Development Level

Tbio 42 | 10,625
Tchem 6 | 1,890
Tdark 6 | 7,003

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 8 | 633
preweaning lethality, incomple... 4 | 260
increased grip strength 3 | 83
abnormal bone structure 2 | 131
abnormal embryo size 2 | 112
corneal opacity 2 | 25
decreased lean body mass 2 | 195
increased bone mineral content 2 | 92
increased total body fat amoun... 2 | 57
abnormal behavior 1 | 226
abnormal body wall morphology 1 | 7
abnormal cervical vertebrae mo... 1 | 4
abnormal cornea morphology 1 | 24
abnormal cranium morphology 1 | 32
abnormal eye morphology 1 | 38
abnormal facial morphology 1 | 9
abnormal forced expiratory flo... 1 | 1
abnormal limb bud morphology 1 | 15
abnormal limb morphology 1 | 7
abnormal maxilla morphology 1 | 16
abnormal nail morphology 1 | 7
abnormal neural tube closure 1 | 37
abnormal optic disc morphology 1 | 10
abnormal rib morphology 1 | 28
abnormal snout morphology 1 | 18
abnormal tail morphology 1 | 17
abnormal tooth morphology 1 | 24
abnormal whole-body plethysmog... 1 | 4
altered righting response 1 | 1
anophthalmia 1 | 20
cleft palate 1 | 6
craniofacial phenotype 1 | 9
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased body temperature 1 | 2
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased circulating free fat... 1 | 39
decreased circulating insulin ... 1 | 75
decreased circulating triglyce... 1 | 83
decreased grip strength 1 | 123
decreased kidney weight 1 | 7
decreased lumbar vertebrae num... 1 | 62
decreased red blood cell distr... 1 | 11
decreased spleen weight 1 | 13
decreased tidal volume 1 | 1
embryonic growth retardation 1 | 28
enlarged heart 1 | 111
hemorrhage 1 | 12
impaired pupillary reflex 1 | 14
increased blood urea nitrogen ... 1 | 44
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating LDL chol... 1 | 15
increased circulating alkaline... 1 | 119
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased lymphocyte cell numb... 1 | 9
increased monocyte cell number 1 | 27
increased or absent threshold ... 1 | 128
increased prepulse inhibition 1 | 21
increased sacral vertebrae num... 1 | 62
irregularly shaped pupil 1 | 7
microphthalmia 1 | 15
narrow eye opening 1 | 15
prenatal lethality 1 | 16
prenatal lethality prior to he... 1 | 64
short snout 1 | 4
small testis 1 | 37

