Development Level

Tbio 43 | 11,445
Tchem 17 | 1,598
Tclin 13 | 613
Tdark 1 | 6,588

Collection

GPCR: IDG Consortium (Targets) 2 | 126
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 5 | 979
preweaning lethality, incomple... 5 | 499
abnormal behavior 4 | 298
hyperactivity 4 | 148
abnormal embryo size 3 | 220
decreased total body fat amoun... 3 | 207
decreased vertical activity 3 | 208
enlarged heart 3 | 210
hypoactivity 3 | 132
abnormal heart morphology 2 | 162
abnormal sleep behavior 2 | 70
decreased circulating triglyce... 2 | 79
decreased leukocyte cell numbe... 2 | 73
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
improved glucose tolerance 2 | 79
increased circulating alkaline... 2 | 122
increased leukocyte cell numbe... 2 | 47
male infertility 2 | 123
microphthalmia 2 | 26
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal brain morphology 1 | 13
abnormal cecum morphology 1 | 7
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal eye morphology 1 | 68
abnormal neural tube morpholog... 1 | 12
abnormal pupil morphology 1 | 2
abnormal rib morphology 1 | 10
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
abnormal thymus morphology 1 | 7
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased cardiac output 1 | 3
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased prepulse inhibition 1 | 82
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged spleen 1 | 41
female infertility 1 | 60
hydroencephaly 1 | 14
impaired pupillary reflex 1 | 26
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
limb grasping 1 | 41
mammalian phenotype 1 | 17
pale yolk sac 1 | 25
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small testis 1 | 58
small thymus 1 | 16
thin ventricular wall 1 | 24

Disease

Carcinoma 52 | 11,493
psoriasis 47 | 6,694
ovarian cancer 39 | 8,520
lung cancer 36 | 4,740
Cancer 34 | 2,499
glioblastoma 34 | 5,792
medulloblastoma, large-cell 33 | 6,241
osteosarcoma 33 | 7,950
atypical teratoid / rhabdoid tumor 32 | 5,112
ependymoma 30 | 4,679
malignant mesothelioma 25 | 3,232
Schizophrenia 24 | 1,160
non-small cell lung cancer 23 | 2,890
Bipolar Disorder 22 | 666
Breast cancer 22 | 3,578
adult high grade glioma 21 | 3,801
diabetes mellitus 21 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,955
Obesity 20 | 678
oligodendroglioma 20 | 2,850
Depressive disorder 19 | 409
group 3 medulloblastoma 19 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
pituitary cancer 19 | 1,972
primitive neuroectodermal tumor 19 | 3,035
astrocytic glioma 18 | 2,597
Major Depressive Disorder 17 | 301
Mental Depression 17 | 333
colon cancer 17 | 1,478
invasive ductal carcinoma 17 | 2,951
lung adenocarcinoma 17 | 2,716
Astrocytoma, Pilocytic 16 | 3,081
breast carcinoma 16 | 1,638
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
lung carcinoma 16 | 2,843
Kidney cancer 15 | 2,613
subependymal giant cell astrocytoma 15 | 2,287
Pick disease 14 | 1,894
adrenocortical carcinoma 14 | 1,428
ductal carcinoma in situ 14 | 1,745
group 4 medulloblastoma 14 | 1,855
interstitial cystitis 14 | 2,312
Mood Disorders 13 | 184
pancreatic cancer 13 | 2,398
ulcerative colitis 13 | 1,819
Autosomal recessive predisposition 12 | 1,442
Rheumatoid arthritis 12 | 1,191
acute quadriplegic myopathy 12 | 1,158
Alzheimer's disease 11 | 658
Atopic dermatitis 11 | 952
Autistic Disorder 11 | 364
Breast Neoplasms 11 | 445
Diabetes Mellitus, Non-Insulin-Dependent 11 | 145
Diabetes Mellitus, Type 2 11 | 142
Mammary Neoplasms 11 | 425
Unipolar Depression 11 | 250
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
Diarrhea 10 | 253
Hypertension 10 | 396
tuberculosis 10 | 2,010
Alcoholic Intoxication, Chronic 9 | 289
Hyperglycemia 9 | 137
Parkinson's disease 9 | 392
astrocytoma 9 | 1,146
Atherosclerosis 8 | 291
Cerebrovascular disease 8 | 238
Diabetes Mellitus, Experimental 8 | 108
Liver Cirrhosis, Experimental 8 | 769
Liver disease 8 | 237
Waldenstrons macroglobulinemia 8 | 765
acute myeloid leukemia 8 | 783
aldosterone-producing adenoma 8 | 665
cutaneous lupus erythematosus 8 | 1,057
juvenile dermatomyositis 8 | 1,187
Down syndrome 7 | 499
Epilepsy 7 | 792
Fatty liver disease 7 | 103
Hypertensive disease 7 | 292
Lung Neoplasms 7 | 232
Polycystic ovary syndrome 7 | 360
Seasonal affective disorder 7 | 28
Stomach Neoplasms 7 | 300
Toxic encephalopathy 7 | 141
cystic fibrosis 7 | 1,696
hepatocellular carcinoma 7 | 547
spina bifida 7 | 1,074
Amyotrophic lateral sclerosis 6 | 451
Arthritis 6 | 290
Carcinoma, Hepatocellular 6 | 228
Colonic Neoplasms 6 | 142
Endometriosis 6 | 540
Heart disease 6 | 306
Lipid metabolism disorder 6 | 114
Liver carcinoma 6 | 240
Multiple myeloma 6 | 1,332
Prostatic Neoplasms 6 | 495
Seizures 6 | 596
active Crohn's disease 6 | 922
dermatomyositis 6 | 966
pediatric high grade glioma 6 | 1,064

Tissue

Endocrine System 74 | 18,159
Nervous System 72 | 16,725
Digestive Tract 71 | 17,369
Female tissues 71 | 17,400
Male tissues 71 | 17,142
Blood and immune system 69 | 16,909
Skin and soft tissues 69 | 17,230
Liver and Pancreas 68 | 16,750
Urinary Tract 68 | 16,678
Respiratory system 64 | 16,393
Cardiovascular System 62 | 15,192

Target Family

Transcription Factor 21 | 1,400
Non-IDG 20 | 12,091
Enzyme 15 | 4,145
Kinase 7 | 634
GPCR 5 | 408
Epigenetic 2 | 242
Transporter 2 | 473
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

GO Process

circadian rhythm 74 | 74
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cone-rod homeobox protein CRX Tbio Transcription Factor -2.44826 272.0 185
High affinity nerve growth factor receptor NTRK1 Tclin Kinase -3.05841 1050.9 1092
Dual specificity tyrosine-phosphorylation-regulated kinase 1A DYRK1A Tchem Kinase -2.68760 506.6 336
N6-adenosine-methyltransferase catalytic subunit METTL3 Tbio Enzyme -1.76174 60.5 94
Thyroid hormone receptor-associated protein 3 THRAP3 Tbio Non-IDG -0.87769 8.81 136
D site-binding protein DBP Tbio Transcription Factor -1.50821 28.6 93
Protein timeless homolog TIMELESS Tbio Non-IDG -2.76871 578.0 138
Thymidylate synthase TYMS Tclin Enzyme -2.93426 732.0 733
Krueppel-like factor 9 KLF9 Tbio Transcription Factor -1.95524 99.9 158
DNA topoisomerase 1 TOP1 Tclin Enzyme -3.61701 4015.4 248