Development Level

Tbio 23 | 11,178
Tchem 8 | 1,885
Tdark 2 | 6,569
Tclin 1 | 612

IMPC Phenotype

preweaning lethality, complete... 7 | 979
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
abnormal lens morphology 2 | 81
abnormal retina morphology 2 | 71
cataract 2 | 92
embryonic lethality prior to o... 2 | 239
abnormal QT variability 1 | 10
abnormal craniofacial morpholo... 1 | 33
abnormal embryo turning 1 | 31
abnormal forebrain morphology 1 | 10
abnormal hindbrain morphology 1 | 10
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
absent startle reflex 1 | 24
cardiovascular system phenotyp... 1 | 36
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating aspartat... 1 | 34
decreased grip strength 1 | 116
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased exploration in new e... 1 | 8
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
persistence of hyaloid vascula... 1 | 33
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
small spleen 1 | 19
thrombocytopenia 1 | 56

Disease

ovarian cancer 23 | 8,297
Carcinoma 22 | 11,192
medulloblastoma, large-cell 18 | 6,086
osteosarcoma 17 | 7,766
atypical teratoid / rhabdoid tumor 15 | 4,971
glioblastoma 15 | 5,635
psoriasis 15 | 6,514
Kidney cancer 13 | 2,548
lung cancer 12 | 4,607
adult high grade glioma 11 | 3,701
ependymoma 11 | 4,559
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,204
group 3 medulloblastoma 10 | 4,002
invasive ductal carcinoma 10 | 2,867
oligodendroglioma 10 | 2,768
Breast cancer 9 | 3,469
Cancer 9 | 2,388
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,902
non-small cell lung cancer 8 | 2,799
primitive neuroectodermal tumor 8 | 2,957
Astrocytoma, Pilocytic 7 | 3,006
astrocytic glioma 7 | 2,530
breast carcinoma 7 | 1,589
malignant mesothelioma 7 | 3,135
colon cancer 6 | 1,428
pancreatic cancer 6 | 2,322
Multiple myeloma 5 | 1,296
Schizophrenia 5 | 1,136
ductal carcinoma in situ 5 | 1,686
interstitial cystitis 5 | 2,237
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,872
lung adenocarcinoma 5 | 2,627
non primary Sjogren syndrome sicca 5 | 861
subependymal giant cell astrocytoma 5 | 2,230
Autosomal recessive predisposition 4 | 1,407
Neurodegenerative disease 4 | 402
Pick disease 4 | 1,856
Waldenstrons macroglobulinemia 4 | 742
group 4 medulloblastoma 4 | 1,806
medulloblastoma 4 | 702
primary pancreatic ductal adenocarcinoma 4 | 1,071
ulcerative colitis 4 | 1,765
Atopic dermatitis 3 | 915
Lung Neoplasms 3 | 217
acute quadriplegic myopathy 3 | 1,133
adrenocortical carcinoma 3 | 1,385
chronic rhinosinusitis 3 | 505
cystic fibrosis 3 | 1,629
esophageal adenocarcinoma 3 | 696
juvenile dermatomyositis 3 | 1,147
lung carcinoma 3 | 2,755
posterior fossa group A ependymoma 3 | 456
progressive supranuclear palsy 3 | 656
Amyotrophic lateral sclerosis 2 | 437
Bipolar Disorder 2 | 646
Breast Neoplasms 2 | 423
Cerebellar Ataxia 2 | 302
Charcot-Marie-Tooth disease type 4C 2 | 2
DiGeorge syndrome 2 | 46
Dull intelligence 2 | 634
Dysarthria 2 | 190
Endometriosis 2 | 521
Glioma 2 | 73
Heart disease 2 | 288
Highly variable clinical phenotype 2 | 147
Highly variable phenotype and severity 2 | 147
Highly variable phenotype, even within families 2 | 147
Hypertension 2 | 372
Impotence 2 | 44
Infertility 2 | 176
Intellectual disability 2 | 998
Liver cancer 2 | 589
Low intelligence 2 | 634
Mammary Neoplasms 2 | 403
Mental Retardation 2 | 634
Mental deficiency 2 | 634
Myocardial Infarction 2 | 142
Neurodegenerative Diseases 2 | 37
Neurodegenerative Disorders 2 | 78
Pancreatic Neoplasm 2 | 82
Pancreatic Neoplasms 2 | 82
Paraplegia 2 | 72
Phenotypic variability 2 | 147
Poor school performance 2 | 634
Premature Menopause 2 | 29
Prostate cancer 2 | 164
Psychotic Disorders 2 | 150
Shigellosis 2 | 21
Toxic encephalopathy 2 | 139
Vascular disease 2 | 294
Velocardiofacial syndrome 2 | 46
acute myeloid leukemia 2 | 760
astrocytoma 2 | 1,113
cutaneous lupus erythematosus 2 | 1,016
diabetes mellitus 2 | 1,683
hereditary spastic paraplegia 2 | 313
mucosa-associated lymphoid tissue lymphoma 2 | 473
pituitary cancer 2 | 1,915
primary Sjogren syndrome 2 | 710
tuberculosis 2 | 1,963

Tissue

Blood and immune system 34 | 16,909
Digestive Tract 34 | 17,369
Endocrine System 34 | 18,159
Female tissues 34 | 17,400
Liver and Pancreas 34 | 16,750
Male tissues 34 | 17,142
Nervous System 34 | 16,725
Skin and soft tissues 34 | 17,230
Urinary Tract 34 | 16,678
Respiratory system 33 | 16,393
Cardiovascular System 32 | 15,192

Target Family

Non-IDG 25 | 12,091
Enzyme 4 | 4,145
Kinase 4 | 634
Epigenetic 1 | 242

GO Process

cytokinesis 34 | 34
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras-related protein Rab-35 RAB35 Tbio Enzyme -1.61645 42.9 224
Kelch-like protein 13 KLHL13 Tdark Non-IDG -0.01524 0.81 85
Protein diaphanous homolog 2 DIAPH2 Tbio Non-IDG -1.70372 49.0 172
Zinc finger FYVE domain-containing protein 26 ZFYVE26 Tbio Non-IDG -1.09554 12.6 39
Microtubule-associated protein 9 MAP9 Tbio Non-IDG -0.79253 5.85 61
Septin-5 SEPT5 Tbio Non-IDG -1.71017 49.4 178
Rho guanine nucleotide exchange factor 11 ARHGEF11 Tbio Non-IDG -1.61227 42.0 183
Protein ELYS AHCTF1 Tbio Non-IDG -1.39546 23.9 74
Ropporin-1B ROPN1B Tbio Non-IDG 1.00 0.10 59
Cat eye syndrome critical region protein 2 CECR2 Tchem Epigenetic -2.17030 147.0 44