Disease

ovarian cancer 25 | 8,484
posterior fossa group B ependymoma 24 | 1,530
osteosarcoma 23 | 7,933
psoriasis 19 | 6,685
medulloblastoma, large-cell 18 | 6,234
Carcinoma 17 | 2,147
glioblastoma 16 | 5,572
atypical teratoid / rhabdoid tumor 13 | 4,369
invasive ductal carcinoma 13 | 2,950
lung cancer 12 | 4,466
malignant mesothelioma 12 | 3,162
pilocytic astrocytoma 12 | 3,086
primitive neuroectodermal tumor 12 | 3,031
Primary ciliary dyskinesia 11 | 73
Situs Inversus 11 | 48
nasopharyngeal carcinoma 11 | 1,056
Breast cancer 10 | 3,094
atypical teratoid/rhabdoid tumor 10 | 1,095
chronic rhinosinusitis 10 | 512
lung carcinoma 10 | 2,844
Ciliopathy 9 | 57
astrocytic glioma 9 | 2,241
Kartagener Syndrome 8 | 32
Polydactyly 8 | 93
group 3 medulloblastoma 8 | 2,254
Nephronophthisis 7 | 74
Pick disease 7 | 1,893
Visceral heterotaxy 7 | 12
ependymoma 7 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
lung adenocarcinoma 7 | 2,713
ulcerative colitis 7 | 2,087
Intellectual disability 6 | 573
Retinitis pigmentosa 6 | 153
adult high grade glioma 6 | 2,148
breast carcinoma 6 | 1,614
interstitial cystitis 6 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
pediatric high grade glioma 6 | 2,712
pituitary cancer 6 | 1,972
sonic hedgehog group medulloblastoma 6 | 1,482
Atopic dermatitis 5 | 944
Bardet-Biedl Syndrome 5 | 40
Cancer 5 | 2,346
Congenital heart disease 5 | 63
Obesity 5 | 616
adrenocortical carcinoma 5 | 1,427
astrocytoma 5 | 1,493
cystic fibrosis and chronic rhinosinusitis 5 | 213
ductal carcinoma in situ 5 | 1,745
group 4 medulloblastoma 5 | 1,875
medulloblastoma 5 | 1,524
non-small cell lung cancer 5 | 2,798
oligodendroglioma 5 | 2,849
pancreatic cancer 5 | 2,300
subependymal giant cell astrocytoma 5 | 2,287
Asphyxiating thoracic dystrophy 4 | 32
Craniofacial Abnormalities 4 | 147
Fundus dystrophy 4 | 77
Male infertility 4 | 170
Mammary Neoplasms 4 | 410
Senior-Loken syndrome 4 | 21
colon cancer 4 | 1,475
fibroadenoma 4 | 557
spina bifida 4 | 1,064
Alzheimer's disease 3 | 644
Barrett's esophagus 3 | 183
Bronchiectasis 3 | 29
Cleft palate 3 | 125
Congenital Heart Defects 3 | 37
Heart disease 3 | 279
Hydrocephalus 3 | 60
Joubert syndrome 3 | 61
Kidney Diseases 3 | 86
Meckel syndrome 3 | 48
Meckel-Gruber syndrome 3 | 15
Polycystic kidney disease 3 | 54
Refractive error 3 | 43
Rheumatoid Arthritis 3 | 1,160
Situs ambiguous 3 | 6
Situs ambiguus 3 | 6
active Crohn's disease 3 | 918
cystic fibrosis 3 | 1,665
dermatomyositis 3 | 933
facioscapulohumeral dystrophy 3 | 286
gastric cancer 3 | 430
gastric carcinoma 3 | 832
posterior fossa group A ependymoma 3 | 1,511
progressive supranuclear palsy 3 | 674
Down syndrome 2 | 548
Malignant neoplasm of prostate 2 | 67
Vascular disease 2 | 281
acute quadriplegic myopathy 2 | 1,157
aldosterone-producing adenoma 2 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
esophageal adenocarcinoma 2 | 737
mucosa-associated lymphoid tissue lymphoma 2 | 480
pancreatic carcinoma 2 | 567
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795

Tissue

Digestive Tract 54 | 18,473
Endocrine System 54 | 18,512
Female tissues 54 | 18,647
Male tissues 54 | 17,969
Nervous System 54 | 18,561
Respiratory system 54 | 17,484
Cardiovascular System 53 | 17,958
Liver and Pancreas 53 | 18,136
Skin and soft tissues 53 | 18,115
Urinary Tract 53 | 18,444
Blood and immune system 52 | 17,995

Target Family

Non-IDG 36 | 11,971
Enzyme 6 | 4,146
Transcription Factor 6 | 1,400
Kinase 5 | 634
Ion Channel 1 | 341

GO Process

determination of left/right sy... 54 | 54
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bardet-Biedl syndrome 7 protein BBS7 Tbio Non-IDG -1.02867 11.1 125
Protein DPCD DPCD Tbio Non-IDG -0.91027 7.70 88
Kinesin-like protein KIF3B KIF3B Tbio Non-IDG -1.33400 20.0 84
Fibroblast growth factor 10 FGF10 Tbio Non-IDG -2.51373 345.1 271
ADP-ribosylation factor-like protein 6 ARL6 Tbio Enzyme -1.59264 35.9 75
Cytoplasmic dynein 2 heavy chain 1 DYNC2H1 Tbio Non-IDG -1.59494 38.2 10
Polypeptide N-acetylgalactosaminyltransferase 11 GALNT11 Tbio Enzyme -0.65482 5.34 70
AP-1 complex subunit beta-1 AP1B1 Tbio Non-IDG -1.51499 33.3 58
Intraflagellar transport protein 140 homolog IFT140 Tbio Non-IDG -1.25967 18.3 40
T-box transcription factor TBX1 TBX1 Tbio Transcription Factor -1.94700 90.3 180