Development Level

Tbio 138 | 11,445
Tdark 30 | 6,588
Tchem 6 | 1,598
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Comple... 2 | 37
Kinase: IDG Consortium (Target... 2 | 125
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, complete... 19 | 979
preweaning lethality, incomple... 10 | 499
embryonic lethality prior to t... 5 | 278
increased lean body mass 5 | 172
abnormal behavior 4 | 298
decreased bone mineral density 3 | 126
decreased circulating glucose ... 3 | 126
embryonic lethality prior to o... 3 | 239
increased circulating alkaline... 3 | 122
increased fasted circulating g... 3 | 76
male infertility 3 | 123
abnormal embryo size 2 | 220
abnormal humerus morphology 2 | 11
decreased bone mineral content 2 | 151
decreased circulating potassiu... 2 | 20
decreased grip strength 2 | 116
embryonic growth retardation 2 | 106
enlarged heart 2 | 210
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased body weight 2 | 25
increased bone mineral density 2 | 72
increased circulating chloride... 2 | 41
increased mean corpuscular hem... 2 | 96
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
prenatal lethality prior to he... 2 | 87
short tibia 2 | 97
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal embryo turning 1 | 31
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal pancreas morphology 1 | 13
abnormal pelvic girdle bone mo... 1 | 12
abnormal pericardium morpholog... 1 | 26
abnormal response to tactile s... 1 | 17
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
brachydactyly 1 | 19
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
convulsive seizures 1 | 13
decreased body length 1 | 101
decreased body weight 1 | 161
decreased caudal vertebrae num... 1 | 53
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating glycerol... 1 | 16
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased coping response 1 | 8
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased heart rate variabili... 1 | 13
decreased heart weight 1 | 27
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased mean platelet volume 1 | 25
decreased respiratory quotient 1 | 16
decreased spleen weight 1 | 10
decreased total body fat amoun... 1 | 207
edema 1 | 59
hydrometra 1 | 53
hyperactivity 1 | 148
increased anti-nuclear antigen... 1 | 19
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating amylase ... 1 | 25
increased circulating aspartat... 1 | 15
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased circulating glycerol... 1 | 9
increased circulating insulin ... 1 | 3
increased heart rate 1 | 23
increased heart rate variabili... 1 | 7
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased prepulse inhibition 1 | 32
long tibia 1 | 25
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
shortened RR interval 1 | 17
small superior vagus ganglion 1 | 74
small testis 1 | 58
syndactyly 1 | 23
thrombocytosis 1 | 27

