Development Level

Tbio 5 | 11,445

IMPC Phenotype

abnormal behavior 1 | 298
hyperactivity 1 | 148
increased body length 1 | 32
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 5 | 11,493
osteosarcoma 4 | 7,950
Anemia 3 | 365
Astrocytoma, Pilocytic 3 | 3,081
Breast cancer 3 | 3,578
atypical teratoid / rhabdoid tumor 3 | 5,112
cystic fibrosis 3 | 1,696
glioblastoma 3 | 5,792
group 3 medulloblastoma 3 | 4,104
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
lung cancer 3 | 4,740
ovarian cancer 3 | 8,520
pituitary cancer 3 | 1,972
tuberculosis 3 | 2,010
Disease Models, Animal 2 | 155
Dull intelligence 2 | 645
Ecchymosis 2 | 66
Hemoglobin low 2 | 124
Hepatomegaly 2 | 285
Increased tendency to bruise 2 | 66
Intellectual disability 2 | 1,016
Liver Neoplasms, Experimental 2 | 59
Low intelligence 2 | 645
MEDNIK syndrome 2 | 8
Menkes disease 2 | 19
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Osteoporosis 2 | 363
Pick disease 2 | 1,894
Poor school performance 2 | 645
Prostatic Neoplasms 2 | 495
Splenomegaly 2 | 190
Tremor 2 | 113
Wilson disease 2 | 16
adult high grade glioma 2 | 3,801
ependymoma 2 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
medulloblastoma, large-cell 2 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primitive neuroectodermal tumor 2 | 3,035
psoriasis 2 | 6,694
subependymal giant cell astrocytoma 2 | 2,287
urothelial carcinoma 2 | 318
Acquired flat foot 1 | 72
Acute hepatitis 1 | 2
Afro-textured hair 1 | 13
Anemia, Hemolytic 1 | 55
Aneurysm 1 | 7
Aneurysmal disease 1 | 6
Aplasia/Hypoplasia of the abdominal wall musculature 1 | 17
Back Pain 1 | 7
Bladder Diverticulum 1 | 15
Calcium pyrophosphate deposition disease 1 | 13
Carcinoma, squamous cell of head and neck 1 | 31
Chronic diarrhea 1 | 29
Congenital hypoplasia of clavicle 1 | 18
Congenital pectus carinatum 1 | 52
Convex nasal ridge 1 | 37
Death in childhood 1 | 14
Dyslipidemias 1 | 27
Flatfoot 1 | 73
Gait, Unsteady 1 | 29
Glycosuria 1 | 29
Hair hypopigmentation 1 | 12
Hand deformities 1 | 32
Hepatitis 1 | 67
Hepatitis, Chronic 1 | 23
Hepatolenticular Degeneration 1 | 24
Hypercalciuria 1 | 27
Hyperkyphosis 1 | 111
Hyperphosphaturia 1 | 21
Hypertension, Pulmonary 1 | 37
Hypoparathyroidism 1 | 41
Hypotension, Orthostatic 1 | 18
Joint laxity 1 | 54
Joint swelling 1 | 26
Kinky hair texture 1 | 13
Kyphosis deformity of spine 1 | 114
Mask-like facies 1 | 25
Nappy hair texture 1 | 13
Narrow face 1 | 54
Pachyderma 1 | 20
Platyspondyly 1 | 56
Poor motor coordination 1 | 2
Prenatal Injuries 1 | 11
Renal tubular disorder 1 | 12
Retinopathy of prematurity 1 | 22
Sialuria 1 | 9
Soft skin 1 | 17
Steatohepatitis 1 | 44
Thin face 1 | 54
Ureteral obstruction 1 | 33
Urine phosphorous concentration above normal 1 | 21
Velvety skin 1 | 17
Venous insufficiency 1 | 9

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

Enzyme 5 | 4,145

GO Process

copper ion import 5 | 5
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Metalloreductase STEAP2 STEAP2 Tbio Enzyme -1.78852 56.5 154
Metalloreductase STEAP4 STEAP4 Tbio Enzyme -1.59030 51.2 200
Copper-transporting ATPase 2 ATP7B Tbio Enzyme -2.90950 814.5 355
Copper-transporting ATPase 1 ATP7A Tbio Enzyme -3.08069 1155.0 263
Metalloreductase STEAP3 STEAP3 Tbio Enzyme -1.40734 26.2 208