Development Level

Tbio 60 | 11,445
Tchem 12 | 1,598
Tdark 9 | 6,588
Tclin 6 | 613

IMPC Phenotype

preweaning lethality, complete... 13 | 979
preweaning lethality, incomple... 7 | 499
abnormal embryo size 5 | 220
embryonic lethality prior to t... 5 | 278
decreased body weight 4 | 161
embryonic lethality prior to o... 4 | 239
abnormal behavior 3 | 298
hypoactivity 3 | 132
increased bone mineral density 3 | 72
abnormal seminal vesicle morph... 2 | 114
decreased body length 2 | 101
decreased circulating HDL chol... 2 | 68
decreased circulating aspartat... 2 | 34
decreased circulating choleste... 2 | 93
decreased circulating total pr... 2 | 49
decreased erythrocyte cell num... 2 | 62
decreased vertical activity 2 | 208
hyperactivity 2 | 148
increased body length 2 | 32
increased body weight 2 | 25
increased circulating alkaline... 2 | 122
increased circulating phosphat... 2 | 26
increased hemoglobin content 2 | 45
increased mean corpuscular vol... 2 | 92
increased mean platelet volume 2 | 45
male infertility 2 | 123
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal lens morphology 1 | 81
abnormal maxilla morphology 1 | 17
abnormal pelvic girdle bone mo... 1 | 12
abnormal placenta size 1 | 20
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal rib morphology 1 | 10
abnormal stomach morphology 1 | 10
abnormal tail morphology 1 | 25
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 18
abnormal vertebral arch morpho... 1 | 9
abnormal vitreous body morphol... 1 | 10
abnormal vocalization 1 | 21
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased caudal vertebrae num... 1 | 53
decreased circulating alanine ... 1 | 47
decreased circulating bilirubi... 1 | 19
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased fluid intake 1 | 3
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lumbar vertebrae num... 1 | 2
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
long tibia 1 | 25
narrow eye opening 1 | 12
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
shortened QT interval 1 | 4
small superior vagus ganglion 1 | 74
thrombocytosis 1 | 27
vertebral fusion 1 | 23

