Development Level

Tbio 32 | 10,625
Tchem 13 | 1,890
Tdark 2 | 7,003
Tclin 1 | 602

Collection

Eligible Kinase Proteins 2 | 134

IMPC Term

preweaning lethality, complete... 7 | 633
decreased grip strength 2 | 123
preweaning lethality, incomple... 2 | 260
abnormal behavior 1 | 226
abnormal embryo size 1 | 112
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal lens morphology 1 | 73
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal placenta size 1 | 10
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
cardiovascular system phenotyp... 1 | 35
craniofacial phenotype 1 | 9
decreased body weight 1 | 174
decreased circulating aspartat... 1 | 27
decreased circulating creatini... 1 | 31
decreased mature B cell number 1 | 25
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged lymph nodes 1 | 27
improved glucose tolerance 1 | 56
increased circulating alkaline... 1 | 119
increased exploration in new e... 1 | 56
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular vol... 1 | 91
increased or absent threshold ... 1 | 128
short tibia 1 | 82
small spleen 1 | 11
thrombocytopenia 1 | 46
tremors 1 | 34

Disease

ovarian cancer 34 | 8,484
medulloblastoma, large-cell 30 | 6,234
osteosarcoma 25 | 7,933
glioblastoma 24 | 5,572
psoriasis 22 | 6,685
lung cancer 19 | 4,466
atypical teratoid / rhabdoid tumor 18 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,289
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,988
malignant mesothelioma 14 | 3,162
pediatric high grade glioma 14 | 2,712
Cancer 13 | 2,346
Carcinoma 13 | 2,147
invasive ductal carcinoma 13 | 2,950
primitive neuroectodermal tumor 13 | 3,031
breast carcinoma 12 | 1,614
ependymoma 12 | 2,514
non-small cell lung cancer 12 | 2,798
oligodendroglioma 12 | 2,849
pancreatic cancer 12 | 2,300
Breast cancer 10 | 3,094
lung adenocarcinoma 10 | 2,713
subependymal giant cell astrocytoma 10 | 2,287
colon cancer 9 | 1,475
group 3 medulloblastoma 9 | 2,254
group 4 medulloblastoma 9 | 1,875
astrocytic glioma 8 | 2,241
ductal carcinoma in situ 8 | 1,745
pilocytic astrocytoma 8 | 3,086
Multiple myeloma 7 | 1,327
adrenocortical carcinoma 7 | 1,427
posterior fossa group A ependymoma 7 | 1,511
Atopic dermatitis 6 | 944
adult high grade glioma 6 | 2,148
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
sonic hedgehog group medulloblastoma 6 | 1,482
Endometriosis 5 | 535
IGA Glomerulonephritis 5 | 454
Pick disease 5 | 1,893
atypical teratoid/rhabdoid tumor 5 | 1,095
interstitial cystitis 5 | 2,299
medulloblastoma 5 | 1,524
non primary Sjogren syndrome sicca 5 | 840
primary pancreatic ductal adenocarcinoma 5 | 1,271
tuberculosis 5 | 1,557
ulcerative colitis 5 | 2,087
Lung Neoplasms 4 | 171
Neurodegenerative disease 4 | 383
Waldenstrons macroglobulinemia 4 | 765
acute quadriplegic myopathy 4 | 1,157
astrocytoma 4 | 1,493
chronic rhinosinusitis 4 | 512
cystic fibrosis 4 | 1,665
diabetes mellitus 4 | 1,663
esophageal adenocarcinoma 4 | 737
inflammatory breast cancer 4 | 404
juvenile dermatomyositis 4 | 1,189
lung carcinoma 4 | 2,844
nasopharyngeal carcinoma 4 | 1,056
Amyotrophic Lateral Sclerosis 3 | 431
Gaucher disease type 1 3 | 171
Mammary Neoplasms 3 | 410
Renal Cell Carcinoma 3 | 199
Rheumatoid Arthritis 3 | 1,160
active Crohn's disease 3 | 918
acute myeloid leukemia 3 | 780
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
pituitary cancer 3 | 1,972
posterior fossa group B ependymoma 3 | 1,530
progressive supranuclear palsy 3 | 674
tuberculosis and treatment for 6 months 3 | 686
Cerebellar Ataxia 2 | 72
Colonic Neoplasms 2 | 126
DiGeorge syndrome 2 | 46
Diabetes Mellitus, Non-Insulin-Dependent 2 | 157
Down syndrome 2 | 548
Glioma 2 | 65
Impotence 2 | 45
Infertility 2 | 163
Liver carcinoma 2 | 217
Malignant neoplasm of breast 2 | 63
Microcephaly 2 | 149
Myocardial Infarction 2 | 126
Neurodegenerative Disorders 2 | 37
Pancreatic Neoplasm 2 | 79
Stomach Neoplasms 2 | 282
Toxic encephalopathy 2 | 131
Vascular disease 2 | 281
Velocardiofacial syndrome 2 | 45
cone-rod dystrophy 2 | 56
cutaneous lupus erythematosus 2 | 1,056
dermatomyositis 2 | 933
fibroadenoma 2 | 557
hereditary spastic paraplegia 2 | 313
mucosa-associated lymphoid tissue lymphoma 2 | 480
non-small cell lung carcinoma 2 | 413
ovarian neoplasm 2 | 97
periodontitis 2 | 269
primary Sjogren syndrome 2 | 789
Roberts syndrome 1 | 16

Tissue

Blood and immune system 48 | 17,995
Cardiovascular System 48 | 17,958
Digestive Tract 48 | 18,473
Endocrine System 48 | 18,512
Female tissues 48 | 18,647
Liver and Pancreas 48 | 18,136
Male tissues 48 | 17,969
Nervous System 48 | 18,561
Respiratory system 48 | 17,484
Skin and soft tissues 48 | 18,115
Urinary Tract 48 | 18,444

Target Family

Non-IDG 30 | 11,971
Enzyme 9 | 4,146
Kinase 8 | 634
Epigenetic 1 | 242

GO Process

cytokinesis 48 | 48
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ropporin-1B ROPN1B Tbio Non-IDG 1.00 0.10 52
Rho guanine nucleotide exchange factor 11 ARHGEF11 Tbio Non-IDG -1.54485 39.7 163
Ras-related protein Rab-11A RAB11A Tbio Enzyme -2.60207 398.9 288
Rab11 family-interacting protein 4 RAB11FIP4 Tbio Non-IDG -0.60511 4.75 34
Protein ELYS AHCTF1 Tbio Non-IDG -1.30356 22.8 57
Ras-related protein Ral-B RALB Tbio Enzyme -1.69182 49.7 204
Ras-related protein Ral-A RALA Tbio Enzyme -2.17133 159.2 185
Rab11 family-interacting protein 3 RAB11FIP3 Tbio Non-IDG -0.81358 5.58 60
Rho-associated protein kinase 2 ROCK2 Tclin Kinase -2.39656 248.3 472
Phosphatidylinositol 3-kinase catalytic subunit type 3 PIK3C3 Tchem Kinase -2.26683 181.8 641