Development Level

Tbio 2 | 11,445

IMPC Phenotype

abnormal testis morphology 1 | 43
decreased eosinophil cell numb... 1 | 24
edema 1 | 59
enlarged lymph nodes 1 | 37
preweaning lethality, complete... 1 | 979

Disease

Cancer 2 | 2,499
Osteoarthritis 2 | 184
ANEURYSM, INTRACRANIAL BERRY, 1 (disorder) 1 | 3
ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA, FAMILIAL, 1 (disorder) 1 | 1
Abnormality of the iris 1 | 14
Acquired flat foot 1 | 72
Aneurysm of celiac artery 1 | 1
Angiodysplasia 1 | 5
Angioectasias of the lip 1 | 4
Angioectasias of the tongue 1 | 2
Aortic Valve Insufficiency 1 | 40
Aortic aneurysm, familial thoracic 3 1 | 13
Arachnodactyly 1 | 49
Arteriovenous Malformations, Cerebral 1 | 2
Arteriovenous fistulas of celiac and mesenteric vessels 1 | 3
Arteriovenous malformation 1 | 6
Arteriovenous malformation of liver 1 | 2
Ascending aortic dissection 1 | 13
Bilateral coxa valga 1 | 3
Blue sclera 1 | 32
Brain Abscess 1 | 2
Brain hemorrhage 1 | 14
Cardiomegaly 1 | 116
Cardiomyopathy, right ventricular 1 | 7
Cerebral Hemorrhage 1 | 42
Cleft uvula 1 | 27
Clubbing 1 | 9
Congenital abnormality of respiratory system 1 | 3
Congenital pectus carinatum 1 | 52
Conjunctival telangiectasis 1 | 14
Cutis marmorata 1 | 32
Cyanosis 1 | 17
Cystic medial necrosis of aorta 1 | 13
Decreased muscle mass 1 | 28
Descending aortic dissection 1 | 13
Dyspnea 1 | 76
Dyspnea on exertion 1 | 24
Dyspnea, Paroxysmal 1 | 13
Erythrocytosis 1 | 8
Exotropia 1 | 35
Familial primary pulmonary hypertension 1 | 11
Familial thoracic aortic aneurysm and aortic dissection 1 | 13
Feces color: tarry 1 | 2
Finger pad telangiectases 1 | 2
Flatfoot 1 | 73
Gastrointestinal angiodysplasia 1 | 3
Gastrointestinal arteriovenous malformation 1 | 2
Gastrointestinal telangiectasia 1 | 2
Hemangioma, Cavernous 1 | 20
Hematemesis 1 | 4
Hematochezia 1 | 9
Hereditary hemorrhagic telangiectasia 1 | 13
High-output congestive heart failure 1 | 1
Hypertension, Portal 1 | 22
Impaired left ventricular function 1 | 16
Increased arm span 1 | 2
Intermittent migraine headaches 1 | 68
Iron-Refractory Iron Deficiency Anemia 1 | 15
Ischemic stroke 1 | 4
Juvenile polyposis syndrome 1 | 7
Kyphoscoliosis deformity of spine 1 | 60
Left-Sided Heart Failure 1 | 16
Leiomyoma 1 | 32
Lip telangiectases 1 | 4
Loeys-Dietz Aortic Aneurysm Syndrome 1 | 13
Loeys-Dietz syndrome 1 | 23
Loeys-Dietz syndrome 4 1 | 4
Melena 1 | 2
Mesenteric artery aneurysm 1 | 1
Metabolic syndrome X 1 | 52
Migraine Disorders 1 | 76
Mitral regurgitation, mild 1 | 32
Mitral valve insufficiency 1 | 49
Nail bed telangiectases 1 | 2
Nasal mucosa telangiectasia 1 | 2
Palatal spider veins 1 | 2
Palate telangiectases 1 | 2
Polycythemia 1 | 25
Primary pulmonary hypertension 1 | 14
Pulmonary Fibrosis 1 | 106
Pulmonary arteriovenous malformation 1 | 2
RIENHOFF SYNDROME 1 | 1
Respiratory System Abnormalities 1 | 3
Right to left cardiovascular shunt (finding) 1 | 3
Spider veins of the lip 1 | 4
Spinal arteriovenous malformation 1 | 2
Spontaneous haematoma 1 | 8
Spontaneous, recurrent epistaxis 1 | 3
Subarachnoid Hemorrhage 1 | 7
Tall stature 1 | 34
Telangiectasia of the skin 1 | 39
Telangiectasia, Hereditary Hemorrhagic 1 | 3
Telangiectasia, Hereditary Hemorrhagic, of Rendu, Osler, and Weber 1 | 1
Telangiectasis 1 | 36
Tongue telangiectasia 1 | 2
Tracheal stenosis 1 | 23
Uterine fibroid 1 | 28
Venous varicosities of celiac and mesenteric vessels 1 | 1
Visceral angiomatosis 1 | 13
arrhythmogenic right ventricular dysplasia 1 1 | 1

Tissue

Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

Non-IDG 2 | 12,091

GO Process

detection of hypoxia 2 | 2
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Transforming growth factor beta-3 TGFB3 Tbio Non-IDG -3.02749 1062.5 308