Development Level

Tbio 35 | 11,445
Tchem 5 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal tail morphology 2 | 25
embryonic lethality prior to t... 2 | 278
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal pericardium morpholog... 1 | 26
abnormal skin coloration 1 | 25
abnormal tail movements 1 | 12
abnormal thoracic cage shape 1 | 3
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
dilated heart left ventricle 1 | 11
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
enlarged spleen 1 | 41
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased startle reflex 1 | 112
kinked tail 1 | 2
mammalian phenotype 1 | 17
prenatal lethality prior to he... 1 | 87

Disease

ovarian cancer 32 | 8,520
Carcinoma 31 | 11,493
osteosarcoma 24 | 7,950
pancreatic cancer 24 | 2,398
Breast cancer 23 | 3,578
glioblastoma 23 | 5,792
Astrocytoma, Pilocytic 22 | 3,081
lung cancer 22 | 4,740
ependymoma 20 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
psoriasis 19 | 6,694
Kidney cancer 18 | 2,613
adult high grade glioma 18 | 3,801
atypical teratoid / rhabdoid tumor 18 | 5,112
lung adenocarcinoma 18 | 2,716
medulloblastoma, large-cell 18 | 6,241
Cancer 17 | 2,499
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
non-small cell lung cancer 17 | 2,890
Duchenne muscular dystrophy 15 | 601
cystic fibrosis 15 | 1,696
group 3 medulloblastoma 15 | 4,104
pituitary cancer 15 | 1,972
subependymal giant cell astrocytoma 15 | 2,287
gastric carcinoma 14 | 807
primary pancreatic ductal adenocarcinoma 14 | 1,109
Autosomal recessive predisposition 13 | 1,442
Ehlers-Danlos syndrome 13 | 43
Myopia 13 | 176
malignant mesothelioma 13 | 3,232
ulcerative colitis 13 | 1,819
Acquired scoliosis 12 | 281
Curvature of spine 12 | 282
Hypoplastic mandible condyle 12 | 275
Mandibular hypoplasia 12 | 275
Micrognathism 12 | 275
Short stature 12 | 531
breast carcinoma 12 | 1,638
ductal carcinoma in situ 12 | 1,745
interstitial cystitis 12 | 2,312
invasive ductal carcinoma 12 | 2,951
primitive neuroectodermal tumor 12 | 3,035
Ecchymosis 11 | 66
Hypotrophic malar bone 11 | 129
Increased tendency to bruise 11 | 66
Liver Cirrhosis, Experimental 11 | 769
Malar flattening 11 | 129
adrenocortical carcinoma 11 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 11 | 510
juvenile dermatomyositis 11 | 1,187
lung carcinoma 11 | 2,843
Hernia, Inguinal 10 | 89
Joint hyperflexibility 10 | 78
oligodendroglioma 10 | 2,850
Acquired flat foot 9 | 72
Becker muscular dystrophy 9 | 191
Decreased projection of midface 9 | 105
Degenerative polyarthritis 9 | 115
Flatfoot 9 | 73
Hypotrophic midface 9 | 105
Liver Cirrhosis 9 | 181
Melanoma 9 | 711
Midface retrusion 9 | 105
Orbital separation excessive 9 | 244
Platyspondyly 9 | 56
Small midface 9 | 105
esophageal adenocarcinoma 9 | 737
limb girdle muscular dystrophy 2A 9 | 213
nasopharyngeal carcinoma 9 | 1,058
urothelial carcinoma 9 | 318
Atopic dermatitis 8 | 952
Exophthalmos 8 | 112
Glaucoma 8 | 239
Mitral Valve Prolapse Syndrome 8 | 39
Muscle hypotonia 8 | 571
Pectus excavatum 8 | 100
Pick disease 8 | 1,894
Skin cancer 8 | 469
interstitial lung disease 8 | 298
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Blue sclera 7 | 32
Cataract 7 | 297
Cognitive delay 7 | 608
Congenital Epicanthus 7 | 177
Global developmental delay 7 | 608
Mental and motor retardation 7 | 608
Osteoarthritis 7 | 184
Prominent eyes 7 | 96
Prominent globes 7 | 96
Protruding eyes 7 | 96
Respiratory Insufficiency 7 | 132
Respiratory function loss 7 | 121
Skin hyperelastic 7 | 32
Soft skin 7 | 17
Velvety skin 7 | 17
acute quadriplegic myopathy 7 | 1,158
astrocytoma 7 | 1,146
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
astrocytic glioma 6 | 2,597
colon cancer 6 | 1,478

Tissue

Digestive Tract 40 | 17,369
Endocrine System 40 | 18,159
Female tissues 40 | 17,400
Liver and Pancreas 40 | 16,750
Male tissues 40 | 17,142
Nervous System 40 | 16,725
Skin and soft tissues 40 | 17,230
Blood and immune system 39 | 16,909
Respiratory system 39 | 16,393
Urinary Tract 39 | 16,678
Cardiovascular System 37 | 15,192

Target Family

Non-IDG 28 | 12,091
Enzyme 8 | 4,145
Transcription Factor 3 | 1,400
Kinase 2 | 634

GO Process

collagen fibril organization 41 | 41
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Forkhead box protein C2 FOXC2 Tbio Transcription Factor -2.23435 187.0 419
A disintegrin and metalloproteinase with thrombospondin motifs 14 ADAMTS14 Tbio Enzyme -0.89572 7.58 29
Collagen alpha-1(XII) chain COL12A1 Tbio Non-IDG -1.36571 21.4 38
Collagen alpha-1(XI) chain COL11A1 Tbio Non-IDG -2.15516 138.4 96
A disintegrin and metalloproteinase with thrombospondin motifs 3 ADAMTS3 Tbio Enzyme -0.75603 4.50 45
Serpin H1 SERPINH1 Tbio Non-IDG -3.18763 1526.9 346
Collagen alpha-2(V) chain COL5A2 Tbio Non-IDG -1.69982 44.6 96
Dermatopontin DPT Tbio Non-IDG -3.11590 1302.1 89
Basic helix-loop-helix transcription factor scleraxis SCX Tbio Transcription Factor -2.84150 362.9 46
Collagen alpha-2(XI) chain COL11A2 Tbio Non-IDG -1.89476 73.6 143