Development Level

Tbio 10 | 11,445
Tdark 4 | 6,588
Tchem 2 | 1,598

Collection

Ion Channel: IDG Consortium (T... 3 | 99

IMPC Phenotype

abnormal embryo size 2 | 220
decreased fasted circulating g... 2 | 65
preweaning lethality, complete... 2 | 979
abnormal eye morphology 1 | 68
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal placenta size 1 | 20
abnormal urinary bladder morph... 1 | 11
decreased circulating alkaline... 1 | 46
decreased circulating total pr... 1 | 49
decreased coping response 1 | 8
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
female infertility 1 | 60
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality 1 | 28

Disease

Carcinoma 13 | 11,493
Kidney cancer 8 | 2,613
Autosomal dominant polycystic kidney disease 6 | 31
ovarian cancer 6 | 8,520
atypical teratoid / rhabdoid tumor 5 | 5,112
Breast cancer 4 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
invasive ductal carcinoma 4 | 2,951
pituitary cancer 4 | 1,972
Autosomal recessive polycystic kidney disease 3 | 41
Kidney disease 3 | 430
Pick disease 3 | 1,894
Polycystic liver disease 3 | 16
Situs Inversus 3 | 65
adult high grade glioma 3 | 3,801
glioblastoma 3 | 5,792
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
malignant mesothelioma 3 | 3,232
medulloblastoma, large-cell 3 | 6,241
osteosarcoma 3 | 7,950
primitive neuroectodermal tumor 3 | 3,035
Anemia 2 | 365
Astrocytoma, Pilocytic 2 | 3,081
Atopic dermatitis 2 | 952
Autosomal recessive predisposition 2 | 1,442
Cancer 2 | 2,499
Cardiomyopathy 2 | 116
Cardiomyopathy, Dilated 2 | 83
Dilated cardiomyopathy 2 | 56
Kidney Failure 2 | 111
Melanoma 2 | 711
Polycystic Kidney - body part 2 | 18
Polycystic Kidney Diseases 2 | 20
Polycystic Kidney, Autosomal Dominant 2 | 7
Polycystic kidney disease 1 2 | 21
Polycystic kidney disease 2 2 | 11
Renal Insufficiency 2 | 90
Renal failure in adulthood 2 | 76
Skin cancer 2 | 469
breast carcinoma 2 | 1,638
ductal carcinoma in situ 2 | 1,745
ependymoma 2 | 4,679
group 4 medulloblastoma 2 | 1,855
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
psoriasis 2 | 6,694
Acantholysis 1 | 6
Acute cystitis 1 | 35
Afro-textured hair 1 | 13
Alport syndrome 1 | 21
Ameloblastoma 1 | 24
Areflexia of lower limbs 1 | 9
Blastomycosis 1 | 12
Bullous keratopathy 1 | 7
Cardiomyopathy, right ventricular 1 | 7
Colon diverticulum anatomic structure 1 | 15
Congenital hemolytic anemia 1 | 32
Curly hair (finding) 1 | 14
DYSTONIA 24 1 | 1
Deafness dystonia syndrome 1 | 21
Diabetic retinopathy 1 | 56
Difficulty running 1 | 7
Distal lower limb muscle weakness 1 | 6
Diverticular disease of colon 1 | 15
Familial isolated dilated cardiomyopathy 1 | 41
Febrile Convulsions 1 | 14
Foot dorsiflexor weakness 1 | 27
Foot-drop 1 | 27
Fragile skin 1 | 18
Increased connective tissue 1 | 7
Kinky hair texture 1 | 13
LEFT VENTRICULAR NONCOMPACTION 10 1 | 40
LEFT VENTRICULAR NONCOMPACTION 8 1 | 40
LEOPARD syndrome 1 | 20
Leprosy 1 | 73
Marfan Syndrome 1 | 15
Nappy hair texture 1 | 13
Neurodegenerative Diseases 1 | 38
Nikolsky sign 1 | 6
Orofaciodigital syndrome 1 | 21
Polycystic kidney disease, type 2 1 | 1
Renal tuberculosis 1 | 4
Reticulocytosis 1 | 20
Retinopathy of prematurity 1 | 22
Rimmed vacuoles on biopsy 1 | 15
Sparse eyebrow 1 | 42
Sparse scalp hair 1 | 42
Splenic infarction 1 | 6
Sudden death 1 | 16
Tachycardia, Ventricular 1 | 22
Tuberous sclerosis 1 | 19
Variation in muscle fiber size 1 | 16
Visceral leishmaniasis 1 | 14
Von Hippel-Lindau disease 1 | 19

Tissue

Blood and immune system 15 | 16,909
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Skin and soft tissues 15 | 17,230
Male tissues 14 | 17,142
Nervous System 14 | 16,725
Respiratory system 14 | 16,393
Urinary Tract 14 | 16,678
Cardiovascular System 12 | 15,192

Target Family

Ion Channel 9 | 344
Non-IDG 6 | 12,091
Enzyme 1 | 4,145

GO Process

detection of mechanical stimul... 16 | 16
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Polycystin-2 PKD2 Tchem Ion Channel -2.63806 461.3 231
Lipoxygenase homology domain-containing protein 1 LOXHD1 Tbio Enzyme -0.84027 6.66 18
Anoctamin-3 ANO3 Tbio Non-IDG -1.18072 15.2 79
Polycystin-1 PKD1 Tbio Non-IDG -2.60276 379.9 123
Piezo-type mechanosensitive ion channel component 2 PIEZO2 Tbio Ion Channel -2.31598 196.2 140
DENN domain-containing protein 5A DENND5A Tbio Non-IDG -0.56836 3.14 79
Polycystic kidney disease protein 1-like 3 PKD1L3 Tbio Ion Channel 0.00000 28
Polycystic kidney disease protein 1-like 2 PKD1L2 Tdark Ion Channel -0.46036 3.51 42
DENN domain-containing protein 5B DENND5B Tbio Non-IDG 0.00000 63
Polycystic kidney disease protein 1-like 1 PKD1L1 Tdark Ion Channel -0.57320 5.37 29