Development Level

Tbio 21 | 10,625
Tchem 10 | 1,890
Tclin 6 | 602
Tdark 2 | 7,003

IMPC Phenotype

preweaning lethality, incomple... 4 | 260
corneal opacity 2 | 25
abnormal behavior 1 | 226
abnormal bone structure 1 | 131
abnormal iris morphology 1 | 12
abnormal maxilla morphology 1 | 16
abnormal placement of pupils 1 | 4
abnormal snout morphology 1 | 18
abnormal tooth morphology 1 | 24
abnormal vitreous body morphol... 1 | 7
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating serum al... 1 | 79
decreased rib number 1 | 59
decreased total body fat amoun... 1 | 186
hyperactivity 1 | 108
hypoactivity 1 | 89
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating alkaline... 1 | 119
increased circulating triglyce... 1 | 24
increased grip strength 1 | 83
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased mean platelet volume 1 | 19
increased neutrophil cell numb... 1 | 15
increased or absent threshold ... 1 | 128
increased sacral vertebrae num... 1 | 62
irregularly shaped pupil 1 | 7
narrow eye opening 1 | 15
oligodactyly 1 | 14
preweaning lethality, complete... 1 | 633

Disease

medulloblastoma, large-cell 18 | 6,234
osteosarcoma 18 | 7,933
glioblastoma 13 | 5,572
ovarian cancer 13 | 8,491
lung cancer 12 | 4,473
malignant mesothelioma 12 | 3,163
primitive neuroectodermal tumor 12 | 3,031
Cancer 11 | 2,346
atypical teratoid / rhabdoid tumor 11 | 4,369
ependymoma 10 | 2,514
pediatric high grade glioma 10 | 2,712
group 4 medulloblastoma 9 | 1,875
Breast cancer 8 | 3,098
Multiple myeloma 8 | 1,327
oligodendroglioma 8 | 2,849
psoriasis 8 | 6,685
atypical teratoid/rhabdoid tumor 7 | 1,095
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
pilocytic astrocytoma 7 | 3,086
subependymal giant cell astrocytoma 7 | 2,287
Peripheral T-cell lymphoma 6 | 24
Primary cutaneous T-cell lymphoma 6 | 29
adult high grade glioma 6 | 2,148
astrocytoma 6 | 1,493
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
posterior fossa group A ependymoma 6 | 1,511
interstitial cystitis 5 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,956
invasive ductal carcinoma 5 | 2,950
pancreatic cancer 5 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
Intellectual disability 4 | 573
Obesity 4 | 616
Rheumatoid Arthritis 4 | 1,170
Waldenstrons macroglobulinemia 4 | 764
adrenocortical carcinoma 4 | 1,427
breast carcinoma 4 | 1,614
cystic fibrosis 4 | 1,670
group 3 medulloblastoma 4 | 2,254
lung adenocarcinoma 4 | 2,714
medulloblastoma 4 | 1,524
non-small cell lung cancer 4 | 2,798
pituitary cancer 4 | 1,972
Diabetes Mellitus, Non-Insulin-Dependent 3 | 161
Heart Diseases 3 | 42
Polycystic Ovary Syndrome 3 | 334
Type 2 diabetes mellitus 3 | 192
astrocytic glioma 3 | 2,241
juvenile dermatomyositis 3 | 1,189
lung carcinoma 3 | 2,844
primary Sjogren syndrome 3 | 788
sonic hedgehog group medulloblastoma 3 | 1,482
tuberculosis 3 | 1,563
ulcerative colitis 3 | 2,087
Alzheimer's disease 2 | 644
Carcinoma 2 | 2,147
Chronic obstructive pulmonary disease 2 | 147
Coloboma 2 | 52
Endometriosis 2 | 535
Familial primary pulmonary hypertension 2 | 3
IGA Glomerulonephritis 2 | 454
Mammary Neoplasms 2 | 410
Parkinson's disease 2 | 364
Pick disease 2 | 1,893
Prostatic Neoplasms 2 | 471
Squamous cell carcinoma 2 | 96
Wilson-Turner X-Linked Mental Retardation Syndrome 2 | 2
active Crohn's disease 2 | 918
dermatomyositis 2 | 966
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
nasopharyngeal carcinoma 2 | 1,056
pancreatic carcinoma 2 | 567
primary pancreatic ductal adenocarcinoma 2 | 1,271
Amnestic disorder 1 | 37
Chondroma 1 | 12
Congenital dyserythropoietic anemia 1 | 17
Congenital heart disease 1 | 63
Cowpox 1 | 15
Diabetes Mellitus, Experimental 1 | 106
Diabetic Retinopathy 1 | 53
Epidermolytic hyperkeratosis 1 | 13
Esophageal atresia 1 | 25
Fatty Liver 1 | 48
Fatty liver disease 1 | 86
Fibrosis 1 | 40
Guillain-Barre syndrome 1 | 15
Hodgkin's lymphoma 1 | 11
Infant length 1 | 11
Juvenile Myelomonocytic Leukemia 1 | 21
Lambert-Eaton myasthenic syndrome 1 | 14
Lipoma 1 | 19
MYELODYSPLASTIC SYNDROME 1 | 39
Non-alcoholic Fatty Liver Disease 1 | 40
Paralysed 1 | 9
Sarcoma 1 | 49
Sertoli cell-only syndrome 1 | 36
Streptococcal pneumonia 1 | 6
Thyroid Neoplasm 1 | 33
Typhoid fever 1 | 22

Tissue

Blood and immune system 39 | 17,994
Endocrine System 39 | 18,511
Female tissues 39 | 18,646
Nervous System 39 | 18,560
Skin and soft tissues 39 | 18,114
Urinary Tract 39 | 18,443
Digestive Tract 38 | 18,472
Liver and Pancreas 38 | 18,135
Male tissues 38 | 17,968
Respiratory system 38 | 17,483
Cardiovascular System 37 | 17,957

Target Family

Epigenetic 12 | 242
Non-IDG 12 | 11,969
Transcription Factor 8 | 1,400
Enzyme 5 | 4,146
Kinase 1 | 634
TF/Epigenetic 1 | 38

GO Process

chromatin organization 39 | 39
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ribosomal biogenesis protein LAS1L LAS1L Tdark Non-IDG -0.45120 2.84 94
Histone-lysine N-methyltransferase SUV39H1 SUV39H1 Tchem Epigenetic -2.21810 149.4 267
DNA-binding protein SATB1 SATB1 Tbio Transcription Factor -2.24334 197.9 293
Histone deacetylase 8 HDAC8 Tclin Epigenetic -2.36549 229.4 425
Protein-arginine deiminase type-4 PADI4 Tchem Enzyme -2.43138 281.8 279
Protein-arginine deiminase type-3 PADI3 Tchem Enzyme -1.62226 40.0 40
Actin-like protein 6B ACTL6B Tbio Non-IDG -0.79164 6.22 112
Zinc finger protein 462 ZNF462 Tdark Non-IDG -0.54422 4.01 23
NAD-dependent protein deacetylase sirtuin-1 SIRT1 Tchem Epigenetic -3.43962 2958.6 656
Variable charge X-linked protein 1 VCX Tbio Non-IDG -1.48218 30.0 45