Disease

Carcinoma 61 | 11,493
ovarian cancer 54 | 8,520
osteosarcoma 49 | 7,950
lung cancer 42 | 4,740
medulloblastoma, large-cell 40 | 6,241
psoriasis 38 | 6,694
glioblastoma 37 | 5,792
atypical teratoid / rhabdoid tumor 34 | 5,112
group 3 medulloblastoma 34 | 4,104
Cancer 32 | 2,499
primitive neuroectodermal tumor 29 | 3,035
Breast cancer 27 | 3,578
ependymoma 24 | 4,679
Kidney cancer 22 | 2,613
malignant mesothelioma 20 | 3,232
Rheumatoid arthritis 18 | 1,191
Intellectual disability 17 | 1,016
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
oligodendroglioma 15 | 2,850
pediatric high grade glioma 14 | 1,064
Multiple myeloma 13 | 1,332
Muscle hypotonia 13 | 571
astrocytic glioma 13 | 2,597
lung adenocarcinoma 13 | 2,716
Dull intelligence 12 | 645
Low intelligence 12 | 645
Mental Retardation 12 | 645
Mental deficiency 12 | 645
Poor school performance 12 | 645
Short stature 12 | 531
Small head 12 | 374
adult high grade glioma 12 | 3,801
astrocytoma 12 | 1,146
Astrocytoma, Pilocytic 11 | 3,081
acute myeloid leukemia 11 | 783
invasive ductal carcinoma 11 | 2,951
Broad flat nasal bridge 10 | 236
Concave bridge of nose 10 | 195
Cryptorchidism 10 | 296
Depressed nasal bridge 10 | 195
Depressed nasal root/bridge 10 | 195
Epilepsy 10 | 792
Nasal bridge wide 10 | 236
Pick disease 10 | 1,894
Seizures 10 | 596
Waldenstrons macroglobulinemia 10 | 765
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
pituitary cancer 10 | 1,972
Cognitive delay 9 | 608
Global developmental delay 9 | 608
Mental and motor retardation 9 | 608
colon cancer 9 | 1,478
diabetes mellitus 9 | 1,728
subependymal giant cell astrocytoma 9 | 2,287
tuberculosis 9 | 2,010
Adenoid Cystic Carcinoma 8 | 99
Carcinoma, Adenoid Cystic 8 | 99
Cleft Palate 8 | 271
Congenital deafness 8 | 185
Deafness 8 | 198
Hearing Loss, Partial 8 | 185
Schizophrenia 8 | 1,160
Strabismus 8 | 270
acute quadriplegic myopathy 8 | 1,158
dermatomyositis 8 | 966
ductal carcinoma in situ 8 | 1,745
group 4 medulloblastoma 8 | 1,855
hearing impairment 8 | 199
spina bifida 8 | 1,074
Bladder Neoplasm 7 | 112
Depressed nasal ridge 7 | 51
Full lower lip 7 | 64
Lung Neoplasms 7 | 232
Macrostomia 7 | 72
Prominent lower lip 7 | 64
Urinary Bladder Neoplasms 7 | 114
juvenile dermatomyositis 7 | 1,187
medulloblastoma 7 | 720
non-small cell lung cancer 7 | 2,890
pancreatic cancer 7 | 2,398
Abnormality of cardiovascular system morphology 6 | 23
Acquired scoliosis 6 | 281
Coarse facial features 6 | 108
Curvature of spine 6 | 282
Feeding difficulties in infancy 6 | 175
Fetal Growth Retardation 6 | 189
Hypoplastic mandible condyle 6 | 275
Infant, Small for Gestational Age 6 | 176
Intrauterine retardation 6 | 176
Joint hyperflexibility 6 | 78
Mandibular hypoplasia 6 | 275
Micrognathism 6 | 275
Uranostaphyloschisis 6 | 167
adrenocortical carcinoma 6 | 1,428
atypical teratoid/rhabdoid tumor 6 | 357
breast carcinoma 6 | 1,638
interstitial cystitis 6 | 2,312
lung carcinoma 6 | 2,843

Tissue

Digestive Tract 84 | 17,369
Endocrine System 84 | 18,159
Skin and soft tissues 84 | 17,230
Female tissues 82 | 17,400
Liver and Pancreas 82 | 16,750
Male tissues 82 | 17,142
Nervous System 82 | 16,725
Blood and immune system 81 | 16,909
Respiratory system 80 | 16,393
Urinary Tract 80 | 16,678
Cardiovascular System 78 | 15,192

Target Family

Non-IDG 31 | 12,091
Epigenetic 26 | 242
Transcription Factor 18 | 1,400
Enzyme 7 | 4,145
TF/Epigenetic 4 | 38
Nuclear Receptor 1 | 48

GO Process

chromatin remodeling 87 | 87
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tyrosine-protein kinase BAZ1B BAZ1B Tbio Epigenetic -1.45627 32.0 155
Bromodomain adjacent to zinc finger domain protein 2A BAZ2A Tchem TF/Epigenetic -2.07564 115.2 51
Transcription elongation factor SPT6 SUPT6H Tbio Non-IDG -1.80696 66.9 123
Probable global transcription activator SNF2L1 SMARCA1 Tbio Non-IDG -2.20560 145.6 116
Zinc finger and BTB domain-containing protein 1 ZBTB1 Tbio Transcription Factor -0.66768 5.75 59
Protein polybromo-1 PBRM1 Tchem TF/Epigenetic -1.92500 84.6 97
Lysine-specific demethylase 6B KDM6B Tchem Epigenetic -2.22888 174.2 272
Nucleosome-remodeling factor subunit BPTF BPTF Tchem Epigenetic -1.77472 58.0 68
Remodeling and spacing factor 1 RSF1 Tbio Epigenetic -1.69337 53.8 76
Protein-arginine deiminase type-4 PADI4 Tchem Enzyme -2.48712 319.5 342