Development Level

Tbio 51 | 10,625
Tchem 15 | 1,890
Tclin 5 | 602
Tdark 4 | 7,003

IMPC Phenotype

increased body weight 2 | 42
abnormal coping response 1 | 12
abnormal heart morphology 1 | 51
abnormal vibrissa morphology 1 | 17
decreased circulating bilirubi... 1 | 14
decreased circulating glycerol... 1 | 19
decreased grip strength 1 | 123
decreased mean corpuscular vol... 1 | 50
decreased monocyte cell number 1 | 28
decreased neutrophil cell numb... 1 | 37
enlarged heart 1 | 111
increased blood urea nitrogen ... 1 | 44
increased circulating HDL chol... 1 | 63
increased circulating LDL chol... 1 | 15
increased circulating alkaline... 1 | 119
increased circulating choleste... 1 | 53
increased effector memory CD8-... 1 | 14
increased eosinophil cell numb... 1 | 9
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased leukocyte cell numbe... 1 | 37
increased lymphocyte cell numb... 1 | 9
increased mean corpuscular hem... 1 | 93
increased neutrophil cell numb... 1 | 15
premature death 1 | 5
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260
vertebral fusion 1 | 23

Disease

psoriasis 41 | 6,685
Cancer 32 | 2,346
osteosarcoma 30 | 7,933
ovarian cancer 28 | 8,491
lung carcinoma 24 | 2,844
glioblastoma 22 | 5,572
lung cancer 20 | 4,473
pilocytic astrocytoma 19 | 3,086
ulcerative colitis 19 | 2,087
interstitial cystitis 18 | 2,299
medulloblastoma, large-cell 18 | 6,234
invasive ductal carcinoma 17 | 2,950
diabetes mellitus 16 | 1,663
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,289
Breast cancer 15 | 3,098
atypical teratoid / rhabdoid tumor 15 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,956
non-small cell lung cancer 15 | 2,798
tuberculosis 15 | 1,563
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,988
Arthritis 13 | 248
Asthma 13 | 349
cystic fibrosis 13 | 1,670
Rheumatoid Arthritis 12 | 1,170
lung adenocarcinoma 12 | 2,714
pancreatic cancer 12 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,795
pituitary cancer 12 | 1,972
subependymal giant cell astrocytoma 12 | 2,287
cutaneous lupus erythematosus 11 | 1,056
pediatric high grade glioma 11 | 2,712
Crohn's disease 10 | 304
Hypersensitivity reaction type II disease 10 | 235
Hypertension 10 | 293
Pneumonia 10 | 133
malignant mesothelioma 10 | 3,163
Atopic dermatitis 9 | 944
Inflammatory bowel disease 9 | 142
Kidney disease 9 | 397
Multiple Sclerosis 9 | 498
Obesity 9 | 616
Waldenstrons macroglobulinemia 9 | 764
colon cancer 9 | 1,475
Coronary artery disease 8 | 240
Diarrhea 8 | 155
Malaria 8 | 140
dermatomyositis 8 | 966
juvenile dermatomyositis 8 | 1,189
periodontitis 8 | 269
posterior fossa group A ependymoma 8 | 1,511
Ankylosing spondylitis 7 | 138
Atherosclerosis 7 | 275
Cerebrovascular disease 7 | 231
Liver disease 7 | 219
Lung disease 7 | 136
Osteoporosis 7 | 259
Peritonitis 7 | 37
Reperfusion Injury 7 | 84
Uveitis 7 | 103
adrenocortical carcinoma 7 | 1,427
adult high grade glioma 7 | 2,148
breast carcinoma 7 | 1,614
group 3 medulloblastoma 7 | 2,254
Allergic hypersensitivity disease 6 | 123
Alzheimer's disease 6 | 644
Amyloidosis 6 | 68
Bipolar Disorder 6 | 266
Candidiasis 6 | 48
Dermatitis 6 | 141
Heart disease 6 | 279
Inflammation 6 | 109
Influenza 6 | 142
Keratitis 6 | 42
Major Depressive Disorder 6 | 106
Mastitis 6 | 48
Neurodegenerative disease 6 | 383
Pancreatitis 6 | 97
Peripheral Neuropathy 6 | 303
Progressive relapsing multiple sclerosis 6 | 18
Schizophrenia 6 | 503
astrocytoma 6 | 1,493
ductal carcinoma in situ 6 | 1,745
mucosa-associated lymphoid tissue lymphoma 6 | 480
oligodendroglioma 6 | 2,849
Crohn Disease 5 | 97
Endometriosis 5 | 535
Hepatitis B 5 | 103
Leishmaniasis 5 | 49
Metabolic syndrome X 5 | 155
Multiple myeloma 5 | 1,327
Myocardial Ischemia 5 | 169
Neuropathy 5 | 210
Pick disease 5 | 1,893
Polycystic Ovary Syndrome 5 | 334
Prostatic Neoplasms 5 | 471
Toxic encephalopathy 5 | 131
active Crohn's disease 5 | 918
acute quadriplegic myopathy 5 | 1,157
medulloblastoma 5 | 1,524
primary Sjogren syndrome 5 | 788

Tissue

Digestive Tract 72 | 18,472
Female tissues 72 | 18,646
Nervous System 72 | 18,560
Urinary Tract 72 | 18,443
Cardiovascular System 71 | 17,957
Endocrine System 71 | 18,511
Blood and immune system 70 | 17,994
Male tissues 70 | 17,968
Skin and soft tissues 70 | 18,114
Liver and Pancreas 69 | 18,135
Respiratory system 68 | 17,483

Target Family

Non-IDG 50 | 11,969
Enzyme 18 | 4,146
Kinase 4 | 634
GPCR 1 | 408
Ion Channel 1 | 341
Transcription Factor 1 | 1,400

GO Process

defense response to Gram-posit... 75 | 75
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Receptor-interacting serine/threonine-protein kinase 2 RIPK2 Tchem Kinase -2.00230 103.9 435
Toll-like receptor 2 TLR2 Tchem Non-IDG -3.47133 3173.5 946
Phospholipase A2 PLA2G1B Tchem Enzyme -3.16422 1303.1 195
Ephrin type-A receptor 2 EPHA2 Tclin Kinase -2.87482 785.1 704
Tumor necrosis factor ligand superfamily member 8 TNFSF8 Tbio Non-IDG -1.76681 62.9 201
Interleukin-27 receptor subunit alpha IL27RA Tbio Non-IDG -1.84130 74.8 267
Lysozyme-like protein 4 LYZL4 Tbio Enzyme -0.84062 6.98 65
Lysozyme-like protein 1 LYZL1 Tdark Enzyme -0.55544 3.40 81
Secreted protein C10orf99 C10orf99 Tbio Non-IDG -1.80584 63.7 3
Peptidoglycan recognition protein 3 PGLYRP3 Tbio Non-IDG -1.59825 37.9 39