Development Level

Tbio 46 | 11,445
Tchem 7 | 1,598
Tdark 3 | 6,588

Collection

Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 11 | 979
preweaning lethality, incomple... 5 | 499
abnormal embryo size 4 | 220
abnormal bone structure 3 | 187
prenatal lethality 3 | 28
abnormal optic disc morphology 2 | 10
corneal opacity 2 | 32
decreased lean body mass 2 | 135
embryonic lethality prior to t... 2 | 278
increased grip strength 2 | 41
pallor 2 | 34
prenatal lethality prior to he... 2 | 87
abnormal behavior 1 | 298
abnormal body wall morphology 1 | 9
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal eating behavior 1 | 1
abnormal eye morphology 1 | 68
abnormal facial morphology 1 | 17
abnormal forced expiratory flo... 1 | 1
abnormal gait 1 | 69
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal limb morphology 1 | 13
abnormal maxilla morphology 1 | 17
abnormal nail morphology 1 | 8
abnormal neural tube closure 1 | 46
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal snout morphology 1 | 23
abnormal tail morphology 1 | 25
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 18
abnormal whole-body plethysmog... 1 | 4
altered righting response 1 | 1
anophthalmia 1 | 33
cataract 1 | 92
cleft palate 1 | 8
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased body temperature 1 | 2
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased tidal volume 1 | 1
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
fused cornea and lens 1 | 5
hemorrhage 1 | 23
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased circulating potassiu... 1 | 29
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
iris synechia 1 | 3
irregularly shaped pupil 1 | 7
microphthalmia 1 | 26
narrow eye opening 1 | 12
pale yolk sac 1 | 25
persistence of hyaloid vascula... 1 | 33
small testis 1 | 58

Disease

Carcinoma 42 | 11,493
ependymoma 29 | 4,679
ovarian cancer 26 | 8,520
osteosarcoma 24 | 7,950
atypical teratoid / rhabdoid tumor 21 | 5,112
psoriasis 19 | 6,694
medulloblastoma, large-cell 18 | 6,241
Situs Inversus 17 | 65
Autosomal recessive predisposition 16 | 1,442
glioblastoma 16 | 5,792
Kidney cancer 14 | 2,613
Breast cancer 13 | 3,578
invasive ductal carcinoma 13 | 2,951
lung cancer 13 | 4,740
Primary ciliary dyskinesia 12 | 76
group 3 medulloblastoma 12 | 4,104
malignant mesothelioma 12 | 3,232
nasopharyngeal carcinoma 12 | 1,058
primitive neuroectodermal tumor 12 | 3,035
Astrocytoma, Pilocytic 11 | 3,081
Right atrial isomerism 11 | 29
chronic rhinosinusitis 11 | 512
Ciliary Motility Disorders 10 | 38
Kartagener Syndrome 10 | 38
Situs ambiguus 10 | 25
adult high grade glioma 10 | 3,801
lung carcinoma 10 | 2,843
Cancer 9 | 2,499
Intellectual disability 9 | 1,016
astrocytic glioma 9 | 2,597
Ciliopathy 8 | 71
Liver cancer 8 | 604
Polydactyly 8 | 107
Visceral heterotaxy 8 | 14
Bardet-Biedl syndrome 7 | 51
Dull intelligence 7 | 645
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Obesity 7 | 678
Pick disease 7 | 1,894
Poor school performance 7 | 645
Short stature 7 | 531
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
lung adenocarcinoma 7 | 2,716
pancreatic cancer 7 | 2,398
ulcerative colitis 7 | 1,819
Ciliary Dyskinesia, Primary, 1 6 | 27
Cognitive delay 6 | 608
Global developmental delay 6 | 608
Mental and motor retardation 6 | 608
Nephronophthisis 6 | 80
Orbital separation excessive 6 | 244
Retinitis Pigmentosa 6 | 226
Ventricular Septal Defects 6 | 119
breast carcinoma 6 | 1,638
interstitial cystitis 6 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
non-small cell lung cancer 6 | 2,890
pituitary cancer 6 | 1,972
Anus, Imperforate 5 | 46
Atopic dermatitis 5 | 952
Atrial Septal Defects 5 | 85
Brachydactyly 5 | 156
Breast Neoplasms 5 | 445
Cleft Palate 5 | 271
Congenital heart disease 5 | 93
Cryptorchidism 5 | 296
Hydrocephalus 5 | 152
Hydronephrosis 5 | 89
Hypertensive disease 5 | 292
Increase in blood pressure 5 | 119
Mammary Neoplasms 5 | 425
Nystagmus 5 | 317
Patent ductus arteriosus 5 | 90
Recurrent respiratory infections 5 | 141
Situs ambiguous 5 | 8
Small head 5 | 374
adrenocortical carcinoma 5 | 1,428
astrocytoma 5 | 1,146
cystic fibrosis and chronic rhinosinusitis 5 | 214
ductal carcinoma in situ 5 | 1,745
oligodendroglioma 5 | 2,850
subependymal giant cell astrocytoma 5 | 2,287
Bardet-Biedl syndrome 1 4 | 22
Cataract 4 | 297
Congenital absence of spleen 4 | 10
Congenital hypoplasia of penis 4 | 176
Electroretinogram abnormal 4 | 95
Lens Opacities 4 | 231
Lobar Holoprosencephaly 4 | 20
Multicystic Dysplastic Kidney 4 | 52
Muscle hypotonia 4 | 571
Oligohydramnios 4 | 52
Polycystic Kidney - body part 4 | 18
Ulnar polydactyly of fingers 4 | 47
colon cancer 4 | 1,478
sonic hedgehog group medulloblastoma 4 | 467
spina bifida 4 | 1,074

Tissue

Endocrine System 56 | 18,159
Female tissues 55 | 17,400
Skin and soft tissues 55 | 17,230
Digestive Tract 54 | 17,369
Male tissues 54 | 17,142
Urinary Tract 54 | 16,678
Nervous System 53 | 16,725
Liver and Pancreas 52 | 16,750
Respiratory system 52 | 16,393
Blood and immune system 50 | 16,909
Cardiovascular System 49 | 15,192

Target Family

Non-IDG 38 | 12,091
Enzyme 6 | 4,145
Transcription Factor 6 | 1,400
Kinase 5 | 634
Ion Channel 1 | 344

GO Process

determination of left-right sy... 56 | 56
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Growth arrest-specific protein 8 GAS8 Tbio Non-IDG -1.20822 17.3 102
Rotatin RTTN Tbio Non-IDG -0.87856 9.51 13
Activin receptor type-2A ACVR2A Tchem Kinase -2.08745 108.0 315
Dynein intermediate chain 1, axonemal DNAI1 Tbio Non-IDG -1.90654 78.9 160
Meckel syndrome type 1 protein MKS1 Tbio Non-IDG -1.31837 20.5 59
Polycystin-2 PKD2 Tchem Ion Channel -2.63806 461.3 231
Polypeptide N-acetylgalactosaminyltransferase 11 GALNT11 Tbio Enzyme -0.66996 5.39 88
Cytoplasmic dynein 2 heavy chain 1 DYNC2H1 Tbio Non-IDG -1.60757 39.5 23
Cryptic protein CFC1 Tbio Non-IDG -1.89131 76.4 159
T-box transcription factor TBX1 TBX1 Tbio Transcription Factor -1.99519 95.5 207