Development Level

Tbio 9 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal limb position 1 | 3
abnormal pericardium morpholog... 1 | 26
abnormal skin morphology 1 | 50
abnormal thoracic cage shape 1 | 3
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating glycerol... 1 | 16
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased mean corpuscular hem... 1 | 50
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged spleen 1 | 41
increased mean corpuscular hem... 1 | 96
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979
prolonged RR interval 1 | 8
thin skin 1 | 2

Disease

Carcinoma 8 | 11,493
osteosarcoma 8 | 7,950
ovarian cancer 8 | 8,520
psoriasis 6 | 6,694
glioblastoma 5 | 5,792
non-small cell lung cancer 5 | 2,890
Astrocytoma, Pilocytic 4 | 3,081
Autosomal recessive predisposition 4 | 1,442
breast carcinoma 4 | 1,638
ductal carcinoma in situ 4 | 1,745
invasive ductal carcinoma 4 | 2,951
lung adenocarcinoma 4 | 2,716
lung cancer 4 | 4,740
lung carcinoma 4 | 2,843
Cancer 3 | 2,499
adult high grade glioma 3 | 3,801
atypical teratoid / rhabdoid tumor 3 | 5,112
interstitial cystitis 3 | 2,312
medulloblastoma, large-cell 3 | 6,241
ulcerative colitis 3 | 1,819
ARC syndrome 2 | 13
Arthrogryposis renal dysfunction cholestasis syndrome 2 | 2
Bipolar Disorder 2 | 666
Breast cancer 2 | 3,578
Cataract 2 | 297
Cholestasis 2 | 155
Cognitive delay 2 | 608
Degenerative polyarthritis 2 | 115
Depressive disorder 2 | 409
Ecchymosis 2 | 66
Ehlers-Danlos syndrome 2 | 43
Global developmental delay 2 | 608
Ichthyosis 2 | 56
Increased tendency to bruise 2 | 66
Kidney cancer 2 | 2,613
Lens Opacities 2 | 231
Liver cancer 2 | 604
Low set ears 2 | 181
Major Depressive Disorder 2 | 301
Mental Depression 2 | 333
Mental and motor retardation 2 | 608
Mood Disorders 2 | 184
Multiple Sclerosis 2 | 540
Muscle hypotonia 2 | 571
Myopia 2 | 176
Rheumatoid arthritis 2 | 1,191
Spinal Cord Injuries 2 | 8
Vascular disease 2 | 319
astrocytoma 2 | 1,146
cystic fibrosis 2 | 1,696
ependymoma 2 | 4,679
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
malignant mesothelioma 2 | 3,232
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
pituitary cancer 2 | 1,972
tuberculosis 2 | 2,010
Acquired flat foot 1 | 72
Acute cystitis 1 | 35
Alopecia areata 1 | 41
Auricular malformation 1 | 41
Bicornuate uterus 1 | 11
Biliary cirrhosis 1 | 45
CD40 deficiency 1 | 4
Cellulitis 1 | 20
Choanal Atresia 1 | 42
Conjugated hyperbilirubinemia 1 | 14
Cystinuria 1 | 18
Dehydration 1 | 40
Diaphragmatic eventration 1 | 11
Flatfoot 1 | 73
Hypertension, Pulmonary 1 | 37
Idiopathic pulmonary fibrosis 1 | 23
Increased calcium level in kidney 1 | 21
Liver Cirrhosis, Biliary 1 | 33
Mitral Valve Prolapse Syndrome 1 | 39
Myocardial Reperfusion Injury 1 | 37
Neoplasms 1 | 63
Nephrotic Syndrome 1 | 78
Osteogenesis imperfecta type III (disorder) 1 | 11
Pharyngitis 1 | 17
Platyspondyly 1 | 56
Pleural empyema 1 | 12
Pyelonephritis 1 | 13
Radiation Injuries, Experimental 1 | 11
Shallow orbits 1 | 13
Simple ear 1 | 41
Skin Neoplasms 1 | 69
Small cell carcinoma of lung 1 | 45
Soft skin 1 | 17
Thyroid Neoplasm 1 | 37
Thyroid Neoplasms 1 | 34
Tonsillitis 1 | 16
Type 1 diabetes mellitus 1 | 109
Ullrich congenital muscular dystrophy 1 | 5
Velvety skin 1 | 17
Vesico-Ureteral Reflux 1 | 33
Vesicoureteral reflux 1 | 32
osteogenesis imperfecta type 3 1 | 11

Tissue

Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678

Target Family

Enzyme 5 | 4,145
Non-IDG 3 | 12,091
Transcription Factor 2 | 1,400
Ion Channel 1 | 344

GO Process

collagen metabolic process 11 | 11
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Prolyl 3-hydroxylase 2 P3H2 Tbio Enzyme -2.49306 295.2 60
Vacuolar protein sorting-associated protein 33B VPS33B Tbio Non-IDG -1.54312 36.3 34
Tensin-2 TNS2 Tbio Enzyme -1.46509 30.5 50
Spermatogenesis-defective protein 39 homolog VIPAS39 Tbio Non-IDG -1.44333 27.2 68
DNA-binding protein inhibitor ID-1 ID1 Tbio Transcription Factor -2.62261 440.3 311
P2X purinoceptor 7 P2RX7 Tchem Ion Channel -2.96940 962.2 272
Prolyl 3-hydroxylase 3 P3H3 Tbio Enzyme -1.97511 85.0 71
Prolyl 3-hydroxylase 1 P3H1 Tbio Enzyme -1.47252 31.3 199
Hypoxia-inducible factor 1-alpha HIF1A Tchem Transcription Factor -3.47924 3234.0 1450
Tenascin-X TNXB Tbio Non-IDG -2.42973 259.1 126