Development Level

Tbio 1 | 11,445

Disease

Abnormal brain FDG positron emission tomography 1 | 9
Abnormal skeletal development 1 | 60
Abnormal upper motor neuron morphology 1 | 11
Abnormality of adipose tissue 1 | 3
Abnormality of epiphysis morphology 1 | 39
Agnosia 1 | 3
Alexia 1 | 6
Alzheimer Disease 1 | 83
Anxiety 1 | 136
Anxiety disease 1 | 113
Apraxias 1 | 27
Arthralgia 1 | 90
Axonal loss 1 | 7
Babinski Reflex 1 | 100
Basal ganglia calcification 1 | 27
Behavioral variant of frontotemporal dementia 1 | 8
Bone Cysts 1 | 12
Bone pain 1 | 42
Caudate atrophy 1 | 3
Cerebral atrophy 1 | 178
Cerebral calcification 1 | 43
Compulsive hoarding 1 | 7
Cortical white matter abnormalities seen on MRI 1 | 18
Decreased bone mineral density Z score 1 | 31
Degenerative brain disorder 1 | 100
Dementia of frontal lobe type 1 | 6
Developmental arithmetic disorder 1 | 8
Developmental regression 1 | 95
Difficulty making arithmetical calculations 1 | 8
Dilated ventricles (finding) 1 | 121
Dysgraphia 1 | 20
Dyslexia 1 | 43
Dysphasia 1 | 23
Dyspnea 1 | 76
EEG with continuous slow activity 1 | 7
Echolalia 1 | 12
Electroencephalogram abnormal 1 | 101
Excess nuchal skin 1 | 30
Fatigable weakness of respiratory muscles 1 | 28
Fatigable weakness of swallowing muscles 1 | 28
Fatigue 1 | 182
Foot Deformities 1 | 30
Forgetful 1 | 40
Frontotemporal cerebral atrophy 1 | 8
Frontotemporal dementia 1 | 51
Generalized muscle weakness 1 | 57
Grammar-specific speech disorder 1 | 6
Hand deformities 1 | 32
Hyperorality 1 | 7
Hypoplasia of corpus callosum 1 | 90
Irritation - emotion 1 | 68
Leukoaraiosis 1 | 18
Leukoencephalopathies 1 | 29
Loss of developmental milestones 1 | 95
Loss of speech 1 | 16
Memory Loss 1 | 40
Memory impairment 1 | 40
Mental deterioration in childhood 1 | 95
Mood swings 1 | 77
Muscle Cramp 1 | 55
Myoclonus 1 | 74
Nerve Degeneration 1 | 121
Neuro-degenerative disease 1 | 43
Neurodegenerative Disorders 1 | 79
Neurodevelopmental regression 1 | 95
Neurogenic Muscular Atrophy 1 | 139
Neurogenic muscle atrophy, especially in the lower limbs 1 | 139
Osteochondrodysplasias 1 | 72
POLYCYSTIC LIPOMEMBRANOUS OSTEODYSPLASIA WITH SCLEROSING LEUKOENCEPHALOPATHY 1 | 2
Pain 1 | 103
Paralysed 1 | 42
Pathological fracture 1 | 20
Peripheral demyelination 1 | 16
Personality change 1 | 23
Poor speech 1 | 37
Primary Progressive Nonfluent Aphasia 1 | 7
Primitive reflexes (palmomental, snout, glabellar) 1 | 7
Problems speaking 1 | 37
Progressive non-fluent aphasia 1 | 7
Psychomotor regression 1 | 95
Psychomotor regression beginning in infancy 1 | 95
Psychomotor regression in infants 1 | 95
Psychomotor regression, progressive 1 | 95
Repeated speech 1 | 9
Respiratory Failure 1 | 104
Restlessness 1 | 14
Restrictive behavior 1 | 7
Restrictive behavior, interests, and activities 1 | 7
Semantic Dementia 1 | 7
Skeletal muscle atrophy 1 | 139
Social disinhibition 1 | 14
Speech Disorders 1 | 58
Spoken Word Recognition Deficit 1 | 6
Stereotyped Behavior 1 | 37
Stereotypic Movement Disorder 1 | 42
Supratentorial atrophy 1 | 94
Temporal cortical atrophy 1 | 6
Urinary Incontinence 1 | 50
Xerostomia 1 | 42
muscle degeneration 1 | 139

Tissue

Blood and immune system 1 | 16,909
Cardiovascular System 1 | 15,192
Digestive Tract 1 | 17,369
Endocrine System 1 | 18,159
Female tissues 1 | 17,400
Liver and Pancreas 1 | 16,750
Male tissues 1 | 17,142
Nervous System 1 | 16,725
Respiratory system 1 | 16,393
Skin and soft tissues 1 | 17,230
Urinary Tract 1 | 16,678

Target Family

Non-IDG 1 | 12,091

GO Process

detection of peptidoglycan 1 | 1
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Triggering receptor expressed on myeloid cells 2 TREM2 Tbio Non-IDG -2.42594 269.9 370