Development Level

Tbio 21 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

mammalian phenotype 2 | 17
preweaning lethality, incomple... 2 | 499
abnormal behavioral response t... 1 | 66
abnormal locomotor activation 1 | 16
abnormal response to new envir... 1 | 10
abnormal snout morphology 1 | 23
abnormal tail movements 1 | 12
convulsive seizures 1 | 13
curly tail 1 | 1
decreased IgE level 1 | 6
decreased blood urea nitrogen ... 1 | 51
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased leukocyte cell numbe... 1 | 73
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased blood urea nitrogen ... 1 | 48
increased circulating calcium ... 1 | 34
increased circulating glucose ... 1 | 24
increased heart weight 1 | 62
increased urine magnesium leve... 1 | 2
kinked tail 1 | 2
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 19 | 11,493
psoriasis 13 | 6,694
Cancer 12 | 2,499
Breast cancer 11 | 3,578
medulloblastoma, large-cell 11 | 6,241
ovarian cancer 11 | 8,520
ependymoma 10 | 4,679
osteosarcoma 10 | 7,950
adult high grade glioma 9 | 3,801
glioblastoma 9 | 5,792
atypical teratoid / rhabdoid tumor 8 | 5,112
group 3 medulloblastoma 8 | 4,104
non-small cell lung cancer 8 | 2,890
astrocytic glioma 7 | 2,597
cystic fibrosis 7 | 1,696
interstitial cystitis 7 | 2,312
pancreatic cancer 7 | 2,398
Astrocytoma, Pilocytic 6 | 3,081
Orbital separation excessive 6 | 244
invasive ductal carcinoma 6 | 2,951
oligodendroglioma 6 | 2,850
primitive neuroectodermal tumor 6 | 3,035
Cleft Palate 5 | 271
Cognitive delay 5 | 608
Congenital hypoplasia of penis 5 | 176
Craniofacial Abnormalities 5 | 151
Cryptorchidism 5 | 296
Dull intelligence 5 | 645
Global developmental delay 5 | 608
Hypotrophic malar bone 5 | 129
Intellectual disability 5 | 1,016
Low intelligence 5 | 645
Malar flattening 5 | 129
Mental Retardation 5 | 645
Mental and motor retardation 5 | 608
Mental deficiency 5 | 645
Poor school performance 5 | 645
breast carcinoma 5 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
lung adenocarcinoma 5 | 2,716
lung cancer 5 | 4,740
malignant mesothelioma 5 | 3,232
primary pancreatic ductal adenocarcinoma 5 | 1,109
Cleft uvula 4 | 27
Concave bridge of nose 4 | 195
Conductive hearing loss 4 | 123
Congenital Heart Defects 4 | 58
Decreased projection of midface 4 | 105
Depressed nasal bridge 4 | 195
Depressed nasal root/bridge 4 | 195
Exophthalmos 4 | 112
Highly variable severity 4 | 157
Hydronephrosis 4 | 89
Hypoplastic mandible condyle 4 | 275
Hypotrophic midface 4 | 105
Long philtrum 4 | 137
Low set ears 4 | 181
Mandibular hypoplasia 4 | 275
Micrognathism 4 | 275
Midface retrusion 4 | 105
Nonsyndromic deafness 4 | 142
Prominent eyes 4 | 96
Prominent globes 4 | 96
Protruding eyes 4 | 96
RENAL ADYSPLASIA 4 | 25
Renal dysplasia 4 | 28
Robinow syndrome 4 | 11
Sensorineural Hearing Loss (disorder) 4 | 284
Short stature 4 | 531
Small midface 4 | 105
Uranostaphyloschisis 4 | 167
Variable expressivity 4 | 157
ductal carcinoma in situ 4 | 1,745
pituitary cancer 4 | 1,972
Anteverted nostril 3 | 191
Atopic dermatitis 3 | 952
Autosomal recessive predisposition 3 | 1,442
Broad flat nasal bridge 3 | 236
Delayed bone age 3 | 136
Epilepsy 3 | 792
Flat face 3 | 52
Frontal bossing 3 | 157
Hernia, Inguinal 3 | 89
High forehead 3 | 102
Kidney cancer 3 | 2,613
Nasal bridge wide 3 | 236
Seizures 3 | 596
Umbilical hernia 3 | 93
colon cancer 3 | 1,478
gastric carcinoma 3 | 807
lung carcinoma 3 | 2,843
nasopharyngeal carcinoma 3 | 1,058
nephrosclerosis 3 | 333
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pediatric high grade glioma 3 | 1,064
sonic hedgehog group medulloblastoma 3 | 467
spina bifida 3 | 1,074
tuberculosis 3 | 2,010
ulcerative colitis 3 | 1,819

Tissue

Endocrine System 22 | 18,159
Female tissues 22 | 17,400
Urinary Tract 22 | 16,678
Blood and immune system 21 | 16,909
Digestive Tract 21 | 17,369
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Skin and soft tissues 21 | 17,230
Nervous System 20 | 16,725
Respiratory system 20 | 16,393
Cardiovascular System 15 | 15,192

Target Family

Transcription Factor 10 | 1,400
Non-IDG 9 | 12,091
Kinase 3 | 634
Enzyme 1 | 4,145
GPCR 1 | 408

GO Process

cochlea morphogenesis 24 | 24
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myosin-IIIb MYO3B Tbio Kinase -0.73450 5.14 127
T-box transcription factor TBX1 TBX1 Tbio Transcription Factor -1.99519 95.5 207
TRAF-interacting protein with FHA domain-containing protein B TIFAB Tbio Non-IDG -0.55328 2.93 54
Paired box protein Pax-2 PAX2 Tbio Transcription Factor -2.68609 492.0 349
Serine protease hepsin HPN Tchem Enzyme -2.50023 316.0 125
POU domain, class 3, transcription factor 4 POU3F4 Tbio Transcription Factor -2.27006 184.7 62
Zinc finger E-box-binding homeobox 1 ZEB1 Tbio Transcription Factor -2.88752 659.2 460
Collagen triple helix repeat-containing protein 1 CTHRC1 Tbio Non-IDG -1.72221 62.3 202
Myosin-IIIa MYO3A Tbio Kinase -1.25280 20.1 130
Dendritic cell nuclear protein 1 DCANP1 Tbio Non-IDG -0.72016 5.94 28