Development Level

Tbio 6 | 11,651

IMPC Phenotype

abnormal embryo size 2 | 220
embryonic growth retardation 2 | 106
embryonic lethality prior to t... 2 | 278
preweaning lethality, complete... 2 | 979
abnormal craniofacial morpholo... 1 | 33
abnormal epididymis morphology 1 | 42
abnormal eyelid fusion 1 | 3
abnormal facial morphology 1 | 17
abnormal ovary morphology 1 | 7
absent epididymis 1 | 3
decreased blood urea nitrogen ... 1 | 51
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating glucose ... 1 | 126
decreased vertical activity 1 | 208
enlarged lymph nodes 1 | 37
hemorrhage 1 | 23
increased circulating alkaline... 1 | 122
increased circulating phosphat... 1 | 26
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
increased vertical activity 1 | 24
long tibia 1 | 25
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
shortened QT interval 1 | 4
small superior vagus ganglion 1 | 74

Disease

glioblastoma 6 | 5,792
Cancer 5 | 2,499
Intellectual disability 5 | 1,016
medulloblastoma, large-cell 5 | 6,241
Carcinoma 4 | 11,493
Dull intelligence 4 | 645
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Poor school performance 4 | 645
astrocytic glioma 4 | 2,597
ependymoma 4 | 4,679
Astrocytoma, Pilocytic 3 | 3,081
Breast cancer 3 | 3,578
Craniofacial Abnormalities 3 | 151
Downward slant of palpebral fissure 3 | 158
Epilepsy 3 | 792
Microcephaly 3 | 166
Muscle hypotonia 3 | 571
Seizures 3 | 596
atypical teratoid / rhabdoid tumor 3 | 5,112
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung cancer 3 | 4,740
malignant mesothelioma 3 | 3,232
oligodendroglioma 3 | 2,850
osteosarcoma 3 | 7,950
pediatric high grade glioma 3 | 1,064
pituitary cancer 3 | 1,972
Autistic Disorder 2 | 364
Cardiovascular Abnormalities 2 | 31
Cataract 2 | 297
Cleft Palate 2 | 271
Cognitive delay 2 | 608
Coloboma 2 | 51
Congenital ocular coloboma (disorder) 2 | 40
Ectropion 2 | 38
Failure to gain weight 2 | 365
Feeding difficulties 2 | 127
Global developmental delay 2 | 608
Hydrolethalus syndrome 2 | 128
Hypoplastic mandible condyle 2 | 275
Lens Opacities 2 | 231
Low Birth Weights 2 | 69
Low set ears 2 | 181
Mandibular hypoplasia 2 | 275
Mental and motor retardation 2 | 608
Micrognathism 2 | 275
Microphthalmia 2 | 76
Pediatric failure to thrive 2 | 365
Pick disease 2 | 1,894
Ptosis 2 | 48
Short stature 2 | 531
Small Cell Lung Carcinoma 2 | 41
Small cell carcinoma of lung 2 | 45
Small for gestational age (disorder) 2 | 69
Small head 2 | 374
Strabismus 2 | 270
Uranostaphyloschisis 2 | 167
atypical teratoid/rhabdoid tumor 2 | 357
group 3 medulloblastoma 2 | 4,104
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung carcinoma 2 | 2,843
non-small cell lung cancer 2 | 2,890
ovarian cancer 2 | 8,520
primitive neuroectodermal tumor 2 | 3,035
progressive supranuclear palsy 2 | 676
psoriasis 2 | 6,694
ADULT syndrome 1 | 9
Abnormality of the iris 1 | 14
Acute Lung Injury 1 | 22
Autistic behavior 1 | 20
Binder syndrome 1 | 3
CATARACT, AUTOSOMAL DOMINANT 1 | 4
Chromosome 2q32-q33 deletion syndrome 1 | 5
Coloboma of eyelid 1 | 15
Coloboma of lens 1 | 4
Coloboma of macula 1 | 4
Coloboma of optic disc 1 | 9
Congenital coloboma of iris 1 | 4
Generalized hyperpigmentation 1 | 22
Goldenhar syndrome 1 | 20
Hereditary macular coloboma 1 | 5
Long nose 1 | 15
Missing more than six teeth 1 | 22
Optic disc abnormalities 1 | 12
Peg-shaped teeth 1 | 8
Persistent hyperplastic primary vitreous 1 | 20
Pointed teeth 1 | 8
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1 | 25
Pulmonary alveolar proteinosis 1 | 15
Recurrent fungal infections 1 | 13
Recurrent viral infections 1 | 15
Reduced visual acuity 1 | 63
Renal coloboma syndrome 1 | 4
Sleeping sickness 1 | 37
Small face 1 | 10
Waardenburg's syndrome 1 | 17

Tissue

Endocrine System 6 | 18,159
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Blood and immune system 5 | 16,909
Digestive Tract 5 | 17,369
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678
Cardiovascular System 3 | 15,192

Target Family

Transcription Factor 6 | 1,400

GO Process

commitment of neuronal cell to... 6 | 6
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA-binding protein SATB2 SATB2 Tbio Transcription Factor -2.88608 726.3 200
Endothelial transcription factor GATA-2 GATA2 Tbio Transcription Factor -2.70355 475.5 354
Achaete-scute homolog 1 ASCL1 Tbio Transcription Factor -2.44791 277.6 405
Paired box protein Pax-6 PAX6 Tbio Transcription Factor -3.16650 1458.6 570
B-cell lymphoma/leukemia 11B BCL11B Tbio Transcription Factor -2.10918 140.4 186
T-box brain protein 1 TBR1 Tbio Transcription Factor -1.86637 67.2 146