Development Level

Tbio 31 | 11,651
Tchem 16 | 1,388
Tclin 7 | 612
Tdark 1 | 6,593

IMPC Phenotype

preweaning lethality, complete... 8 | 979
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
decreased total body fat amoun... 3 | 207
embryonic lethality prior to t... 3 | 278
abnormal bone mineralization 2 | 38
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
decreased bone mineral density 2 | 126
decreased circulating alkaline... 2 | 46
enlarged heart 2 | 210
increased bone mineral content 2 | 108
increased lean body mass 2 | 172
abnormal brain morphology 1 | 13
abnormal coat-hair pigmentatio... 1 | 64
abnormal digit morphology 1 | 10
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal lens morphology 1 | 81
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased body weight 1 | 161
decreased cardiac output 1 | 3
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased fasted circulating g... 1 | 65
decreased lean body mass 1 | 135
decreased lumbar vertebrae num... 1 | 2
decreased mean corpuscular vol... 1 | 79
decreased red blood cell distr... 1 | 41
decreased sacral vertebrae num... 1 | 1
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
hydroencephaly 1 | 14
hyperactivity 1 | 148
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased lumbar vertebrae num... 1 | 1
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased sacral vertebrae num... 1 | 1
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
limb grasping 1 | 41
mammalian phenotype 1 | 17
pale yolk sac 1 | 25
thin ventricular wall 1 | 24
thrombocytopenia 1 | 56
tremors 1 | 39

Disease

Carcinoma 44 | 11,493
ovarian cancer 36 | 8,520
psoriasis 35 | 6,694
osteosarcoma 34 | 7,950
medulloblastoma, large-cell 26 | 6,241
Cancer 25 | 2,499
Schizophrenia 23 | 1,160
glioblastoma 22 | 5,792
atypical teratoid / rhabdoid tumor 21 | 5,112
lung cancer 21 | 4,740
Bipolar Disorder 19 | 666
Breast cancer 19 | 3,578
group 3 medulloblastoma 18 | 4,104
primitive neuroectodermal tumor 18 | 3,035
Obesity 17 | 678
Depressive disorder 15 | 409
ependymoma 15 | 4,679
Mental Depression 14 | 333
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
malignant mesothelioma 14 | 3,232
non-small cell lung cancer 14 | 2,890
diabetes mellitus 13 | 1,728
invasive ductal carcinoma 13 | 2,951
adult high grade glioma 12 | 3,801
colon cancer 11 | 1,478
spina bifida 11 | 1,074
acute quadriplegic myopathy 10 | 1,158
astrocytoma 10 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
lung carcinoma 10 | 2,843
oligodendroglioma 10 | 2,850
subependymal giant cell astrocytoma 10 | 2,287
Kidney cancer 9 | 2,613
Seasonal affective disorder 9 | 28
adrenocortical carcinoma 9 | 1,428
astrocytic glioma 9 | 2,597
cystic fibrosis 9 | 1,696
group 4 medulloblastoma 9 | 1,855
interstitial cystitis 9 | 2,312
lung adenocarcinoma 9 | 2,716
Multiple myeloma 8 | 1,332
Pick disease 8 | 1,894
Prostatic Neoplasms 8 | 495
Waldenstrons macroglobulinemia 8 | 765
aldosterone-producing adenoma 8 | 665
breast carcinoma 8 | 1,638
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
pituitary cancer 8 | 1,972
tuberculosis 8 | 2,010
ulcerative colitis 8 | 1,819
Astrocytoma, Pilocytic 7 | 3,081
Mood Disorders 7 | 184
juvenile dermatomyositis 7 | 1,187
pancreatic cancer 7 | 2,398
Alcoholic Intoxication, Chronic 6 | 289
Alzheimer's disease 6 | 658
Amyotrophic lateral sclerosis 6 | 451
Leukemia, Myelogenous, Chronic, BCR-ABL Positive 6 | 20
Myeloid Leukemia, Chronic 6 | 23
Rheumatoid arthritis 6 | 1,191
cutaneous lupus erythematosus 6 | 1,057
ductal carcinoma in situ 6 | 1,745
pediatric high grade glioma 6 | 1,064
Atherosclerosis 5 | 291
Autistic Disorder 5 | 364
Breast Neoplasms 5 | 445
Cocaine Dependence 5 | 51
Endometriosis 5 | 540
Hyperglycemia 5 | 137
Intellectual disability 5 | 1,016
Liver Cirrhosis, Experimental 5 | 769
Mammary Neoplasms 5 | 425
gastric carcinoma 5 | 807
head and neck cancer 5 | 271
hepatocellular carcinoma 5 | 547
hereditary spastic paraplegia 5 | 318
primary pancreatic ductal adenocarcinoma 5 | 1,109
Atopic dermatitis 4 | 952
Chronic Lymphocytic Leukemia 4 | 262
Crohn's disease 4 | 321
Diabetes Mellitus, Non-Insulin-Dependent 4 | 145
Diabetes Mellitus, Type 2 4 | 142
Fatty Liver 4 | 70
Fatty liver disease 4 | 103
Huntington's disease 4 | 76
Hypertension 4 | 396
Insulin Resistance 4 | 72
Major Depressive Disorder 4 | 301
Parkinson's disease 4 | 392
Seizures 4 | 596
Substance Withdrawal Syndrome 4 | 55
Unipolar Depression 4 | 250
acute myeloid leukemia 4 | 783
dermatomyositis 4 | 966
gastric cancer 4 | 459
interstitial lung disease 4 | 298
posterior fossa group B ependymoma 4 | 416
Attention deficit hyperactivity disorder 3 | 278
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510

Tissue

Endocrine System 55 | 18,159
Digestive Tract 53 | 17,369
Female tissues 53 | 17,400
Liver and Pancreas 53 | 16,750
Male tissues 53 | 17,142
Nervous System 53 | 16,725
Skin and soft tissues 53 | 17,230
Respiratory system 52 | 16,393
Cardiovascular System 51 | 15,192
Urinary Tract 51 | 16,678
Blood and immune system 50 | 16,909

Target Family

Non-IDG 17 | 12,091
Transcription Factor 11 | 1,400
Enzyme 9 | 4,145
Epigenetic 6 | 242
GPCR 4 | 408
Nuclear Receptor 4 | 48
Kinase 2 | 634
TF/Epigenetic 2 | 38

GO Process

circadian regulation of gene e... 55 | 55
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nicotinamide phosphoribosyltransferase NAMPT Tchem Enzyme -2.94790 1054.3 667
Nocturnin NOCT Tbio Non-IDG -1.84562 69.3 92
Neuronal PAS domain-containing protein 2 NPAS2 Tbio Transcription Factor -1.91320 81.4 182
D(2) dopamine receptor DRD2 Tclin GPCR -3.28700 1882.2 264
Period circadian protein homolog 2 PER2 Tchem Non-IDG -2.67778 457.4 219
Nuclear receptor ROR-gamma RORC Tchem Nuclear Receptor -2.17159 123.2 478
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PPP1CA Tchem Enzyme -2.17010 139.0 378
Serine/threonine-protein phosphatase PP1-beta catalytic subunit PPP1CB Tbio Enzyme -1.55192 33.3 377
Leucine-rich repeat-containing G-protein coupled receptor 4 LGR4 Tbio GPCR -1.75604 72.2 230
Histone deacetylase 1 HDAC1 Tclin Epigenetic -3.03775 954.3 1201