Development Level

Tbio 8 | 11,445

IMPC Phenotype

decreased blood urea nitrogen ... 1 | 51

Disease

osteosarcoma 6 | 7,950
Cancer 4 | 2,499
Carcinoma 4 | 11,493
group 3 medulloblastoma 4 | 4,104
lung cancer 4 | 4,740
glioblastoma 3 | 5,792
medulloblastoma, large-cell 3 | 6,241
ovarian cancer 3 | 8,520
primitive neuroectodermal tumor 3 | 3,035
psoriasis 3 | 6,694
tuberculosis 3 | 2,010
Autosomal recessive predisposition 2 | 1,442
Cockayne syndrome 2 | 60
Multiple myeloma 2 | 1,332
Pick disease 2 | 1,894
Waldenstrons macroglobulinemia 2 | 765
Xeroderma pigmentosum group G 2 | 16
astrocytic glioma 2 | 2,597
atypical teratoid / rhabdoid tumor 2 | 5,112
breast carcinoma 2 | 1,638
dermatomyositis 2 | 966
malignant mesothelioma 2 | 3,232
oligodendroglioma 2 | 2,850
Adenocarcinoma 1 | 122
Adenocarcinoma of lung 1 | 142
Adenocarcinoma of lung (disorder) 1 | 60
Adenoma 1 | 167
Adenomatous Polyposis Coli 1 | 16
Aphasia 1 | 26
Apraxia 1 | 26
Arthropathy 1 | 43
Autistic Disorder 1 | 364
Bloom syndrome 1 | 29
Brain Diseases 1 | 24
Carcinoma, Renal Cell 1 | 124
Cerebrovascular disease 1 | 238
Colorectal Neoplasms 1 | 243
Colorectal adenoma 1 | 15
Dementia 1 | 175
Dermatologic disorders 1 | 93
Dyslipidemias 1 | 27
Encephalitis 1 | 64
Epididymitis 1 | 8
Fatty Liver 1 | 70
Fibrous dysplasia 1 | 15
Frontotemporal dementia 1 | 51
Gastrointestinal system disease 1 | 54
Glucose Intolerance 1 | 19
Hearing Loss, Noise-Induced 1 | 5
Heart Diseases 1 | 43
Heart disease 1 | 306
Hemangioma 1 | 69
Huntington Disease 1 | 13
Hyperinsulinism 1 | 133
Hyperlipidemia 1 | 43
IgG Deficiency 1 | 22
Immunoglobulin A deficiency (disorder) 1 | 19
Immunologic Deficiency Syndromes 1 | 113
Impaired Ig class-switch recombination (CSR) 1 | 3
Impaired glucose tolerance 1 | 28
Increased IgM levels 1 | 16
Increased susceptibility to bacterial infections 1 | 42
Insulin Resistance 1 | 72
Intracranial hypotension 1 | 10
Isolated cases 1 | 72
Leiomyoma 1 | 32
Lung Neoplasms 1 | 232
Lung disease 1 | 142
Lymphadenopathy 1 | 62
Lymphatic system disease 1 | 15
Lymphoma 1 | 81
Lymphoproliferative syndrome 1 | 58
Lynch syndrome 1 | 35
Malignant neoplasm of skin 1 | 15
Meningioma 1 | 41
Metabolic syndrome X 1 | 52
Motor Skills Disorders 1 | 8
Movement disease 1 | 11
Multiple system atrophy 1 | 29
Nerve Degeneration 1 | 121
Neurilemmoma 1 | 23
Noise-induced hearing loss 1 | 5
Osteomyelitis 1 | 42
Pancreatitis 1 | 123
Papilledema 1 | 11
Parkinson's disease 1 | 392
Prenatal Exposure Delayed Effects 1 | 11
Prone to bacterial infection 1 | 42
Recurrent bacterial infection 1 | 42
Renal Cell Carcinoma 1 | 214
Renal Cell Carcinoma, Nonpapillary 1 | 7
Skin Diseases 1 | 71
Skin Neoplasms 1 | 69
Takayasu's arteritis 1 | 53
Urologic Neoplasms 1 | 8
Vasculitis 1 | 80
Xeroderma pigmentosum group D 1 | 33
Xeroderma pigmentosum group F 1 | 22
atypical teratoid/rhabdoid tumor 1 | 357
sarcoidosis 1 | 370

Tissue

Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Enzyme 7 | 4,145
Transcription Factor 1 | 1,400

GO Process

depyrimidination 8 | 8
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endonuclease III-like protein 1 NTHL1 Tbio Enzyme -1.85066 66.8 155
G/T mismatch-specific thymine DNA glycosylase TDG Tbio Enzyme -2.46252 297.6 225
Single-strand selective monofunctional uracil DNA glycosylase SMUG1 Tbio Enzyme -4.31831 20587.4 199
Uracil-DNA glycosylase UNG Tbio Enzyme -2.82957 680.9 352
N-glycosylase/DNA lyase OGG1 Tbio Enzyme -3.26147 1834.9 293
Methyl-CpG-binding domain protein 4 MBD4 Tbio Transcription Factor -1.99625 98.6 183
Endonuclease 8-like 2 NEIL2 Tbio Enzyme -1.74921 49.0 107
Endonuclease 8-like 1 NEIL1 Tbio Enzyme -2.01238 106.1 202