Development Level

Tbio 8 | 11,445

IMPC Phenotype

edema 1 | 59
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 6 | 11,493
psoriasis 4 | 6,694
Autosomal recessive predisposition 3 | 1,442
Glaucoma 3 | 239
ependymoma 3 | 4,679
malignant mesothelioma 3 | 3,232
medulloblastoma, large-cell 3 | 6,241
Abnormality of vision 2 | 40
Aniridia 2 | 25
Anterior Segment Dysgenesis 5 2 | 4
Astrocytoma, Pilocytic 2 | 3,081
Blindness 2 | 88
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Cataract 2 | 297
Cloudy cornea 2 | 33
Cognitive delay 2 | 608
Coloboma 2 | 51
Congenital aphakia 2 | 6
Cornea plana 2 | 12
Corneal disease 2 | 31
Corneal stromal opacities 2 | 33
Cryptorchidism 2 | 296
Dull intelligence 2 | 645
Global developmental delay 2 | 608
Intellectual disability 2 | 1,016
Irido-corneo-trabecular dysgenesis (disorder) 2 | 10
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Microphthalmia 2 | 76
Muscle hypotonia 2 | 571
Neoplasm Invasiveness 2 | 161
Nystagmus 2 | 317
Peters anomaly 2 | 16
Poor school performance 2 | 645
Sclerocornea 2 | 29
Short stature 2 | 531
Small head 2 | 374
Strabismus 2 | 270
Tooth Abnormalities 2 | 69
astrocytic glioma 2 | 2,597
atypical teratoid/rhabdoid tumor 2 | 357
chronic rhinosinusitis 2 | 512
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
oligodendroglioma 2 | 2,850
ovarian cancer 2 | 8,520
Abnormality of the iris 1 | 14
Abnormality of the nares 1 | 2
Anterior segment mesenchymal dysgenesis 1 | 7
Aortic aneurysm, familial thoracic 3 1 | 13
Ascending aortic dissection 1 | 13
Axenfeld-Rieger Syndrome, Type 1 1 | 3
Bladder exstrophy 1 | 32
Bowed and upward slanting eyebrows 1 | 41
Bullous keratopathy 1 | 7
Bushy eyebrows 1 | 49
CATARACT, AUTOSOMAL DOMINANT 1 | 4
Coloboma of eyelid 1 | 15
Coloboma of lens 1 | 4
Coloboma of macula 1 | 4
Coloboma of optic disc 1 | 9
Congenital coloboma of iris 1 | 4
Corneal ectasia 1 | 11
Cutis marmorata 1 | 32
Cystic medial necrosis of aorta 1 | 13
Descending aortic dissection 1 | 13
Dyspnea on exertion 1 | 24
Dyspnea, Paroxysmal 1 | 13
Ectropion 1 | 38
Everted lower lip vermilion 1 | 54
Exposure keratitis 1 | 5
Familial thoracic aortic aneurysm and aortic dissection 1 | 13
Full lower lip 1 | 64
Generalized hyperpigmentation 1 | 22
Hereditary macular coloboma 1 | 5
Hypertrichosis 1 | 46
Impaired left ventricular function 1 | 16
Keratopathy 1 | 12
Left-Sided Heart Failure 1 | 16
Lens subluxation 1 | 12
Loeys-Dietz Aortic Aneurysm Syndrome 1 | 13
Long nose 1 | 15
Optic disc abnormalities 1 | 12
Persistent hyperplastic primary vitreous 1 | 20
Posterior amorphous corneal dystrophy 1 | 9
Prominent lower lip 1 | 64
Protruding lower lip 1 | 54
Reduced visual acuity 1 | 63
Renal coloboma syndrome 1 | 4
Short distal phalanges 1 | 50
Short lower third of face 1 | 9
Slow-growing hair 1 | 19
Small chin 1 | 9
Thick vermilion border 1 | 25
Thick, flared eyebrows 1 | 41
Thin hypoplastic alae nasi 1 | 51
Waardenburg's syndrome 1 | 17

Tissue

Endocrine System 8 | 18,159
Blood and immune system 7 | 16,909
Digestive Tract 7 | 17,369
Female tissues 7 | 17,400
Nervous System 7 | 16,725
Skin and soft tissues 7 | 17,230
Male tissues 6 | 17,142
Respiratory system 6 | 16,393
Urinary Tract 6 | 16,678
Cardiovascular System 5 | 15,192
Liver and Pancreas 5 | 16,750

Target Family

Non-IDG 5 | 12,091
Transcription Factor 3 | 1,400

GO Process

cornea development in camera-t... 8 | 8
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein Wnt-6 WNT6 Tbio Non-IDG -1.65830 46.6 186
Forkhead box protein E3 FOXE3 Tbio Transcription Factor -1.53701 31.5 150
Paired box protein Pax-6 PAX6 Tbio Transcription Factor -3.16650 1458.6 570
Protein Wnt-2b WNT2B Tbio Non-IDG -1.76988 58.0 172
Transcription factor SOX-11 SOX11 Tbio Transcription Factor -2.01545 106.1 219
Keratocan KERA Tbio Non-IDG -2.22798 161.3 105
Protein Wnt-9a WNT9A Tbio Non-IDG -1.41160 26.6 141
Protein Wnt-9b WNT9B Tbio Non-IDG -1.44759 27.3 98