Development Level

Tbio 3 | 11,445
Tclin 2 | 613
Tchem 1 | 1,598

IMPC Phenotype

abnormal behavior 1 | 298
abnormal lens morphology 1 | 81
cataract 1 | 92
enlarged adrenal glands 1 | 3
enlarged kidney 1 | 14
enlarged uterus 1 | 11
hydrometra 1 | 53
increased fasted circulating g... 1 | 76
irregularly shaped pupil 1 | 7
polycystic kidney 1 | 15

Disease

Cancer 5 | 2,499
Carcinoma 5 | 11,493
atypical teratoid / rhabdoid tumor 4 | 5,112
lung cancer 4 | 4,740
ovarian cancer 4 | 8,520
Astrocytoma, Pilocytic 3 | 3,081
Intellectual disability 3 | 1,016
adult high grade glioma 3 | 3,801
astrocytoma 3 | 1,146
group 4 medulloblastoma 3 | 1,855
interstitial cystitis 3 | 2,312
lung adenocarcinoma 3 | 2,716
medulloblastoma, large-cell 3 | 6,241
oligodendroglioma 3 | 2,850
osteosarcoma 3 | 7,950
Alzheimer's disease 2 | 658
Amyotrophic lateral sclerosis 2 | 451
Big calvaria 2 | 147
Breast Neoplasms 2 | 445
Cryptorchidism 2 | 296
Depressive disorder 2 | 409
Down syndrome 2 | 499
Downward slant of palpebral fissure 2 | 158
Dull intelligence 2 | 645
Epilepsy 2 | 792
Frontal bossing 2 | 157
Heart Defects, Congenital 2 | 37
Hypoplastic mandible condyle 2 | 275
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Kidney cancer 2 | 2,613
Late tooth eruption 2 | 61
Low intelligence 2 | 645
Low set ears 2 | 181
Mammary Neoplasms 2 | 425
Mandibular hypoplasia 2 | 275
Mental Depression 2 | 333
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Micrognathism 2 | 275
Pectus excavatum 2 | 100
Poor school performance 2 | 645
Posteriorly rotated ear 2 | 61
Short hands 2 | 50
Short nose 2 | 132
Short stature 2 | 531
Small nose 2 | 132
breast carcinoma 2 | 1,638
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
juvenile dermatomyositis 2 | 1,187
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
pancreatic cancer 2 | 2,398
primitive neuroectodermal tumor 2 | 3,035
psoriasis 2 | 6,694
tuberculosis 2 | 2,010
Angle class 2 malocclusion 1 | 57
Angle class 3 malocclusion 1 | 57
Blastic phase chronic myeloid leukemia 1 | 58
Bone Diseases, Developmental 1 | 27
Bulimia nervosa 1 | 14
Carcinogenesis 1 | 8
Cardiovascular Abnormalities 1 | 31
Cell Transformation, Neoplastic 1 | 97
Chronic Myelocytic Leukemia Accelerated Phase 1 | 59
Chronic phase chronic myeloid leukemia 1 | 45
Clitoral hypoplasia 1 | 11
Congenital pectus carinatum 1 | 52
Dermatofibrosarcoma protuberans 1 | 15
Diabetic retinopathy 1 | 56
Eating disorder 1 | 26
Everted lower lip vermilion 1 | 54
Gastrointestinal stromal tumor 1 | 62
Long palpebral fissure 1 | 17
Malocclusion 1 | 57
Mild Mental Retardation 1 | 70
Mowat-Wilson syndrome 1 | 11
Musculoskeletal Abnormalities 1 | 6
Neoplasms, Experimental 1 | 40
Neoplastic Cell Transformation 1 | 89
Opiate dependence 1 | 29
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 1 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 1 | 47
Platyspondyly 1 | 56
Precancerous Conditions 1 | 80
Protruding lower lip 1 | 54
Rett syndrome 1 | 18
Robinow syndrome 1 | 11
Short distal phalanges 1 | 50
Substance Withdrawal Syndrome 1 | 55
Substance abuse 1 | 59
Thyroid cancer, papillary 1 | 14
Ventricular Outflow Obstruction, Right 1 | 3
Widely spaced teeth 1 | 31
acute T cell leukemia 1 | 17

Tissue

Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678

Target Family

Non-IDG 3 | 12,091
Epigenetic 1 | 242
Kinase 1 | 634
Transcription Factor 1 | 1,400

GO Process

collateral sprouting 6 | 6
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Brain-derived neurotrophic factor BDNF Tbio Non-IDG -4.00507 10701.6 723
Zinc finger E-box-binding homeobox 2 ZEB2 Tbio Transcription Factor -2.49656 262.6 474
Tyrosine-protein kinase ABL1 ABL1 Tclin Kinase -3.51854 3418.5 1661
Ephrin-A5 EFNA5 Tbio Non-IDG -2.57120 355.6 202
Segment polarity protein dishevelled homolog DVL-1 DVL1 Tchem Non-IDG -2.11561 188.4 169
Histone deacetylase 6 HDAC6 Tclin Epigenetic -2.72354 545.3 725