Development Level

Tbio 128 | 10,625
Tchem 16 | 1,890
Tclin 10 | 602
Tdark 6 | 7,003

IMPC Term

decreased bone mineral content 6 | 157
embryonic lethality prior to t... 5 | 187
preweaning lethality, complete... 5 | 633
decreased CD4-positive, CD25-p... 4 | 24
embryonic lethality prior to o... 4 | 148
increased circulating HDL chol... 4 | 63
abnormal embryo size 3 | 112
decreased B cell number 3 | 30
decreased neutrophil cell numb... 3 | 37
decreased total body fat amoun... 3 | 186
abnormal behavior 2 | 226
abnormal bone structure 2 | 131
abnormal neural tube closure 2 | 37
abnormal retina morphology 2 | 100
decreased CD8-positive, alpha-... 2 | 26
decreased Ly6C low monocyte nu... 2 | 23
decreased body length 2 | 108
decreased bone mineral density 2 | 126
decreased fasted circulating g... 2 | 49
decreased grip strength 2 | 123
decreased heart weight 2 | 44
decreased lean body mass 2 | 195
decreased mean corpuscular hem... 2 | 34
decreased mean corpuscular vol... 2 | 50
decreased monocyte cell number 2 | 28
enlarged lymph nodes 2 | 27
impaired glucose tolerance 2 | 52
increased bone mineral content 2 | 92
increased lean body mass 2 | 107
increased mean corpuscular vol... 2 | 91
abnormal coat/ hair morphology 1 | 18
abnormal coat/hair pigmentatio... 1 | 54
abnormal coping response 1 | 12
abnormal forebrain development 1 | 18
abnormal gait 1 | 51
abnormal hair growth 1 | 8
abnormal hindbrain development 1 | 24
abnormal iris morphology 1 | 12
abnormal midbrain development 1 | 22
abnormal placenta size 1 | 10
abnormal posture 1 | 5
abnormal retinal pigmentation 1 | 61
abnormal tail movements 1 | 12
abnormal tooth morphology 1 | 24
decreased CD4-positive, alpha ... 1 | 19
decreased CD5-positive Ly6C-po... 1 | 4
decreased KLRG1+ CD8 alpha bet... 1 | 8
decreased NK T cell number 1 | 28
decreased T cell number 1 | 31
decreased alpha-beta T cell nu... 1 | 12
decreased circulating HDL chol... 1 | 77
decreased circulating alkaline... 1 | 41
decreased circulating choleste... 1 | 85
decreased circulating fructosa... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating magnesiu... 1 | 11
decreased effector memory CD4-... 1 | 6
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased gamma-delta T cell n... 1 | 18
decreased lumbar vertebrae num... 1 | 62
decreased mature B cell number 1 | 25
decreased prepulse inhibition 1 | 52
decreased rib number 1 | 59
enlarged heart 1 | 111
enlarged urinary bladder 1 | 4
female infertility 1 | 34
hypoactivity 1 | 89
improved glucose tolerance 1 | 56
increased B cell number 1 | 23
increased NK cell number 1 | 19
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating phosphat... 1 | 24
increased circulating total pr... 1 | 20
increased grip strength 1 | 83
increased heart weight 1 | 37
increased lymphocyte cell numb... 1 | 9
increased mature B cell number 1 | 12
increased mean corpuscular hem... 1 | 93
increased mean platelet volume 1 | 19
increased total body fat amoun... 1 | 57
oligodactyly 1 | 14
pale yolk sac 1 | 12
pallor 1 | 13
polydactyly 1 | 22
preweaning lethality, incomple... 1 | 260
small superior vagus ganglion 1 | 20
tremors 1 | 34

