Development Level

Tbio 18 | 11,445
Tclin 3 | 613
Tchem 2 | 1,598

IMPC Phenotype

preweaning lethality, incomple... 4 | 499
abnormal behavioral response t... 1 | 66
abnormal retina morphology 1 | 71
decreased circulating bilirubi... 1 | 19
decreased hematocrit 1 | 46
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
edema 1 | 59
increased circulating alkaline... 1 | 122
increased mean corpuscular hem... 1 | 36

Disease

osteosarcoma 18 | 7,950
Carcinoma 16 | 11,493
ovarian cancer 16 | 8,520
psoriasis 14 | 6,694
Cancer 11 | 2,499
glioblastoma 10 | 5,792
ependymoma 9 | 4,679
invasive ductal carcinoma 9 | 2,951
medulloblastoma, large-cell 9 | 6,241
Kidney cancer 8 | 2,613
atypical teratoid / rhabdoid tumor 8 | 5,112
Astrocytoma, Pilocytic 7 | 3,081
adult high grade glioma 7 | 3,801
breast carcinoma 7 | 1,638
group 3 medulloblastoma 7 | 4,104
Liver Cirrhosis, Experimental 6 | 769
diabetes mellitus 6 | 1,728
lung cancer 6 | 4,740
lung carcinoma 6 | 2,843
oligodendroglioma 6 | 2,850
Breast cancer 5 | 3,578
Pick disease 5 | 1,894
astrocytic glioma 5 | 2,597
astrocytoma 5 | 1,146
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
subependymal giant cell astrocytoma 5 | 2,287
ulcerative colitis 5 | 1,819
Gaucher disease type 1 4 | 180
Hypertension 4 | 396
ductal carcinoma in situ 4 | 1,745
juvenile dermatomyositis 4 | 1,187
malignant mesothelioma 4 | 3,232
non-small cell lung cancer 4 | 2,890
tuberculosis 4 | 2,010
Breast Neoplasms 3 | 445
Duchenne muscular dystrophy 3 | 601
Glaucoma 3 | 239
Mammary Neoplasms 3 | 425
Melanoma 3 | 711
Neoplasm Invasiveness 3 | 161
Osteoporosis 3 | 363
Rheumatoid arthritis 3 | 1,191
Schizophrenia 3 | 1,160
Waldenstrons macroglobulinemia 3 | 765
active Crohn's disease 3 | 922
active ulcerative colitis 3 | 764
acute myeloid leukemia 3 | 783
acute quadriplegic myopathy 3 | 1,158
colon cancer 3 | 1,478
cutaneous lupus erythematosus 3 | 1,057
cystic fibrosis 3 | 1,696
esophageal adenocarcinoma 3 | 737
fibroadenoma 3 | 559
gastric carcinoma 3 | 807
group 4 medulloblastoma 3 | 1,855
pancreatic cancer 3 | 2,398
pituitary cancer 3 | 1,972
primary Sjogren syndrome 3 | 735
primitive neuroectodermal tumor 3 | 3,035
Agammaglobulinemia 2 | 34
Alzheimer's disease 2 | 658
Amyotrophic lateral sclerosis 2 | 451
Anemia 2 | 365
Arthritis, Rheumatoid 2 | 174
Autosomal recessive predisposition 2 | 1,442
Bipolar Disorder 2 | 666
Brain disease 2 | 96
Cerebral Ischemia 2 | 37
Chagas disease 2 | 39
Colorectal Neoplasms 2 | 243
Dementia 2 | 175
Down syndrome 2 | 499
Heart disease 2 | 306
Hyperglycemia 2 | 137
Hypertensive disease 2 | 292
Impotence 2 | 42
Malaria 2 | 160
Multiple Sclerosis 2 | 540
Myocardial Infarction 2 | 151
Myocardial Ischemia 2 | 169
Obesity 2 | 678
Ocular hypertension 2 | 42
Parkinson's disease 2 | 392
Polycystic ovary syndrome 2 | 360
Toxic encephalopathy 2 | 141
adrenocortical carcinoma 2 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
head and neck cancer and chronic obstructive pulmonary disease 2 | 239
hereditary spastic paraplegia 2 | 318
lung adenocarcinoma 2 | 2,716
medulloblastoma 2 | 720
nasopharyngeal carcinoma 2 | 1,058
nephrosclerosis 2 | 333
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primary pancreatic ductal adenocarcinoma 2 | 1,109
sarcoidosis 2 | 370
spina bifida 2 | 1,074

Tissue

Blood and immune system 23 | 16,909
Digestive Tract 23 | 17,369
Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Liver and Pancreas 23 | 16,750
Male tissues 23 | 17,142
Nervous System 23 | 16,725
Respiratory system 23 | 16,393
Skin and soft tissues 23 | 17,230
Urinary Tract 23 | 16,678
Cardiovascular System 22 | 15,192

Target Family

Non-IDG 15 | 12,091
Enzyme 4 | 4,145
Kinase 4 | 634

GO Process

cortical actin cytoskeleton or... 23 | 23
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Rho-associated protein kinase 1 ROCK1 Tclin Kinase -2.64622 378.2 461
Ras-related protein Rab-13 RAB13 Tbio Enzyme -1.40524 27.4 73
Caveolae-associated protein 3 CAVIN3 Tbio Enzyme -1.39796 28.7 150
Rho-related GTP-binding protein RhoQ RHOQ Tbio Enzyme -1.48059 28.3 111
Striatin-interacting protein 1 STRIP1 Tbio Non-IDG -0.72783 5.30 102
Lethal(2) giant larvae protein homolog 1 LLGL1 Tbio Non-IDG -3.09201 1212.4 143
Nck-associated protein 1-like NCKAP1L Tbio Non-IDG -1.07556 11.2 127
Cyclin-dependent-like kinase 5 CDK5 Tchem Kinase -3.06393 1238.4 694
EH domain-containing protein 2 EHD2 Tbio Non-IDG -1.49972 32.2 144
Talin-1 TLN1 Tbio Non-IDG -1.94109 90.0 426