Development Level

Tbio 18 | 11,445
Tchem 2 | 1,598
Tdark 2 | 6,588

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal cecum morphology 1 | 7
abnormal eating behavior 1 | 1
abnormal embryo size 1 | 220
abnormal forced expiratory flo... 1 | 1
abnormal heart morphology 1 | 162
abnormal heart shape 1 | 5
abnormal lens morphology 1 | 81
abnormal seminal vesicle morph... 1 | 114
abnormal whole-body plethysmog... 1 | 4
absent pinna reflex 1 | 23
altered righting response 1 | 1
decreased body temperature 1 | 2
decreased body weight 1 | 161
decreased circulating creatini... 1 | 39
decreased mean platelet volume 1 | 25
decreased tidal volume 1 | 1
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged cecum 1 | 5
enlarged heart 1 | 210
enlarged seminal vesicle 1 | 10
hydrometra 1 | 53
increased blood urea nitrogen ... 1 | 48
increased circulating free fat... 1 | 20
increased circulating iron lev... 1 | 30
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
persistence of hyaloid vascula... 1 | 33
small superior vagus ganglion 1 | 74

Disease

Carcinoma 17 | 11,493
ovarian cancer 15 | 8,520
psoriasis 12 | 6,694
osteosarcoma 11 | 7,950
medulloblastoma, large-cell 10 | 6,241
ependymoma 9 | 4,679
glioblastoma 9 | 5,792
atypical teratoid / rhabdoid tumor 7 | 5,112
group 3 medulloblastoma 7 | 4,104
oligodendroglioma 7 | 2,850
diabetes mellitus 6 | 1,728
Astrocytoma, Pilocytic 5 | 3,081
Breast cancer 5 | 3,578
Cataract 8 multiple types 5 | 33
Multiple myeloma 5 | 1,332
adrenocortical carcinoma 5 | 1,428
adult high grade glioma 5 | 3,801
pancreatic cancer 5 | 2,398
acute quadriplegic myopathy 4 | 1,158
astrocytic glioma 4 | 2,597
lung carcinoma 4 | 2,843
malignant mesothelioma 4 | 3,232
primitive neuroectodermal tumor 4 | 3,035
spina bifida 4 | 1,074
subependymal giant cell astrocytoma 4 | 2,287
Cancer 3 | 2,499
Down syndrome 3 | 499
Familial hypocalciuric hypercalcemia 3 | 20
Rheumatoid arthritis 3 | 1,191
astrocytoma 3 | 1,146
esophageal adenocarcinoma 3 | 737
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
juvenile dermatomyositis 3 | 1,187
lung adenocarcinoma 3 | 2,716
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,109
Chronic Lymphocytic Leukemia 2 | 262
Kidney cancer 2 | 2,613
Leber congenital amaurosis 2 | 69
Parkinson's disease 2 | 392
Pick disease 2 | 1,894
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 922
acute myeloid leukemia 2 | 783
aldosterone-producing adenoma 2 | 665
atypical teratoid/rhabdoid tumor 2 | 357
dermatomyositis 2 | 966
group 4 medulloblastoma 2 | 1,855
interstitial lung disease 2 | 298
lung cancer 2 | 4,740
mucosa-associated lymphoid tissue lymphoma 2 | 484
non-small cell lung cancer 2 | 2,890
Alobar Holoprosencephaly 1 | 14
Alzheimer Disease 1 | 83
Anemia 1 | 365
Arthrogryposis 1 | 54
Breast Neoplasms 1 | 445
Choreatic disease 1 | 52
Chronic tic disorder 1 | 8
Coronary artery disease 1 | 268
Dementia 1 | 175
Diarrhea 1 | 253
Endocarditis 1 | 19
Gaucher disease type 1 1 | 180
Hereditary spherocytosis type 4 1 | 18
Huntington's disease 1 | 76
Leukemia, Acute Myeloid 1 | 17
Leukemia, Myelocytic, Acute 1 | 120
Lipoma 1 | 32
Liver Cirrhosis, Experimental 1 | 769
Liver cancer 1 | 604
Lung Neoplasms 1 | 232
Mammary Neoplasms 1 | 425
Neuroacanthocytosis 1 | 6
Neurodegenerative disease 1 | 414
Neurogenic Muscular Atrophy 1 | 139
Neurogenic bladder 1 | 16
Neurogenic muscle atrophy, especially in the lower limbs 1 | 139
Neutropenia 1 | 72
Oculocutaneous albinism 1 | 29
Pain agnosia 1 | 104
Parkinson Disease 1 | 64
Pilocytic astrocytoma 1 | 56
Renal Cell Carcinoma 1 | 214
Respiratory Insufficiency 1 | 132
Respiratory function loss 1 | 121
Semilobar Holoprosencephaly 1 | 14
Skeletal muscle atrophy 1 | 139
Teratocarcinoma 1 | 8
Wolff-Parkinson-White syndrome 1 | 19
active ulcerative colitis 1 | 764
dentatorubral-pallidoluysian atrophy 1 | 21
facioscapulohumeral dystrophy 1 | 288
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
hereditary spastic paraplegia 1 | 318
muscle degeneration 1 | 139
non-small cell lung carcinoma 1 | 317
posterior fossa group A ependymoma 1 | 468
posterior fossa group B ependymoma 1 | 416
uncontrolled asthma 1 | 56

Tissue

Blood and immune system 21 | 16,909
Cardiovascular System 21 | 15,192
Digestive Tract 21 | 17,369
Endocrine System 21 | 18,159
Female tissues 21 | 17,400
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Nervous System 21 | 16,725
Respiratory system 21 | 16,393
Skin and soft tissues 21 | 17,230
Urinary Tract 21 | 16,678

Target Family

Non-IDG 17 | 12,091
Kinase 2 | 634
Enzyme 1 | 4,145
GPCR 1 | 408
Transporter 1 | 473

GO Process

clathrin-dependent endocytosis 22 | 22
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium/hydrogen exchanger 9B2 SLC9B2 Tbio Transporter -1.21956 18.8 126
Clathrin heavy chain 1 CLTC Tbio Non-IDG -1.66258 38.8 231
Huntingtin-interacting protein 1 HIP1 Tbio Non-IDG -1.73638 55.9 202
F-BAR domain only protein 2 FCHO2 Tbio Non-IDG -0.65144 5.00 106
Clathrin light chain A CLTA Tbio Non-IDG -1.32676 16.0 244
Clathrin light chain B CLTB Tbio Non-IDG -2.29105 193.6 153
Cyclin-G-associated kinase GAK Tchem Kinase -1.85747 68.2 231
Formin-binding protein 1-like FNBP1L Tbio Non-IDG -1.58385 34.7 142
Putative GED domain-containing protein DNM1P34 DNM1P34 Tdark Non-IDG 0.00000 0
Phosphatidylinositide phosphatase SAC2 INPP5F Tbio Enzyme -0.71120 5.56 89