Development Level

Tbio 20 | 10,625
Tdark 12 | 7,003
Tchem 4 | 1,890
Tclin 1 | 602

IMPC Term

decreased rib number 2 | 59
preweaning lethality, incomple... 2 | 260
abnormal gait 1 | 51
abnormal iris morphology 1 | 12
abnormal maxilla morphology 1 | 16
abnormal placement of pupils 1 | 4
abnormal snout morphology 1 | 18
abnormal tooth morphology 1 | 24
hyperactivity 1 | 108
increased bone mineral density 1 | 52
increased circulating choleste... 1 | 53
increased circulating fructosa... 1 | 11
increased circulating total pr... 1 | 20
increased grip strength 1 | 83
increased or absent threshold ... 1 | 128
irregularly shaped pupil 1 | 7
narrow eye opening 1 | 15
oligodactyly 1 | 14

Disease

osteosarcoma 13 | 7,933
psoriasis 13 | 6,685
ovarian cancer 12 | 8,484
Breast cancer 11 | 3,094
lung cancer 10 | 4,466
Cancer 9 | 2,346
lung adenocarcinoma 8 | 2,713
medulloblastoma, large-cell 8 | 6,234
glioblastoma 7 | 5,572
invasive ductal carcinoma 7 | 2,950
malignant mesothelioma 7 | 3,162
breast carcinoma 6 | 1,614
diabetes mellitus 6 | 1,663
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,289
Multiple myeloma 5 | 1,327
atypical teratoid / rhabdoid tumor 5 | 4,369
ductal carcinoma in situ 5 | 1,745
group 4 medulloblastoma 5 | 1,875
non-small cell lung carcinoma 5 | 413
subependymal giant cell astrocytoma 5 | 2,287
adrenocortical carcinoma 4 | 1,427
ependymoma 4 | 2,514
non-small cell lung cancer 4 | 2,798
primitive neuroectodermal tumor 4 | 3,031
Carcinoma 3 | 2,147
Male infertility 3 | 170
Mammary Neoplasms 3 | 410
Metabolic syndrome X 3 | 155
Obesity 3 | 616
Rheumatoid Arthritis 3 | 1,160
Waldenstrons macroglobulinemia 3 | 765
astrocytic glioma 3 | 2,241
cutaneous lupus erythematosus 3 | 1,056
gastric cancer 3 | 430
group 3 medulloblastoma 3 | 2,254
hepatocellular carcinoma 3 | 532
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
non primary Sjogren syndrome sicca 3 | 840
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
pediatric high grade glioma 3 | 2,712
pituitary cancer 3 | 1,972
Cleft palate 2 | 125
Cocaine-Related Disorders 2 | 88
Connective tissue disease 2 | 59
Endometriosis 2 | 535
Huntington's disease 2 | 72
IGA Glomerulonephritis 2 | 454
Intellectual disability 2 | 573
Leishmaniasis 2 | 49
Lupus erythematosus 2 | 80
Parkinson's disease 2 | 364
Pick disease 2 | 1,893
Thyroiditis 2 | 25
acute myeloid leukemia 2 | 780
adult high grade glioma 2 | 2,148
atypical teratoid/rhabdoid tumor 2 | 1,095
colon cancer 2 | 1,475
medulloblastoma 2 | 1,524
oligodendroglioma 2 | 2,849
pancreatic cancer 2 | 2,300
pancreatic carcinoma 2 | 567
pilocytic astrocytoma 2 | 3,086
primary pancreatic ductal adenocarcinoma 2 | 1,271
sonic hedgehog group medulloblastoma 2 | 1,482
Acute kidney injury 1 | 65
Angelman syndrome 1 | 38
Autoimmune Diseases 1 | 33
Bruxism 1 | 19
Child Development Disorders, Pervasive 1 | 55
Chronic Lymphocytic Leukemia 1 | 242
Colitis 1 | 46
Craniofacial Abnormalities 1 | 147
Creutzfeldt-Jakob disease 1 | 19
Developmental Disabilities 1 | 20
Diabetes Mellitus, Experimental 1 | 106
Fanconi's anemia 1 | 50
Fatty Liver 1 | 48
Fatty liver disease 1 | 84
Fibrosis 1 | 40
Fragile X syndrome 1 | 31
HIV Infections 1 | 100
Immune system cancer 1 | 38
Kabuki syndrome 1 | 27
Kidney cancer 1 | 118
Learning disability 1 | 20
Lymphoma, Follicular 1 | 20
Microcephaly 1 | 149
Neoplasm Recurrence, Local 1 | 23
Nijmegen breakage syndrome 1 | 23
Non-alcoholic Fatty Liver Disease 1 | 40
Osteoporosis 1 | 257
PITT-HOPKINS SYNDROME 1 | 21
Paralysed 1 | 9
Pneumonia 1 | 133
Primary ciliary dyskinesia 1 | 73
Progressive relapsing multiple sclerosis 1 | 18
Seckel syndrome 1 | 34
Squamous cell carcinoma of esophagus 1 | 82
non-inflammatory breast cancer 1 | 208

Tissue

Female tissues 34 | 18,647
Liver and Pancreas 33 | 18,136
Male tissues 33 | 17,969
Nervous System 33 | 18,561
Endocrine System 32 | 18,512
Urinary Tract 32 | 18,444
Blood and immune system 31 | 17,995
Cardiovascular System 31 | 17,958
Digestive Tract 31 | 18,473
Respiratory system 31 | 17,484
Skin and soft tissues 25 | 18,115

Target Family

Non-IDG 27 | 11,971
Epigenetic 8 | 242
Enzyme 1 | 4,146
Transcription Factor 1 | 1,400

GO Process

chromatin silencing 37 | 37
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone deacetylase 5 HDAC5 Tclin Epigenetic -2.11372 127.6 466
Methyl-CpG-binding protein 2 MECP2 Tchem Transcription Factor -3.22710 1827.6 567
Spermatid-specific linker histone H1-like protein HILS1 Tbio Non-IDG 0.00000 0
Trinucleotide repeat-containing gene 18 protein TNRC18 Tdark Non-IDG 0.00000 17
E3 ubiquitin-protein ligase UBR2 UBR2 Tbio Enzyme -1.24581 19.4 144
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial SIRT4 Tchem Epigenetic -2.02454 115.1 229
Histone H2A type 2-B HIST2H2AB Tdark Non-IDG -0.51977 3.28 43
Histone H2A.V H2AFV Tdark Non-IDG -1.20240 14.0 30
Histone H2A type 1-J HIST1H2AJ Tdark Non-IDG -0.12825 1.19 10
Histone H2A.J H2AFJ Tdark Non-IDG 0.28 0.61 90