Development Level

Tbio 9 | 11,445
Tchem 2 | 1,598
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal limb bud morphology 1 | 17
abnormal liver size 1 | 5
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal stomach morphology 1 | 10
decreased circulating alkaline... 1 | 46
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
pale liver 1 | 6
pale yolk sac 1 | 25
pallor 1 | 34
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 10 | 11,493
ovarian cancer 9 | 8,520
Cancer 6 | 2,499
Liver Cirrhosis, Experimental 4 | 769
glioblastoma 4 | 5,792
lung adenocarcinoma 4 | 2,716
medulloblastoma, large-cell 4 | 6,241
osteosarcoma 4 | 7,950
psoriasis 4 | 6,694
Breast cancer 3 | 3,578
Kidney disease 3 | 430
Pick disease 3 | 1,894
Rheumatoid arthritis 3 | 1,191
astrocytoma 3 | 1,146
atypical teratoid / rhabdoid tumor 3 | 5,112
colon cancer 3 | 1,478
lung cancer 3 | 4,740
Arthritis, Rheumatoid 2 | 174
Autosomal dominant polycystic kidney disease 2 | 31
Autosomal recessive polycystic kidney disease 2 | 41
Chronic Lymphocytic Leukemia 2 | 262
Coarse facial features 2 | 108
Frontal bossing 2 | 157
Kidney Failure 2 | 111
Kidney cancer 2 | 2,613
Multiple myeloma 2 | 1,332
Orbital separation excessive 2 | 244
Polycystic Kidney - body part 2 | 18
Polycystic Kidney Diseases 2 | 20
Polycystic Kidney, Autosomal Dominant 2 | 7
Polycystic liver disease 2 | 16
Prostatic Neoplasms 2 | 495
Renal Insufficiency 2 | 90
Renal failure in adulthood 2 | 76
Thickened facial skin with coarse facial features 2 | 108
adult high grade glioma 2 | 3,801
breast carcinoma 2 | 1,638
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
malignant mesothelioma 2 | 3,232
medulloblastoma 2 | 720
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
spina bifida 2 | 1,074
subependymal giant cell astrocytoma 2 | 2,287
Accessory rib 1 | 10
Amelogenesis imperfecta type 1E 1 | 3
Anhidrosis 1 | 23
Basal Cell Nevus Syndrome 1 | 5
Basal cell nevi 1 | 23
Breast adenoma 1 | 4
Calcification of falx cerebri 1 | 6
Cardiac fibroma 1 | 3
Cardiac rhabdomyoma 1 | 5
Cerebral calcification 1 | 43
Colon diverticulum anatomic structure 1 | 15
Congenital anomaly of neck 1 | 19
Congenital fusion of ribs 1 | 4
Congenital hypothyroidism 1 | 26
Deformity of neck 1 | 19
Diverticular disease of colon 1 | 15
Ectodermal dysplasia, hypohidrotic, with immune deficiency 1 | 2
Fused vertebrae 1 | 25
Gallbladder Neoplasms 1 | 10
Goiter 1 | 38
Gorlin syndrome 1 | 4
Hamartomatous stomach polyps 1 | 3
Hepatitis 1 | 67
Hyperthyroidism 1 | 53
Hypohidrotic ectodermal dysplasia with immunodeficiency 1 | 2
Irregular ossification of hand bones 1 | 3
Keratocystic Odontogenic Tumor 1 | 3
Keratosis 1 | 37
Kyphoscoliosis deformity of spine 1 | 60
Malformation of the neck 1 | 19
Malignant neoplasm of prostate 1 | 11
Malignant tumor of prostate 1 | 26
Melioidosis 1 | 17
Milium Cyst 1 | 16
Mycosis fungoides 1 | 29
Neurodegenerative Diseases 1 | 38
Orbital cyst 1 | 8
Ovarian Fibromata 1 | 3
Palmar pit 1 | 4
Parietal bossing 1 | 5
Plantar pits 1 | 4
Relapsing remitting multiple sclerosis 1 | 14
Relative macrocephaly 1 | 12
Saddle nose 1 | 6
Sella Turcica, Bridged 1 | 3
Short 4th metacarpal 1 | 7
Short ribs 1 | 30
Short thumb terminal phalanx 1 | 5
Skin tag 1 | 14
Sloping shoulders 1 | 21
Spinal fusion 1 | 25
Sprengel deformity 1 | 16
Sternal anomalies 1 | 19
Vertebral body fusion 1 | 25
Vertebral wedging 1 | 4
gallbladder neoplasm 1 | 10

Tissue

Blood and immune system 13 | 16,909
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Male tissues 13 | 17,142
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678
Cardiovascular System 12 | 15,192
Liver and Pancreas 12 | 16,750
Nervous System 12 | 16,725

Target Family

Non-IDG 9 | 12,091
Transcription Factor 2 | 1,400
Ion Channel 1 | 344
Nuclear Receptor 1 | 48

GO Process

cytoplasmic sequestering of tr... 13 | 13
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
MyoD family inhibitor MDFI Tbio Non-IDG -1.71031 47.9 104
Polycystin-2 PKD2 Tchem Ion Channel -2.63806 461.3 231
Max-interacting protein 1 MXI1 Tbio Transcription Factor -2.03408 107.7 179
Sorcin SRI Tbio Non-IDG -2.69915 481.5 119
Polycystin-1 PKD1 Tbio Non-IDG -2.60276 379.9 123
NF-kappa-B inhibitor-like protein 1 NFKBIL1 Tbio Non-IDG -1.41875 29.3 137
NF-kappa-B inhibitor epsilon NFKBIE Tbio Non-IDG -1.39025 20.6 313
Kelch-like ECH-associated protein 1 KEAP1 Tclin Non-IDG -2.99364 962.4 463
Tonsoku-like protein TONSL Tbio Non-IDG -0.77322 6.12 130
Suppressor of fused homolog SUFU Tbio Non-IDG -2.33544 208.6 168