Development Level

Tbio 50 | 11,445
Tchem 9 | 1,598
Tclin 3 | 613
Tdark 2 | 6,588

Collection

Kinase: IDG Consortium (Target... 3 | 125

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
cataract 2 | 92
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
thrombocytopenia 2 | 56
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal head morphology 1 | 10
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal retinal inner nuclear... 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal tail morphology 1 | 25
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating choleste... 1 | 93
decreased erythrocyte cell num... 1 | 62
decreased heart left ventricle... 1 | 28
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged lymph nodes 1 | 37
hemorrhage 1 | 23
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased circulating HDL chol... 1 | 80
increased circulating thyroxin... 1 | 7
increased fasted circulating g... 1 | 76
increased leukocyte cell numbe... 1 | 47
preweaning lethality, incomple... 1 | 499
thrombocytosis 1 | 27

Disease

ovarian cancer 43 | 8,520
Carcinoma 41 | 11,493
medulloblastoma, large-cell 41 | 6,241
psoriasis 34 | 6,694
glioblastoma 30 | 5,792
group 3 medulloblastoma 29 | 4,104
atypical teratoid / rhabdoid tumor 26 | 5,112
primitive neuroectodermal tumor 26 | 3,035
Breast cancer 25 | 3,578
non-small cell lung cancer 25 | 2,890
osteosarcoma 25 | 7,950
lung cancer 24 | 4,740
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,291
lung adenocarcinoma 22 | 2,716
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,989
adrenocortical carcinoma 19 | 1,428
adult high grade glioma 19 | 3,801
Cancer 18 | 2,499
invasive ductal carcinoma 18 | 2,951
Endometriosis 16 | 540
Atopic dermatitis 15 | 952
breast carcinoma 15 | 1,638
ductal carcinoma in situ 15 | 1,745
colon cancer 14 | 1,478
malignant mesothelioma 14 | 3,232
ependymoma 13 | 4,679
nasopharyngeal carcinoma 12 | 1,058
oligodendroglioma 12 | 2,850
pancreatic cancer 11 | 2,398
Astrocytoma, Pilocytic 9 | 3,081
Intellectual disability 9 | 1,016
ulcerative colitis 9 | 1,819
Multiple myeloma 8 | 1,332
group 4 medulloblastoma 8 | 1,855
Dull intelligence 7 | 645
Kidney cancer 7 | 2,613
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Poor school performance 7 | 645
astrocytic glioma 7 | 2,597
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
pediatric high grade glioma 7 | 1,064
Schizophrenia 6 | 1,160
Small head 6 | 374
Waldenstrons macroglobulinemia 6 | 765
dermatomyositis 6 | 966
tuberculosis 6 | 2,010
Autosomal recessive predisposition 5 | 1,442
Cognitive delay 5 | 608
Global developmental delay 5 | 608
Mental and motor retardation 5 | 608
Muscle hypotonia 5 | 571
Short stature 5 | 531
astrocytoma 5 | 1,146
interstitial cystitis 5 | 2,312
non primary Sjogren syndrome sicca 5 | 891
primary Sjogren syndrome 5 | 735
Epilepsy 4 | 792
Microcephaly 4 | 166
Pick disease 4 | 1,894
Prostatic Neoplasms 4 | 495
Rheumatoid arthritis 4 | 1,191
Seizures 4 | 596
Systemic lupus erythematosus 4 | 194
acute quadriplegic myopathy 4 | 1,158
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
pituitary cancer 4 | 1,972
posterior fossa group A ependymoma 4 | 468
subependymal giant cell astrocytoma 4 | 2,287
Anteverted nostril 3 | 191
Asthma 3 | 385
Breast Neoplasms 3 | 445
Broad flat nasal bridge 3 | 236
Cerebellar Hypoplasia 3 | 61
Crohn's disease 3 | 321
Downward slant of palpebral fissure 3 | 158
Endometrial cancer 3 | 311
Gaucher disease type 1 3 | 180
Hydrocephalus 3 | 152
Hypoplastic mandible condyle 3 | 275
Liver Cirrhosis, Experimental 3 | 769
Mammary Neoplasms 3 | 425
Mandibular hypoplasia 3 | 275
Melanoma 3 | 711
Mental Depression 3 | 333
Micrognathism 3 | 275
Multiple Sclerosis 3 | 540
Nasal bridge wide 3 | 236
Psychotic Disorders 3 | 151
Sloping forehead 3 | 46
Xeroderma pigmentosum group D 3 | 33
acute myeloid leukemia 3 | 783
atypical teratoid/rhabdoid tumor 3 | 357
esophageal adenocarcinoma 3 | 737
gastric cancer 3 | 459
interstitial lung disease 3 | 298
juvenile dermatomyositis 3 | 1,187
lung carcinoma 3 | 2,843
tuberculosis and treatment for 6 months 3 | 409

Tissue

Blood and immune system 64 | 16,909
Digestive Tract 64 | 17,369
Endocrine System 64 | 18,159
Female tissues 64 | 17,400
Liver and Pancreas 64 | 16,750
Male tissues 64 | 17,142
Nervous System 64 | 16,725
Respiratory system 64 | 16,393
Skin and soft tissues 64 | 17,230
Urinary Tract 64 | 16,678
Cardiovascular System 61 | 15,192

Target Family

Non-IDG 40 | 12,091
Enzyme 14 | 4,145
Kinase 5 | 634
Epigenetic 1 | 242
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38
Transcription Factor 1 | 1,400
Transporter 1 | 473

GO Process

chromosome segregation 64 | 64
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA topoisomerase 3-beta-1 TOP3B Tbio Enzyme -1.06981 9.54 153
Nuclear distribution protein nudE homolog 1 NDE1 Tbio Non-IDG -2.01711 96.0 192
Sperm-associated antigen 5 SPAG5 Tbio Non-IDG -1.72743 51.4 136
Nuclear mitotic apparatus protein 1 NUMA1 Tbio Non-IDG -2.76544 575.8 235
Small kinetochore-associated protein KNSTRN Tbio Non-IDG -1.28291 21.4 32
ADP-ribosylation factor-like protein 8B ARL8B Tbio Enzyme -0.99083 12.0 99
Spindle and kinetochore-associated protein 2 SKA2 Tbio Non-IDG -1.23206 10.2 108
Probable cytosolic iron-sulfur protein assembly protein CIAO1 CIAO1 Tbio Non-IDG -1.44311 25.1 161
Kinesin-like protein KIF11 KIF11 Tchem Non-IDG -2.61375 404.4 300
Regulator of G-protein signaling 14 RGS14 Tbio Non-IDG -1.61170 43.9 233