Development Level

Tbio 10 | 11,445

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal embryo size 1 | 220
decreased bone mineral content 1 | 151
decreased coping response 1 | 8
decreased fasted circulating g... 1 | 65
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
increased hemoglobin content 1 | 45
prenatal lethality 1 | 28

Disease

Carcinoma 10 | 11,493
atypical teratoid / rhabdoid tumor 10 | 5,112
Kidney cancer 8 | 2,613
ependymoma 8 | 4,679
glioblastoma 7 | 5,792
adult high grade glioma 6 | 3,801
primitive neuroectodermal tumor 6 | 3,035
psoriasis 6 | 6,694
Astrocytoma, Pilocytic 5 | 3,081
group 3 medulloblastoma 5 | 4,104
oligodendroglioma 5 | 2,850
osteosarcoma 5 | 7,950
pituitary cancer 5 | 1,972
Autosomal recessive predisposition 4 | 1,442
Intellectual disability 4 | 1,016
Liver cancer 4 | 604
invasive ductal carcinoma 4 | 2,951
lung cancer 4 | 4,740
medulloblastoma, large-cell 4 | 6,241
ovarian cancer 4 | 8,520
Breast cancer 3 | 3,578
Dull intelligence 3 | 645
Low intelligence 3 | 645
Melanoma 3 | 711
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Pick disease 3 | 1,894
Poor school performance 3 | 645
Prostatic Neoplasms 3 | 495
Schizophrenia 3 | 1,160
astrocytic glioma 3 | 2,597
diabetes mellitus 3 | 1,728
ductal carcinoma in situ 3 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung adenocarcinoma 3 | 2,716
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
tuberculosis 3 | 2,010
Amyotrophic lateral sclerosis 2 | 451
Autistic Disorder 2 | 364
Cancer 2 | 2,499
Carcinoma, Renal Cell 2 | 124
Cardiomyopathy 2 | 116
Cataract 2 | 297
Cleft Lip 2 | 141
Common variable immunodeficiency 2 | 101
Crohn's disease 2 | 321
Duchenne muscular dystrophy 2 | 601
Lens Opacities 2 | 231
Muscle hypotonia 2 | 571
Nonorganic psychosis 2 | 84
Polycystic ovary syndrome 2 | 360
Psychotic Disorders 2 | 151
Renal Cell Carcinoma 2 | 214
Skin cancer 2 | 469
acute quadriplegic myopathy 2 | 1,158
aldosterone-producing adenoma 2 | 665
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
gastric cancer 2 | 459
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
malignant mesothelioma 2 | 3,232
nephrosclerosis 2 | 333
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
sarcoidosis 2 | 370
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
urothelial carcinoma 2 | 318
11 pairs of ribs 1 | 7
Abnormality of the metacarpal bones 1 | 17
Afro-textured hair 1 | 13
Aplasia/Hypoplasia of the abdominal wall musculature 1 | 17
Brachyonychia 1 | 6
Broad distal phalanges 1 | 2
Broad face 1 | 7
Cardiomyopathy, right ventricular 1 | 7
Clear cell ependymoma 1 | 4
Compression of spinal cord 1 | 10
Congenital pectus carinatum 1 | 52
Curly hair (finding) 1 | 14
Equinovalgus deformity 1 | 4
Graves' disease 1 | 24
Hitchhiker thumb 1 | 3
Isolated somatotropin deficiency 1 | 30
Kinky hair texture 1 | 13
LEOPARD syndrome 1 | 20
Larsen syndrome 1 | 10
Nappy hair texture 1 | 13
Poor head control 1 | 14
Short metatarsal 1 | 21
Spatulate thumbs 1 | 3
Tachycardia, Ventricular 1 | 22
Talipes Equinovalgus 1 | 4
Tarsal Coalition 1 | 12
Thin hypoplastic alae nasi 1 | 51
Tibial bowing 1 | 19
Tracheal stenosis 1 | 23

Tissue

Blood and immune system 10 | 16,909
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678
Cardiovascular System 9 | 15,192
Respiratory system 9 | 16,393

Target Family

Non-IDG 9 | 12,091
Enzyme 1 | 4,145

GO Process

cytoskeletal anchoring at plas... 10 | 10
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Talin-2 TLN2 Tbio Non-IDG -1.36153 20.0 101
Ankyrin-3 ANK3 Tbio Non-IDG -2.25280 172.9 170
Dystroglycan DAG1 Tbio Enzyme -2.77503 560.0 254
Spectrin beta chain, non-erythrocytic 4 SPTBN4 Tbio Non-IDG -1.35996 22.3 58
Filamin-B FLNB Tbio Non-IDG -2.43075 263.4 168
Ezrin EZR Tbio Non-IDG -2.99865 981.3 1088
Talin-1 TLN1 Tbio Non-IDG -1.94109 90.0 426
SH3 and multiple ankyrin repeat domains protein 1 SHANK1 Tbio Non-IDG -1.58468 39.2 170
Junction plakoglobin JUP Tbio Non-IDG -2.01808 101.8 719
Band 4.1-like protein 3 EPB41L3 Tbio Non-IDG -2.05631 121.6 203