Development Level

Tbio 2 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal snout morphology 1 | 23
abnormal tail movements 1 | 12
curly tail 1 | 1
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
increased blood urea nitrogen ... 1 | 48
kinked tail 1 | 2
mammalian phenotype 1 | 17

Disease

Carcinoma 3 | 11,493
Cancer 2 | 2,499
Robinow syndrome 2 | 11
adult high grade glioma 2 | 3,801
group 3 medulloblastoma 2 | 4,104
oligodendroglioma 2 | 2,850
spina bifida 2 | 1,074
Accessory kidney 1 | 5
Angle class 2 malocclusion 1 | 57
Angle class 3 malocclusion 1 | 57
Anteverted nostril 1 | 191
Astrocytoma, Pilocytic 1 | 3,081
Bifid distal phalanx of toe 1 | 3
Bifid terminal phalanges 1 | 3
Big calvaria 1 | 147
Brachydactyly 1 | 156
Broad flat nasal bridge 1 | 236
Broad thumbs 1 | 28
Broad toes 1 | 5
Clitoral hypoplasia 1 | 11
Cognitive delay 1 | 608
Curvature of digit 1 | 57
Cystic kidney disease 1 | 26
Decreased projection of midface 1 | 105
Delayed bone age 1 | 136
Downward slant of palpebral fissure 1 | 158
Dull intelligence 1 | 645
Exophthalmos 1 | 112
Flat face 1 | 52
Frontal bossing 1 | 157
Gingival Hyperplasia 1 | 34
Gingival Hypertrophy 1 | 34
Gingival Overgrowth 1 | 36
Hernia, Inguinal 1 | 89
High forehead 1 | 102
Hydronephrosis 1 | 89
Hyperopia 1 | 70
Hypoplastic mandible condyle 1 | 275
Hypoplastic palate 1 | 4
Hypotrophic malar bone 1 | 129
Hypotrophic midface 1 | 105
Inadequate arch length for tooth size 1 | 45
Increased head circumference 1 | 147
Increased size of cranium 1 | 147
Increased size of skull 1 | 147
Late tooth eruption 1 | 61
Long palpebral fissure 1 | 17
Long philtrum 1 | 137
Macroglossia 1 | 65
Malar flattening 1 | 129
Malocclusion 1 | 57
Mental and motor retardation 1 | 608
Mesomelia 1 | 8
Midface retrusion 1 | 105
Nasal bridge wide 1 | 236
Neural Tube Defects 1 | 31
Neural Tube Defects, Susceptibility to 1 | 8
Pectus excavatum 1 | 100
Poor school performance 1 | 645
Port-Wine Stain 1 | 8
Posteriorly rotated ear 1 | 61
Pre-Eclampsia 1 | 68
Prenatal onset 1 | 139
Prominent eyes 1 | 96
Prominent globes 1 | 96
Protruding eyes 1 | 96
Radially deviated fingers 1 | 38
Short distal phalanges 1 | 50
Short hands 1 | 50
Short hard palate 1 | 4
Short middle phalanx of the 5th finger 1 | 13
Short nose 1 | 132
Short palate 1 | 4
Small labia majora 1 | 16
Small midface 1 | 105
Small nose 1 | 132
Spinal Dysraphism 1 | 12
Tall forehead 1 | 102
Tethered spinal cord syndrome 1 | 11
Thin upper lip vermilion 1 | 67
Tooth Crowding 1 | 45
Tooth mass arch size discrepancy 1 | 45
Tooth size discrepancy 1 | 45
Triangular mouth 1 | 6
Umbilical hernia 1 | 93
Ventricular Outflow Obstruction, Right 1 | 3
Wide anterior fontanel 1 | 44
astrocytic glioma 1 | 2,597
cystic fibrosis 1 | 1,696
glioblastoma 1 | 5,792
interstitial cystitis 1 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
non-small cell lung cancer 1 | 2,890
osteosarcoma 1 | 7,950
ovarian cancer 1 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pituitary cancer 1 | 1,972
primitive neuroectodermal tumor 1 | 3,035
psoriasis 1 | 6,694
subependymal giant cell astrocytoma 1 | 2,287

Tissue

Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678

Target Family

Non-IDG 3 | 12,091

GO Process

convergent extension involved ... 3 | 3
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Vang-like protein 2 VANGL2 Tbio Non-IDG -2.29322 199.6 158
Segment polarity protein dishevelled homolog DVL-2 DVL2 Tbio Non-IDG -1.87063 68.4 288
Segment polarity protein dishevelled homolog DVL-1 DVL1 Tchem Non-IDG -2.11561 188.4 169