Development Level

Tbio 89 | 11,445
Tchem 13 | 1,598
Tdark 7 | 6,588

Collection

Kinase: IDG Consortium (Target... 5 | 125
RFA-RM-18-021 5 | 328
GPCR: IDG Consortium (Complete... 1 | 25
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 6 | 979
preweaning lethality, incomple... 5 | 499
abnormal embryo size 3 | 220
abnormal seminal vesicle morph... 3 | 114
decreased total body fat amoun... 3 | 207
abnormal bone structure 2 | 187
decreased circulating sodium l... 2 | 22
decreased erythrocyte cell num... 2 | 62
enlarged lymph nodes 2 | 37
female infertility 2 | 60
increased circulating alkaline... 2 | 122
increased lean body mass 2 | 172
increased mean corpuscular vol... 2 | 92
small testis 2 | 58
abnormal QT variability 1 | 10
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal coat appearance 1 | 31
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal digit morphology 1 | 10
abnormal forebrain morphology 1 | 10
abnormal hindbrain morphology 1 | 10
abnormal iris morphology 1 | 13
abnormal iris pigmentation 1 | 4
abnormal liver morphology 1 | 17
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal pelvic girdle bone mo... 1 | 12
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal skin coloration 1 | 25
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
abnormal tail morphology 1 | 25
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 18
absent urinary bladder 1 | 1
cataract 1 | 92
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating bilirubi... 1 | 19
decreased circulating glucose ... 1 | 126
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased thermal nociceptive ... 1 | 2
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
eye hemorrhage 1 | 1
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased caudal vertebrae num... 1 | 7
increased circulating LDL chol... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating triglyce... 1 | 42
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 81 | 11,493
osteosarcoma 63 | 7,950
ovarian cancer 52 | 8,520
psoriasis 51 | 6,694
glioblastoma 47 | 5,792
atypical teratoid / rhabdoid tumor 46 | 5,112
medulloblastoma, large-cell 46 | 6,241
ependymoma 39 | 4,679
Breast cancer 34 | 3,578
adult high grade glioma 34 | 3,801
malignant mesothelioma 32 | 3,232
intraductal papillary-mucinous adenoma (IPMA) 31 | 2,955
Kidney cancer 30 | 2,613
lung cancer 30 | 4,740
group 3 medulloblastoma 28 | 4,104
non-small cell lung cancer 28 | 2,890
primitive neuroectodermal tumor 27 | 3,035
Astrocytoma, Pilocytic 26 | 3,081
intraductal papillary-mucinous carcinoma (IPMC) 26 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 26 | 3,291
lung carcinoma 26 | 2,843
invasive ductal carcinoma 25 | 2,951
pancreatic cancer 25 | 2,398
breast carcinoma 23 | 1,638
interstitial cystitis 23 | 2,312
subependymal giant cell astrocytoma 22 | 2,287
lung adenocarcinoma 21 | 2,716
oligodendroglioma 21 | 2,850
Cancer 20 | 2,499
group 4 medulloblastoma 20 | 1,855
spina bifida 20 | 1,074
Pick disease 19 | 1,894
tuberculosis 19 | 2,010
ductal carcinoma in situ 18 | 1,745
astrocytic glioma 17 | 2,597
cystic fibrosis 17 | 1,696
ulcerative colitis 17 | 1,819
adrenocortical carcinoma 16 | 1,428
colon cancer 15 | 1,478
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
gastric carcinoma 14 | 807
pituitary cancer 14 | 1,972
primary pancreatic ductal adenocarcinoma 14 | 1,109
esophageal adenocarcinoma 13 | 737
nasopharyngeal carcinoma 13 | 1,058
Autosomal recessive predisposition 11 | 1,442
acute myeloid leukemia 10 | 783
Alzheimer's disease 9 | 658
Atopic dermatitis 9 | 952
Bipolar Disorder 9 | 666
Down syndrome 9 | 499
Intellectual disability 9 | 1,016
acute quadriplegic myopathy 9 | 1,158
juvenile dermatomyositis 9 | 1,187
pediatric high grade glioma 9 | 1,064
fibroadenoma 8 | 559
Asthma 7 | 385
Liver cancer 7 | 604
Rheumatoid arthritis 7 | 1,191
cutaneous lupus erythematosus 7 | 1,057
diabetes mellitus 7 | 1,728
Short stature 6 | 531
active Crohn's disease 6 | 922
astrocytoma 6 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
dermatomyositis 6 | 966
mucosa-associated lymphoid tissue lymphoma 6 | 484
progressive supranuclear palsy 6 | 676
Aarskog syndrome 5 | 12
Depressive disorder 5 | 409
Dermatitis 5 | 157
Duchenne muscular dystrophy 5 | 601
Esophageal Squamous Cell Carcinoma 5 | 77
HIV Infections 5 | 102
Hypereosinophilic syndrome 5 | 71
Hypersensitivity 5 | 63
Neurodegenerative disease 5 | 414
Neuropathy 5 | 261
Polycystic ovary syndrome 5 | 360
Schizophrenia 5 | 1,160
Squamous cell carcinoma of esophagus 5 | 77
Waldenstrons macroglobulinemia 5 | 765
interstitial lung disease 5 | 298
medulloblastoma 5 | 720
non primary Sjogren syndrome sicca 5 | 891
pancreatic carcinoma 5 | 562
sonic hedgehog group medulloblastoma 5 | 467
Atherosclerosis 4 | 291
Crohn's disease 4 | 321
Dull intelligence 4 | 645
Heart disease 4 | 306
Major Depressive Disorder 4 | 301
Mental Depression 4 | 333
Multiple Sclerosis 4 | 540
Multiple myeloma 4 | 1,332
Type 2 diabetes mellitus 4 | 272
Unipolar Depression 4 | 250
active ulcerative colitis 4 | 764
gastric cancer 4 | 459
hepatocellular carcinoma 4 | 547

Tissue

Female tissues 108 | 17,400
Skin and soft tissues 108 | 17,230
Blood and immune system 106 | 16,909
Digestive Tract 106 | 17,369
Endocrine System 106 | 18,159
Liver and Pancreas 106 | 16,750
Male tissues 106 | 17,142
Urinary Tract 106 | 16,678
Nervous System 104 | 16,725
Respiratory system 103 | 16,393
Cardiovascular System 101 | 15,192

Target Family

Non-IDG 76 | 12,091
Enzyme 15 | 4,145
Kinase 11 | 634
Epigenetic 4 | 242
Transcription Factor 2 | 1,400
GPCR 1 | 408

GO Process

cytoskeleton organization 109 | 109
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Desmin DES Tbio Non-IDG -1.56068 36.6 991
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 ARAP3 Tbio Non-IDG -0.96067 13.8 85
TRAF2 and NCK-interacting protein kinase TNIK Tchem Kinase -1.33394 28.5 441
PH-interacting protein PHIP Tbio Epigenetic -2.17655 144.9 65
Tetraspanin-32 TSPAN32 Tbio Non-IDG -0.97140 8.31 153
Palladin PALLD Tbio Non-IDG -2.73002 528.8 164
Formimidoyltransferase-cyclodeaminase FTCD Tbio Enzyme -2.23276 170.0 418
C-C motif chemokine 13 CCL13 Tbio Non-IDG -2.02640 99.2 264
Keratin, type II cytoskeletal 2 oral KRT76 Tdark Non-IDG -0.28255 1.97 156
Zinc finger protein 135 ZNF135 Tbio Transcription Factor -2.08875 114.1 68