities 6 | 151
Short stature 6 | 531
adult high grade glioma 6 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
Adenoma 5 | 167
Concave bridge of nose 5 | 195
Congenital hypoplasia of penis 5 | 176
Depressed nasal bridge 5 | 195
Depressed nasal root/bridge 5 | 195
Dull intelligence 5 | 645
Hypoparathyroidism 5 | 41
Kidney disease 5 | 430
Liver cancer 5 | 604
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Poor school performance 5 | 645
Small head 5 | 374
malignant mesothelioma 5 | 3,232
Anemia 4 | 365
Atopic dermatitis 4 | 952
Biliary tract cancer 4 | 19
Brachydactyly 4 | 156
Cleft Lip 4 | 141
Failure to gain weight 4 | 365
Fetal Growth Retardation 4 | 189
Fibrodysplasia ossificans progressiva 4 | 17
Infant, Small for Gestational Age 4 | 176
Intrauterine retardation 4 | 176
Obesity 4 | 678
Orbital separation excessive 4 | 244
Pediatric failure to thrive 4 | 365
Polycystic ovary syndrome 4 | 360
Sensorineural Hearing Loss (disorder) 4 | 284
Stomach cancer 4 | 30
Thyroid cancer 4 | 36
acute quadriplegic myopathy 4 | 1,158
adrenocortical carcinoma 4 | 1,428
group 4 medulloblastoma 4 | 1,855
pediatric high grade glioma 4 | 1,064
primitive neuroectodermal tumor 4 | 3,035
substance-related disorder 4 | 162
tuberculosis 4 | 2,010
Acromegaly 3 | 51
Bipolar Disorder 3 | 666
Congenital deafness 3 | 185
Cushing's syndrome 3 | 48
Deafness 3 | 198
Endometriosis 3 | 540
Hearing Loss, Partial 3 | 185
Hemoglobin low 3 | 124
Highly variable clinical phenotype 3 | 150
Highly variable phenotype and severity 3 | 150
Highly variable phenotype, even within families 3 | 150
Highly variable severity 3 | 157
Holoprosencephaly 3 | 56
Hypothyroidism 3 | 122
Isolated cases 3 | 72
Phenotypic variability 3 | 150
Pituitary adenoma 3 | 38
Pneumonia 3 | 174
Schizophrenia 3 | 1,160
Stomach Neoplasms 3 | 300
Variable expressivity 3 | 157
astrocytoma 3 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
cystic fibrosis 3 | 1,696
diabetes mellitus 3 | 1,728
fibroadenoma 3 | 559
hearing impairment 3 | 199
lung adenocarcinoma 3 | 2,716
primary pancreatic ductal adenocarcinoma 3 | 1,109
subependymal giant cell astrocytoma 3 | 2,287

Tissue

Endocrine System 24 | 18,159
Female tissues 24 | 17,400
Male tissues 24 | 17,142
Skin and soft tissues 24 | 17,230
Blood and immune system 23 | 16,909
Digestive Tract 23 | 17,369
Urinary Tract 23 | 16,678
Cardiovascular System 22 | 15,192
Liver and Pancreas 22 | 16,750
Respiratory system 21 | 16,393
Nervous System 20 | 16,725

Target Family

Non-IDG 11 | 12,091
Transcription Factor 10 | 1,400
Enzyme 3 | 4,145
Epigenetic 1 | 242
Kinase 1 | 634

GO Process

developmental growth 26 | 26
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nucleic acid dioxygenase ALKBH1 ALKBH1 Tbio Enzyme -2.09946 119.6 149
Receptor for retinol uptake STRA6 STRA6 Tbio Non-IDG -1.78205 67.9 157
Zinc finger MIZ domain-containing protein 1 ZMIZ1 Tbio Transcription Factor -1.57174 37.9 126
Thymidylate synthase TYMS Tclin Enzyme -2.93426 732.0 733
Carbohydrate sulfotransferase 11 CHST11 Tbio Enzyme -1.44765 27.4 112
Homeobox protein Hox-A11 HOXA11 Tbio Transcription Factor -1.96653 87.2 270
Protein ALEX GNAS Tbio Non-IDG -2.63356 1389.7 509
Serum response factor SRF Tbio Transcription Factor -2.94583 721.8 474
Transcription factor SOX-10 SOX10 Tbio Transcription Factor -2.69195 478.2 389
Abnormal spindle-like microcephaly-associated protein ASPM Tbio Non-IDG -1.52453 32.7 40