Development Level

Tbio 9 | 11,445
Tchem 3 | 1,598
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal embryo development 1 | 7
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal pericardium morpholog... 1 | 26
decreased cardiac muscle contr... 1 | 11
decreased erythrocyte cell num... 1 | 62
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
increased cardiac muscle contr... 1 | 8
increased heart rate variabili... 1 | 7
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74

Disease

atypical teratoid / rhabdoid tumor 12 | 5,112
glioblastoma 10 | 5,792
Carcinoma 9 | 11,493
medulloblastoma, large-cell 9 | 6,241
ependymoma 8 | 4,679
lung cancer 8 | 4,740
osteosarcoma 8 | 7,950
Astrocytoma, Pilocytic 6 | 3,081
Cancer 6 | 2,499
group 4 medulloblastoma 6 | 1,855
oligodendroglioma 6 | 2,850
ovarian cancer 6 | 8,520
pancreatic cancer 6 | 2,398
primitive neuroectodermal tumor 6 | 3,035
psoriasis 6 | 6,694
Schizophrenia 5 | 1,160
Breast cancer 4 | 3,578
Dull intelligence 4 | 645
Intellectual disability 4 | 1,016
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Pick disease 4 | 1,894
Poor school performance 4 | 645
astrocytic glioma 4 | 2,597
group 3 medulloblastoma 4 | 4,104
invasive ductal carcinoma 4 | 2,951
lung adenocarcinoma 4 | 2,716
malignant mesothelioma 4 | 3,232
non-small cell lung cancer 4 | 2,890
pediatric high grade glioma 4 | 1,064
subependymal giant cell astrocytoma 4 | 2,287
Cognitive delay 3 | 608
Global developmental delay 3 | 608
Mental and motor retardation 3 | 608
Neoplasm Metastasis 3 | 168
Parkinson's disease 3 | 392
Seizures 3 | 596
adult high grade glioma 3 | 3,801
astrocytoma 3 | 1,146
colon cancer 3 | 1,478
cutaneous lupus erythematosus 3 | 1,057
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
lung carcinoma 3 | 2,843
medulloblastoma 3 | 720
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,109
Acquired metabolic disease 2 | 336
Agenesis of corpus callosum 2 | 83
Angiokeratoma 2 | 9
Autistic Disorder 2 | 364
Autosomal recessive predisposition 2 | 1,442
Bipolar Disorder 2 | 666
Breast Neoplasms 2 | 445
Carcinoma, Hepatocellular 2 | 228
Chloracne 2 | 32
Chronic Lymphocytic Leukemia 2 | 262
Dermatologic disorders 2 | 93
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Dilated ventricles (finding) 2 | 121
Epilepsy 2 | 792
Glioma 2 | 74
Kidney cancer 2 | 2,613
Liver cancer 2 | 604
Liver carcinoma 2 | 240
Lung Neoplasms 2 | 232
Lymphangioma 2 | 9
Lymphedema 2 | 42
Meningioma 2 | 41
Mesothelioma, Malignant 2 | 105
Neoplasm Invasiveness 2 | 161
Orbital separation excessive 2 | 244
Short stature 2 | 531
Skin cancer 2 | 469
Strabismus 2 | 270
Syndactyly of fingers 2 | 48
acute myeloid leukemia 2 | 783
adrenocortical carcinoma 2 | 1,428
aldosterone-producing adenoma 2 | 665
breast carcinoma 2 | 1,638
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
gastric carcinoma 2 | 807
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
posterior fossa group B ependymoma 2 | 416
sarcoidosis 2 | 370
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
urothelial carcinoma 2 | 318
Basal cell carcinoma of skin 1 | 2
Curry-Jones syndrome 1 | 1
Fissured tongue 1 | 25
MATURITY-ONSET DIABETES OF THE YOUNG, TYPE 6 (disorder) 1 | 1
MODY, Type 6 1 | 1
Maturity onset diabetes mellitus in young 1 | 11
Maturity-Onset Diabetes of the Young, Type 6 1 | 1
Tuberous sclerosis 1 | 19

Tissue

Endocrine System 14 | 18,159
Nervous System 14 | 16,725
Skin and soft tissues 14 | 17,230
Digestive Tract 13 | 17,369
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Urinary Tract 13 | 16,678
Blood and immune system 12 | 16,909
Male tissues 12 | 17,142
Cardiovascular System 11 | 15,192
Respiratory system 11 | 16,393

Target Family

Transcription Factor 6 | 1,400
Non-IDG 3 | 12,091
GPCR 2 | 408
Enzyme 1 | 4,145
Epigenetic 1 | 242
Kinase 1 | 634
Nuclear Receptor 1 | 48

GO Process

dentate gyrus development 15 | 15
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Smoothened homolog SMO Tclin GPCR -1.17466 14.5 415
Protein BTG2 BTG2 Tbio Non-IDG -2.10376 142.7 209
Neurogenic differentiation factor 6 NEUROD6 Tbio Transcription Factor -1.51923 32.8 133
D(1A) dopamine receptor DRD1 Tclin GPCR -2.55049 294.2 485
Prospero homeobox protein 1 PROX1 Tbio Transcription Factor -2.31691 210.1 472
Homeobox protein EMX2 EMX2 Tbio Transcription Factor -2.04282 110.8 265
LIM homeobox transcription factor 1-alpha LMX1A Tbio Transcription Factor -1.82498 66.0 175
Nuclear receptor subfamily 2 group E member 1 NR2E1 Tbio Nuclear Receptor -1.67371 50.0 223
Neurogenic differentiation factor 1 NEUROD1 Tbio Transcription Factor -2.56661 344.4 371
Lymphoid enhancer-binding factor 1 LEF1 Tchem Transcription Factor -2.60971 375.2 591