Development Level

Tbio 4 | 11,445
Tchem 3 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal bone mineralization 1 | 38
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal startle reflex 1 | 15
decreased NK T cell number 1 | 2
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased coping response 1 | 8
decreased lean body mass 1 | 135
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
female infertility 1 | 60
hypoactivity 1 | 132
increased bone mineral density 1 | 72
increased circulating sodium l... 1 | 71
increased mean corpuscular hem... 1 | 96
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
preweaning lethality, incomple... 1 | 499

Disease

Breast cancer 6 | 3,578
atypical teratoid / rhabdoid tumor 6 | 5,112
glioblastoma 6 | 5,792
medulloblastoma, large-cell 6 | 6,241
osteosarcoma 6 | 7,950
ovarian cancer 6 | 8,520
primitive neuroectodermal tumor 6 | 3,035
psoriasis 6 | 6,694
Carcinoma 5 | 11,493
ependymoma 5 | 4,679
lung cancer 5 | 4,740
Cancer 4 | 2,499
Carcinoma, Hepatocellular 4 | 228
Endometrial cancer 4 | 311
Intellectual disability 4 | 1,016
Liver carcinoma 4 | 240
group 3 medulloblastoma 4 | 4,104
malignant mesothelioma 4 | 3,232
pancreatic cancer 4 | 2,398
Kidney cancer 3 | 2,613
Liver cancer 3 | 604
Schizophrenia 3 | 1,160
adult high grade glioma 3 | 3,801
invasive ductal carcinoma 3 | 2,951
tuberculosis 3 | 2,010
Adenocarcinoma 2 | 122
Alzheimer's disease 2 | 658
Astrocytoma, Pilocytic 2 | 3,081
Breast Neoplasms 2 | 445
Coffin-Siris syndrome 2 | 17
Cognitive delay 2 | 608
Colorectal Neoplasms 2 | 243
Dull intelligence 2 | 645
Endometriosis 2 | 540
Global developmental delay 2 | 608
Immune system cancer 2 | 140
Large intestine cancer 2 | 126
Low intelligence 2 | 645
Lymphoid leukemia 2 | 160
Mammary Neoplasms 2 | 425
Melanoma 2 | 711
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Muscle hypotonia 2 | 571
Neuroblastoma 2 | 80
Neurodevelopmental Disorders 2 | 70
Poor school performance 2 | 645
Skin cancer 2 | 469
Small head 2 | 374
Stomach Neoplasms 2 | 300
Stomach cancer 2 | 30
Strabismus 2 | 270
Wilms Tumor 2 | 28
adrenocortical carcinoma 2 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
colon cancer 2 | 1,478
ductal carcinoma in situ 2 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
medulloblastoma 2 | 720
nasopharyngeal carcinoma 2 | 1,058
non-small cell lung cancer 2 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
subependymal giant cell astrocytoma 2 | 2,287
Adrenal Gland Neoplasms 1 | 11
Adrenal gland cancer 1 | 12
Ameloblastoma 1 | 24
Angiosarcoma 1 | 11
Biliary tract cancer 1 | 19
Bone cancer 1 | 16
Bushy eyebrows 1 | 49
Cerebral calcification 1 | 43
Colorectal cancer 1 | 25
DOID:3858 1 | 6
DOID:8600 1 | 4
DOID:9917 1 | 31
Full lower lip 1 | 64
Hemangiosarcoma 1 | 18
Hepatoblastoma 1 | 19
Hypertrichosis 1 | 46
Increased hepatocellular carcinoma risk 1 | 27
Increased incidence of hepatocellular carcinoma 1 | 27
Intestinal Neoplasms 1 | 12
Intestinal benign neoplasm 1 | 12
Liver Neoplasms, Experimental 1 | 59
Micronodular cirrhosis 1 | 12
Papilledema 1 | 11
Pilomatrixoma 1 | 12
Polyploidy 1 | 4
Prominent lower lip 1 | 64
Retroperitoneal cancer 1 | 4
Sertoli cell-only syndrome 1 | 37
Short distal phalanges 1 | 50
T-Cell Lymphoma 1 | 13
Thyroid cancer 1 | 36
Uterine adnexa cancer 1 | 4

Tissue

Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Non-IDG 4 | 12,091
Transcription Factor 2 | 1,400
Enzyme 1 | 4,145
Epigenetic 1 | 242
Kinase 1 | 634

GO Process

chromatin-mediated maintenance... 9 | 9
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone-lysine N-methyltransferase 2B KMT2B Tbio Epigenetic -1.93899 84.8 153
Polyadenylate-binding protein 1-like PABPC1L Tdark Non-IDG -1.22792 17.3 32
Transcription elongation factor 1 homolog ELOF1 Tdark Non-IDG -0.30103 2.00 59
AT-rich interactive domain-containing protein 1B ARID1B Tbio Transcription Factor -1.88304 66.9 120
AT-rich interactive domain-containing protein 1A ARID1A Tbio Transcription Factor -2.61778 423.3 132
Serine/threonine-protein kinase Chk1 CHEK1 Tchem Kinase -3.04423 1089.6 1375
Protein-arginine deiminase type-2 PADI2 Tchem Enzyme -2.21849 164.2 156
Catenin beta-1 CTNNB1 Tchem Non-IDG -3.99948 9786.0 3058
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 SMARCD1 Tbio Non-IDG -1.28639 17.5 184