Disease

ovarian cancer 82 | 8,484
psoriasis 74 | 6,685
lung cancer 69 | 4,466
osteosarcoma 69 | 7,933
glioblastoma 64 | 5,572
medulloblastoma, large-cell 62 | 6,234
lung carcinoma 52 | 2,844
cutaneous lupus erythematosus 51 | 1,056
Cancer 48 | 2,346
ulcerative colitis 47 | 2,087
intraductal papillary-mucinous neoplasm (IPMN) 46 | 3,289
pilocytic astrocytoma 46 | 3,086
juvenile dermatomyositis 44 | 1,189
Multiple Sclerosis 40 | 498
pancreatic cancer 40 | 2,300
Influenza 38 | 142
malignant mesothelioma 38 | 3,162
primary Sjogren syndrome 37 | 789
cystic fibrosis 36 | 1,665
atypical teratoid / rhabdoid tumor 35 | 4,369
intraductal papillary-mucinous carcinoma (IPMC) 34 | 2,988
subependymal giant cell astrocytoma 34 | 2,287
active Crohn's disease 33 | 918
pediatric high grade glioma 33 | 2,712
interstitial cystitis 32 | 2,299
invasive ductal carcinoma 32 | 2,950
intraductal papillary-mucinous adenoma (IPMA) 31 | 2,956
dermatomyositis 30 | 933
non-small cell lung cancer 30 | 2,798
tuberculosis 30 | 1,557
Breast cancer 28 | 3,094
group 4 medulloblastoma 28 | 1,875
lung adenocarcinoma 25 | 2,713
Multiple myeloma 24 | 1,327
adult high grade glioma 23 | 2,148
systemic lupus erythematosus 23 | 156
Hepatitis C 22 | 90
Rheumatoid Arthritis 22 | 1,160
pituitary cancer 21 | 1,972
diabetes mellitus 20 | 1,663
posterior fossa group A ependymoma 20 | 1,511
astrocytoma 19 | 1,493
ependymoma 19 | 2,514
primary pancreatic ductal adenocarcinoma 18 | 1,271
Hepatitis B 17 | 103
Carcinoma 16 | 2,147
breast carcinoma 16 | 1,614
primitive neuroectodermal tumor 16 | 3,031
Asthma 15 | 349
Atopic dermatitis 15 | 944
nasopharyngeal carcinoma 15 | 1,056
Hepatitis 14 | 61
Hypersensitivity reaction type II disease 14 | 235
Inflammatory bowel disease 14 | 142
esophageal adenocarcinoma 14 | 737
Arthritis 13 | 248
acute quadriplegic myopathy 13 | 1,157
ductal carcinoma in situ 13 | 1,745
group 3 medulloblastoma 13 | 2,254
oligodendroglioma 13 | 2,849
colon cancer 12 | 1,475
hepatocellular carcinoma 12 | 532
medulloblastoma 12 | 1,524
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,795
posterior fossa group B ependymoma 12 | 1,530
Dermatitis 11 | 107
Down syndrome 11 | 548
Duchenne muscular dystrophy 11 | 602
Encephalitis 11 | 54
Lung disease 11 | 132
Pick disease 11 | 1,893
adrenocortical carcinoma 11 | 1,427
sarcoidosis 11 | 358
Waldenstrons macroglobulinemia 10 | 765
astrocytic glioma 10 | 2,241
pancreatic carcinoma 10 | 567
Anemia 9 | 252
Human immunodeficiency virus infectious disease 9 | 92
Kidney disease 9 | 396
Mammary Neoplasms 9 | 410
Melanoma 9 | 261
Vascular disease 9 | 281
acute myeloid leukemia 9 | 780
gastric carcinoma 9 | 832
inflammatory breast cancer 9 | 404
Acquired immunodeficiency syndrome 8 | 164
Endometriosis 8 | 535
Prostatic Neoplasms 8 | 471
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 499
gastric cancer 8 | 430
mucosa-associated lymphoid tissue lymphoma 8 | 480
tuberculosis and treatment for 6 months 8 | 686
Allergic hypersensitivity disease 7 | 123
IGA Glomerulonephritis 7 | 454
Myocardial Ischemia 7 | 169
Stomach Neoplasms 7 | 282
aldosterone-producing adenoma 7 | 664
glioblastoma multiforme 7 | 347
non primary Sjogren syndrome sicca 7 | 840
urothelial carcinoma 7 | 318

Tissue

Nervous System 157 | 18,561
Digestive Tract 156 | 18,473
Female tissues 156 | 18,647
Skin and soft tissues 154 | 18,115
Urinary Tract 154 | 18,444
Blood and immune system 152 | 17,995
Endocrine System 152 | 18,512
Liver and Pancreas 149 | 18,136
Cardiovascular System 148 | 17,958
Respiratory system 147 | 17,484
Male tissues 141 | 17,969

Target Family

Non-IDG 104 | 11,971
Enzyme 39 | 4,146
Transcription Factor 8 | 1,400
Kinase 4 | 634
GPCR 2 | 406
Transporter 2 | 473
Ion Channel 1 | 341

GO Process

defense response to virus 160 | 160
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nuclear cap-binding protein subunit 3 NCBP3 Tbio Non-IDG -1.68208 49.3 22
Interferon lambda receptor 1 IFNLR1 Tchem Non-IDG -1.48464 33.1 128
Interferon regulatory factor 9 IRF9 Tbio Transcription Factor -1.79340 61.7 168
Interferon lambda-1 IFNL1 Tbio Non-IDG -1.90881 86.4 137
Interleukin enhancer-binding factor 3 ILF3 Tbio Non-IDG -2.09543 135.8 239
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 AIMP1 Tbio Enzyme -2.04569 136.6 321
Interleukin-10 receptor subunit beta IL10RB Tbio Non-IDG -1.82576 55.5 177
Cytosolic carboxypeptidase-like protein 5 AGBL5 Tbio Enzyme -0.95984 10.3 115
Toll-like receptor 7 TLR7 Tclin Non-IDG -2.92878 974.2 670
Interferon lambda-2 IFNL2 Tbio Non-IDG -1.52337 33.7 143