Development Level

Tbio 37 | 11,445
Tchem 25 | 1,598
Tdark 3 | 6,588

IMPC Phenotype

decreased total body fat amoun... 3 | 207
abnormal skin coloration 2 | 25
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
short tibia 2 | 97
abnormal behavior 1 | 298
abnormal esophagus morphology 1 | 5
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal pancreas morphology 1 | 13
abnormal tail morphology 1 | 25
abnormal thyroid gland morphol... 1 | 3
abnormal trachea morphology 1 | 3
abnormal vibrissa morphology 1 | 25
absent lymph nodes 1 | 3
anophthalmia 1 | 33
athymia 1 | 2
brachydactyly 1 | 19
decreased T cell number 1 | 15
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
dilated heart left ventricle 1 | 11
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased CD4-positive, CD25-p... 1 | 1
increased KLRG1-positive NK ce... 1 | 1
increased NK cell number 1 | 3
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased circulating triglyce... 1 | 42
increased effector memory CD4-... 1 | 1
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased large unstained cell... 1 | 5
increased mean corpuscular hem... 1 | 36
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
increased vertical activity 1 | 24
persistence of hyaloid vascula... 1 | 33
premature death 1 | 5
small superior vagus ganglion 1 | 74

Disease

Carcinoma 56 | 11,493
ovarian cancer 41 | 8,520
glioblastoma 31 | 5,792
Astrocytoma, Pilocytic 30 | 3,081
pancreatic cancer 30 | 2,398
psoriasis 30 | 6,694
Breast cancer 29 | 3,578
atypical teratoid / rhabdoid tumor 29 | 5,112
lung cancer 28 | 4,740
non-small cell lung cancer 28 | 2,890
osteosarcoma 28 | 7,950
lung adenocarcinoma 27 | 2,716
Cancer 25 | 2,499
Kidney cancer 25 | 2,613
cystic fibrosis 25 | 1,696
ependymoma 25 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,955
malignant mesothelioma 24 | 3,232
adult high grade glioma 23 | 3,801
invasive ductal carcinoma 23 | 2,951
ulcerative colitis 23 | 1,819
gastric carcinoma 22 | 807
interstitial cystitis 22 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,989
medulloblastoma, large-cell 21 | 6,241
pituitary cancer 20 | 1,972
Autosomal recessive predisposition 19 | 1,442
breast carcinoma 18 | 1,638
nasopharyngeal carcinoma 18 | 1,058
Duchenne muscular dystrophy 17 | 601
Liver Cirrhosis, Experimental 17 | 769
ductal carcinoma in situ 17 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
lung carcinoma 17 | 2,843
primitive neuroectodermal tumor 15 | 3,035
subependymal giant cell astrocytoma 15 | 2,287
Abortion, Spontaneous 14 | 109
Short stature 14 | 531
Spontaneous abortion 14 | 113
group 3 medulloblastoma 14 | 4,104
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
primary pancreatic ductal adenocarcinoma 14 | 1,109
Skin cancer 13 | 469
autosomal dominant Emery-Dreifuss muscular dystrophy 13 | 510
periodontitis 13 | 293
urothelial carcinoma 13 | 318
Becker muscular dystrophy 12 | 191
Hypoplastic mandible condyle 12 | 275
Mandibular hypoplasia 12 | 275
Melanoma 12 | 711
Micrognathism 12 | 275
adrenocortical carcinoma 12 | 1,428
cutaneous lupus erythematosus 12 | 1,057
esophageal adenocarcinoma 12 | 737
head and neck cancer and chronic obstructive pulmonary disease 12 | 239
juvenile dermatomyositis 12 | 1,187
Acquired scoliosis 11 | 281
Atopic dermatitis 11 | 952
Curvature of spine 11 | 282
Degenerative polyarthritis 11 | 115
diabetes mellitus 11 | 1,728
interstitial lung disease 11 | 298
Arthritis 10 | 290
Dental caries 10 | 164
Kidney disease 10 | 430
Myopia 10 | 176
Vascular disease 10 | 319
colon cancer 10 | 1,478
oligodendroglioma 10 | 2,850
Ehlers-Danlos syndrome 9 | 43
Exophthalmos 9 | 112
Liver cancer 9 | 604
Osteoarthritis 9 | 184
Osteoporosis 9 | 363
Respiratory Insufficiency 9 | 132
Respiratory function loss 9 | 121
limb girdle muscular dystrophy 2A 9 | 213
tuberculosis 9 | 2,010
Congenital deafness 8 | 185
Contracture 8 | 96
Contracture of joint 8 | 93
Deafness 8 | 198
Degenerative disc disease 8 | 35
Flexion contracture 8 | 93
Flexion contractures of joints 8 | 93
Hearing Loss, Partial 8 | 185
Hyperkyphosis 8 | 111
Joint stiffness 8 | 84
Kyphosis deformity of spine 8 | 114
Neoplasm Invasiveness 8 | 161
Prominent eyes 8 | 96
Prominent globes 8 | 96
Protruding eyes 8 | 96
Rheumatoid arthritis 8 | 1,191
acute quadriplegic myopathy 8 | 1,158
astrocytoma 8 | 1,146
hearing impairment 8 | 199
primary Sjogren syndrome 8 | 735
pterygium 8 | 76
Pick disease 7 | 1,894

Tissue

Female tissues 65 | 17,400
Digestive Tract 64 | 17,369
Blood and immune system 63 | 16,909
Endocrine System 62 | 18,159
Male tissues 62 | 17,142
Skin and soft tissues 62 | 17,230
Urinary Tract 61 | 16,678
Liver and Pancreas 60 | 16,750
Respiratory system 59 | 16,393
Nervous System 57 | 16,725
Cardiovascular System 52 | 15,192

Target Family

Non-IDG 35 | 12,091
Enzyme 30 | 4,145

GO Process

collagen catabolic process 65 | 65
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
A disintegrin and metalloproteinase with thrombospondin motifs 14 ADAMTS14 Tbio Enzyme -0.89572 7.58 29
Collagen alpha-1(XII) chain COL12A1 Tbio Non-IDG -1.36571 21.4 38
Disintegrin and metalloproteinase domain-containing protein 15 ADAM15 Tbio Enzyme -1.87408 84.1 301
Collagen alpha-1(XV) chain COL15A1 Tbio Non-IDG -1.18716 15.5 74
Collagen alpha-1(XVIII) chain COL18A1 Tbio Non-IDG -3.18339 1561.4 433
Collagen alpha-1(VI) chain COL6A1 Tbio Non-IDG -2.03348 104.7 204
Collagen alpha-1(XI) chain COL11A1 Tbio Non-IDG -2.15516 138.4 96
Collagen alpha-2(VI) chain COL6A2 Tbio Non-IDG -1.80531 59.2 151
A disintegrin and metalloproteinase with thrombospondin motifs 3 ADAMTS3 Tbio Enzyme -0.75603 4.50 45
Collagen alpha-1(IV) chain COL4A1 Tbio Non-IDG -2.28595 186.9 391