Development Level

Tbio 3 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal body wall morphology 1 | 9
abnormal embryo development 1 | 7
abnormal embryo size 1 | 220
abnormal eyelid fusion 1 | 3
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal limb morphology 1 | 13
anophthalmia 1 | 33
decreased body length 1 | 101
microphthalmia 1 | 26
polydactyly 1 | 7
preweaning lethality, complete... 1 | 979
protruding tongue 1 | 3

Disease

Carcinoma 4 | 11,493
osteosarcoma 4 | 7,950
Cancer 3 | 2,499
Hypoplastic mandible condyle 3 | 275
Mandibular hypoplasia 3 | 275
Micrognathism 3 | 275
Narrow thorax 3 | 53
ovarian cancer 3 | 8,520
Acquired scoliosis 2 | 281
Autosomal recessive predisposition 2 | 1,442
Big calvaria 2 | 147
Breast cancer 2 | 3,578
Cleft Palate 2 | 271
Concave bridge of nose 2 | 195
Congenital hypoplasia of radius 2 | 23
Curvature of spine 2 | 282
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Flat face 2 | 52
Frequent fractures 2 | 53
Hypogonadism 2 | 173
Hypoplastic feet 2 | 66
Hypoplastic iliac wing 2 | 19
Hypoplastic scapulae 2 | 14
Increased fracture rate 2 | 53
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Kidney cancer 2 | 2,613
Micromelia 2 | 58
Osteoarthritis 2 | 184
Polyhydramnios 2 | 108
Radial ray hypoplasia 2 | 23
Short hands 2 | 50
Short limb dwarfism, disproportionate 2 | 22
Short neck 2 | 140
Short ribs 2 | 30
Short stature 2 | 531
Varying degree of multiple fractures 2 | 53
atypical teratoid / rhabdoid tumor 2 | 5,112
ependymoma 2 | 4,679
lung adenocarcinoma 2 | 2,716
lung cancer 2 | 4,740
psoriasis 2 | 6,694
tuberculosis and treatment for 6 months 2 | 409
46, XX Testicular Disorders of Sex Development 1 | 3
46,XY partial gonadal dysgenesis 1 | 9
46,Xx Sex Reversal 1 1 | 3
Abnormal enchondral ossification 1 | 3
Abnormal foot bone ossification 1 | 3
Abnormal maturation of foot bones 1 | 3
Abnormal ossification involving bones of the feet 1 | 3
Abnormal sex determination 1 | 11
Abnormality of male internal genitalia 1 | 4
Abnormality of the labia 1 | 9
Abnormality of the scrotum 1 | 9
Achondrogenesis 1 | 6
Aplasia/Hypoplasia of the lungs 1 | 13
Barrel chest 1 | 12
Beading of ribs 1 | 6
Bifid scrotum 1 | 16
Broad fingernails 1 | 3
Bullet vertebral body 1 | 17
Campomelic dysplasia 1 | 7
Congenital Hand Deformities 1 | 8
Congenital hypoplasia of clavicle 1 | 18
Congenital hypoplasia of femur 1 | 8
Cupped ribs 1 | 3
Decreased calcification of skull 1 | 10
Defect of skull ossification 1 | 10
Degenerative disc disease 1 | 35
Elevated follicle stimulating hormone 1 | 15
Elevated luteinizing hormone 1 | 14
Exostosis 1 | 15
Female external genitalia in males 1 | 13
Flared ribs 1 | 3
Hand Deformities, Congenital 1 | 8
Hypoplastic cervical vertebrae 1 | 3
Hypoplastic inferior ilia 1 | 3
Oligodontia-Colorectal Cancer Syndrome 1 | 1
Ovoid vertebral bodies 1 | 17
Pierre Robin Syndrome 1 | 11
Protuberant abdomen 1 | 16
Pseudotumor cerebri 1 | 3
Radial deviation of the 3rd finger 1 | 4
Second finger clinodactyly 1 | 5
Sex reversal 1 | 10
Short femoral neck 1 | 15
Short hallux 1 | 16
Short limb dwarfism recognizable at birth 1 | 9
Short middle phalanges 1 | 12
Short stature, disproportionate 1 | 9
Short stature, severe disproportionate 1 | 9
Shortening of all phalanges of fingers 1 | 2
Spade-like hand 1 | 16
Tibial bowing 1 | 19
True Hermaphroditism (disorder) 1 | 4
Upper airway obstruction 1 | 6
Urogenital sinus anomaly 1 | 15
XX males 1 | 3

Tissue

Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678
Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192

Target Family

Non-IDG 3 | 12,091
Transcription Factor 1 | 1,400

GO Process

chondrocyte differentiation in... 4 | 4
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcription factor SOX-9 SOX9 Tbio Transcription Factor -3.14522 1332.4 657
Indian hedgehog protein IHH Tbio Non-IDG -2.61880 417.4 375
Axin-2 AXIN2 Tchem Non-IDG -2.44870 241.5 237
Thyroid receptor-interacting protein 11 TRIP11 Tbio Non-IDG -1.41760 28.7 62