Development Level

Tbio 27 | 11,651
Tchem 5 | 1,388
Tclin 3 | 612
Tdark 1 | 6,593

IMPC Phenotype

preweaning lethality, complete... 4 | 979
embryonic lethality prior to t... 3 | 278
abnormal embryo size 2 | 220
abnormal heart morphology 2 | 162
decreased bone mineral content 2 | 151
decreased vertical activity 2 | 208
enlarged heart 2 | 210
abnormal body wall morphology 1 | 9
abnormal brain morphology 1 | 13
abnormal kidney morphology 1 | 65
abnormal locomotor behavior 1 | 24
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
cataract 1 | 92
cleft palate 1 | 8
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged kidney 1 | 14
hydroencephaly 1 | 14
increased circulating alkaline... 1 | 122
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased startle reflex 1 | 112
prenatal lethality prior to he... 1 | 87
small heart 1 | 10
small testis 1 | 58

Disease

Carcinoma 29 | 11,493
ovarian cancer 24 | 8,519
glioblastoma 23 | 5,792
Cancer 20 | 2,499
atypical teratoid / rhabdoid tumor 20 | 5,112
adult high grade glioma 19 | 3,801
osteosarcoma 19 | 7,950
psoriasis 19 | 6,694
Astrocytoma, Pilocytic 18 | 3,081
medulloblastoma, large-cell 18 | 6,241
ependymoma 17 | 4,679
lung cancer 17 | 4,740
malignant mesothelioma 15 | 3,232
Breast cancer 12 | 3,577
Short stature 12 | 531
oligodendroglioma 12 | 2,850
Cleft Palate 10 | 271
Orbital separation excessive 10 | 244
astrocytic glioma 10 | 2,597
group 3 medulloblastoma 10 | 4,104
invasive ductal carcinoma 10 | 2,950
pancreatic cancer 10 | 2,398
Osteoporosis 9 | 363
colon cancer 9 | 1,478
non-small cell lung cancer 9 | 2,890
pituitary cancer 9 | 1,972
Concave bridge of nose 8 | 195
Depressed nasal bridge 8 | 195
Depressed nasal root/bridge 8 | 195
Hypoplastic mandible condyle 8 | 275
Hypotrophic malar bone 8 | 129
Malar flattening 8 | 129
Mandibular hypoplasia 8 | 275
Micrognathism 8 | 275
interstitial cystitis 8 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,954
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,290
Decreased projection of maxilla 7 | 66
Deficiency of upper jaw bones 7 | 66
Exophthalmos 7 | 112
Hypoplasia of the maxilla 7 | 66
Hypoplastic feet 7 | 66
Hypotrophic maxilla 7 | 66
Maxillary retrognathia 7 | 66
Prominent eyes 7 | 96
Prominent globes 7 | 96
Protruding eyes 7 | 96
Retrusion of upper jaw bones 7 | 66
cutaneous lupus erythematosus 7 | 1,057
ductal carcinoma in situ 7 | 1,744
lung adenocarcinoma 7 | 2,716
primitive neuroectodermal tumor 7 | 3,035
subependymal giant cell astrocytoma 7 | 2,287
Acquired scoliosis 6 | 281
Autosomal recessive predisposition 6 | 1,442
Brachydactyly 6 | 156
Cleft Lip 6 | 141
Cognitive delay 6 | 608
Congenital deafness 6 | 185
Curvature of spine 6 | 282
Deafness 6 | 198
Decreased projection of midface 6 | 105
Global developmental delay 6 | 608
Hearing Loss, Partial 6 | 185
Hypotrophic midface 6 | 105
Low set ears 6 | 181
Lung Neoplasms 6 | 232
Mental and motor retardation 6 | 608
Midface retrusion 6 | 105
Osteoarthritis 6 | 184
Small midface 6 | 105
cystic fibrosis 6 | 1,695
hearing impairment 6 | 199
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
lung carcinoma 6 | 2,843
ulcerative colitis 6 | 1,819
Abnormal skeletal development 5 | 60
Anteverted nostril 5 | 191
Arthritis, Rheumatoid 5 | 174
Craniofacial Abnormalities 5 | 151
Cryptorchidism 5 | 296
High forehead 5 | 102
Hypodontia 5 | 81
Kidney cancer 5 | 2,613
Micromelia 5 | 58
Muscle hypotonia 5 | 571
Narrow thorax 5 | 53
Osteochondrodysplasias 5 | 72
Pick disease 5 | 1,894
Platyspondyly 5 | 56
Rhizomelia 5 | 25
Schizophrenia 5 | 1,160
Tall forehead 5 | 102
active Crohn's disease 5 | 922
gastric carcinoma 5 | 807
group 4 medulloblastoma 5 | 1,855
primary pancreatic ductal adenocarcinoma 5 | 1,108
Alzheimer's disease 4 | 658
adrenocortical carcinoma 4 | 1,428
astrocytoma 4 | 1,146

Tissue

Endocrine System 36 | 18,159
Male tissues 36 | 17,142
Digestive Tract 35 | 17,369
Female tissues 35 | 17,400
Liver and Pancreas 35 | 16,750
Skin and soft tissues 35 | 17,230
Urinary Tract 35 | 16,678
Respiratory system 34 | 16,393
Blood and immune system 33 | 16,909
Nervous System 33 | 16,725
Cardiovascular System 32 | 15,192

Target Family

Non-IDG 16 | 12,091
Transcription Factor 14 | 1,400
Kinase 4 | 634
Enzyme 1 | 4,145
GPCR 1 | 408

GO Process

chondrocyte differentiation 36 | 36
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Amelogenin, X isoform AMELX Tbio Non-IDG -2.84702 695.0 136
Runt-related transcription factor 3 RUNX3 Tbio Transcription Factor -2.71721 536.2 438
Myocyte-specific enhancer factor 2D MEF2D Tbio Transcription Factor -1.96264 88.6 323
Transforming growth factor beta-1 TGFB1 Tchem Non-IDG -3.84680 5672.0 1222
Collagen alpha-1(II) chain COL2A1 Tbio Non-IDG -2.89229 724.4 424
Zinc finger protein GLI2 GLI2 Tchem Transcription Factor -2.58228 355.0 196
Bone morphogenetic protein 4 BMP4 Tchem Non-IDG -3.21660 1658.5 540
Myocyte-specific enhancer factor 2C MEF2C Tbio Transcription Factor -2.30705 184.5 974
Protein NOV homolog NOV Tbio Non-IDG -2.17716 167.6 275
Homeobox protein SIX2 SIX2 Tbio Transcription Factor -1.83196 63.4 132