Disease

Carcinoma 124 | 11,493
ovarian cancer 90 | 8,520
ependymoma 86 | 4,679
osteosarcoma 81 | 7,950
medulloblastoma, large-cell 59 | 6,241
glioblastoma 53 | 5,792
psoriasis 52 | 6,694
atypical teratoid / rhabdoid tumor 50 | 5,112
group 3 medulloblastoma 47 | 4,104
lung cancer 46 | 4,740
Breast cancer 43 | 3,578
Polydactyly 41 | 107
Ciliopathy 39 | 71
astrocytic glioma 36 | 2,597
chronic rhinosinusitis 35 | 512
primitive neuroectodermal tumor 34 | 3,035
Autosomal recessive predisposition 32 | 1,442
Nephronophthisis 32 | 80
Intellectual disability 30 | 1,016
Kidney cancer 30 | 2,613
adult high grade glioma 30 | 3,801
malignant mesothelioma 30 | 3,232
oligodendroglioma 30 | 2,850
intraductal papillary-mucinous adenoma (IPMA) 28 | 2,955
invasive ductal carcinoma 28 | 2,951
Joubert syndrome 27 | 66
lung carcinoma 27 | 2,843
Pick disease 26 | 1,894
Astrocytoma, Pilocytic 25 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,291
tuberculosis 24 | 2,010
Bardet-Biedl syndrome 23 | 51
Dull intelligence 23 | 645
Low intelligence 23 | 645
Mental Retardation 23 | 645
Mental deficiency 23 | 645
Obesity 23 | 678
Poor school performance 23 | 645
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
lung adenocarcinoma 23 | 2,716
Asphyxiating thoracic dystrophy 22 | 44
Nystagmus 22 | 317
Retinitis Pigmentosa 22 | 226
non-small cell lung cancer 22 | 2,890
Meckel syndrome 21 | 46
Short stature 21 | 531
nasopharyngeal carcinoma 21 | 1,058
Primary ciliary dyskinesia 20 | 76
pancreatic cancer 20 | 2,398
Cognitive delay 18 | 608
Global developmental delay 18 | 608
Hydrocephalus 18 | 152
Mental and motor retardation 18 | 608
subependymal giant cell astrocytoma 18 | 2,287
group 4 medulloblastoma 17 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,962
colon cancer 16 | 1,478
progressive supranuclear palsy 16 | 676
Bardet-Biedl syndrome 1 15 | 22
Congenital hypoplasia of penis 15 | 176
Orofaciodigital syndrome 15 | 21
Ulnar polydactyly of fingers 15 | 47
interstitial cystitis 15 | 2,312
posterior fossa group B ependymoma 15 | 416
Brachydactyly 14 | 156
Electroretinogram abnormal 14 | 95
Hypertensive disease 14 | 292
Increase in blood pressure 14 | 119
Senior-Loken syndrome 14 | 22
Situs Inversus 14 | 65
breast carcinoma 14 | 1,638
cystic fibrosis and chronic rhinosinusitis 14 | 214
ductal carcinoma in situ 14 | 1,745
pediatric high grade glioma 14 | 1,064
pituitary cancer 14 | 1,972
Cerebellar Ataxia 13 | 304
Familial aplasia of the vermis 13 | 19
adrenocortical carcinoma 13 | 1,428
Cataract 12 | 297
Fundus dystrophy 12 | 83
Hypogonadism 12 | 173
Lens Opacities 12 | 231
Multicystic Dysplastic Kidney 12 | 52
Optic Atrophy 12 | 242
Retinal Degeneration 12 | 106
Sensenbrenner syndrome 12 | 17
active Crohn's disease 12 | 922
diabetes mellitus 12 | 1,728
ulcerative colitis 12 | 1,819
Cone dystrophy 11 | 71
Cryptorchidism 11 | 296
Hypoplastic mandible condyle 11 | 275
Low set ears 11 | 181
Mandibular hypoplasia 11 | 275
Micrognathism 11 | 275
Rheumatoid arthritis 11 | 1,191
acute quadriplegic myopathy 11 | 1,158
Cleft Palate 10 | 271
Meckel-Gruber syndrome 10 | 13
Uranostaphyloschisis 10 | 167

Tissue

Endocrine System 173 | 18,159
Digestive Tract 170 | 17,369
Female tissues 170 | 17,400
Liver and Pancreas 170 | 16,750
Skin and soft tissues 170 | 17,230
Nervous System 169 | 16,725
Male tissues 168 | 17,142
Respiratory system 168 | 16,393
Urinary Tract 168 | 16,678
Blood and immune system 166 | 16,909
Cardiovascular System 153 | 15,192

Target Family

Non-IDG 139 | 12,091
Enzyme 20 | 4,145
Kinase 6 | 634
Transcription Factor 6 | 1,400
Epigenetic 2 | 242
GPCR 1 | 408
Transporter 1 | 473

GO Process

cilium assembly 175 | 175
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
B9 domain-containing protein 1 B9D1 Tdark Non-IDG -0.61316 3.72 43
Centrosomal protein of 41 kDa CEP41 Tdark Non-IDG -0.41185 3.40 46
Bardet-Biedl syndrome 2 protein BBS2 Tbio Non-IDG -2.84516 693.9 69
Fibrocystin PKHD1 Tbio Non-IDG -1.71770 56.1 82
Kinesin-like protein KIF27 KIF27 Tbio Non-IDG -0.76788 4.95 63
Doublecortin domain-containing protein 2 DCDC2 Tbio Non-IDG -1.71331 52.4 209
Sodium channel and clathrin linker 1 SCLT1 Tdark Non-IDG -0.50820 2.61 97
Intraflagellar transport protein 52 homolog IFT52 Tbio Non-IDG -1.09507 12.7 13
Rab-3A-interacting protein RAB3IP Tbio Non-IDG -1.03500 11.6 89
WD repeat-containing protein 60 WDR60 Tbio Non-IDG -0.64761 3.98 23