Development Level

Tbio 27 | 10,625
Tchem 5 | 1,890
Tclin 3 | 602
Tdark 1 | 7,003

IMPC Term

preweaning lethality, complete... 4 | 633
embryonic lethality prior to t... 3 | 187
abnormal embryo size 2 | 112
enlarged heart 2 | 111
abnormal body wall morphology 1 | 7
abnormal forebrain development 1 | 18
abnormal heart morphology 1 | 51
abnormal hindbrain development 1 | 24
abnormal midbrain development 1 | 22
abnormal motor learning 1 | 4
abnormal neural tube closure 1 | 37
abnormal pelvic girdle bone mo... 1 | 11
abnormal retinal vasculature m... 1 | 15
abnormal seminal vesicle morph... 1 | 47
abnormal testis morphology 1 | 30
cataract 1 | 26
cleft palate 1 | 6
decreased KLRG1-positive T-hel... 1 | 2
decreased bone mineral content 1 | 157
decreased circulating choleste... 1 | 85
decreased circulating free fat... 1 | 39
decreased circulating insulin ... 1 | 75
decreased lean body mass 1 | 195
decreased lumbar vertebrae num... 1 | 62
decreased startle reflex 1 | 48
embryonic lethality prior to o... 1 | 148
immune system phenotype 1 | 17
increased circulating alkaline... 1 | 119
increased grip strength 1 | 83
increased respiratory quotient 1 | 12
increased startle reflex 1 | 38
prenatal lethality prior to he... 1 | 64
preweaning lethality, incomple... 1 | 260
short tibia 1 | 82
small testis 1 | 37

Disease

ovarian cancer 24 | 8,492
glioblastoma 22 | 5,572
osteosarcoma 19 | 7,933
medulloblastoma, large-cell 18 | 6,234
pilocytic astrocytoma 18 | 3,086
psoriasis 18 | 6,685
atypical teratoid / rhabdoid tumor 17 | 4,369
pediatric high grade glioma 17 | 2,712
Cancer 16 | 2,346
lung cancer 16 | 4,473
malignant mesothelioma 13 | 3,163
Breast cancer 11 | 3,099
oligodendroglioma 11 | 2,849
invasive ductal carcinoma 10 | 2,950
non-small cell lung cancer 9 | 2,798
pancreatic cancer 9 | 2,300
Cleft palate 8 | 125
colon cancer 8 | 1,475
ependymoma 8 | 2,514
interstitial cystitis 8 | 2,299
pituitary cancer 8 | 1,972
posterior fossa group A ependymoma 8 | 1,511
sonic hedgehog group medulloblastoma 8 | 1,482
Osteoporosis 7 | 259
astrocytic glioma 7 | 2,241
cutaneous lupus erythematosus 7 | 1,056
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
subependymal giant cell astrocytoma 7 | 2,287
Carcinoma 6 | 2,147
Cleft Lip 6 | 91
ductal carcinoma in situ 6 | 1,745
group 4 medulloblastoma 6 | 1,875
lung adenocarcinoma 6 | 2,714
lung carcinoma 6 | 2,844
primitive neuroectodermal tumor 6 | 3,031
ulcerative colitis 6 | 2,087
Lung Neoplasms 5 | 171
Pick disease 5 | 1,893
active Crohn's disease 5 | 918
adult high grade glioma 5 | 2,148
astrocytoma 5 | 1,493
cystic fibrosis 5 | 1,670
gastric carcinoma 5 | 832
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
primary pancreatic ductal adenocarcinoma 5 | 1,271
Alzheimer's disease 4 | 644
Ankylosis 4 | 25
Atopic dermatitis 4 | 944
Craniofacial Abnormalities 4 | 147
Craniosynostosis 4 | 47
Degenerative polyarthritis 4 | 93
Endometriosis 4 | 535
Lipoma 4 | 19
Mammary Neoplasms 4 | 410
Osteoarthritis 4 | 96
Periodontal disease 4 | 37
Rheumatoid Arthritis 4 | 1,171
Root resorption 4 | 21
Tooth agenesis 4 | 38
active ulcerative colitis 4 | 477
adrenocortical carcinoma 4 | 1,427
breast carcinoma 4 | 1,614
group 3 medulloblastoma 4 | 2,254
posterior fossa group B ependymoma 4 | 1,530
tuberculosis 4 | 1,563
Achondroplasia 3 | 20
Adenocarcinoma 3 | 115
Adenoma 3 | 165
Arthritis 3 | 248
Brachydactyly 3 | 52
Chondrosarcoma 3 | 24
Cleidocranial dysplasia 3 | 10
Colorectal Neoplasms 3 | 217
Degenerative disc disease 3 | 28
Fibrodysplasia ossificans progressiva 3 | 17
Holoprosencephaly 3 | 52
Kidney disease 3 | 397
Obesity 3 | 616
Osteonecrosis 3 | 25
Parkinson's disease 3 | 364
Polydactyly 3 | 93
Schizophrenia 3 | 503
Synostosis 3 | 18
Uremia 3 | 19
atypical teratoid/rhabdoid tumor 3 | 1,095
diabetes mellitus 3 | 1,663
interstitial lung disease 3 | 292
medulloblastoma 3 | 1,524
nasopharyngeal carcinoma 3 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
Diabetes Mellitus, Non-Insulin-Dependent 2 | 161
Eosinophilia 2 | 65
Hyperplasia 2 | 26
IGA Glomerulonephritis 2 | 454
Polycystic Ovary Syndrome 2 | 335
Spontaneous abortion 2 | 108
Type 2 diabetes mellitus 2 | 192
Vascular disease 2 | 281
progressive supranuclear palsy 2 | 674

Tissue

Female tissues 36 | 18,647
Cardiovascular System 35 | 17,958
Digestive Tract 35 | 18,473
Endocrine System 35 | 18,512
Male tissues 35 | 17,969
Nervous System 35 | 18,561
Skin and soft tissues 35 | 18,115
Urinary Tract 35 | 18,444
Blood and immune system 34 | 17,995
Liver and Pancreas 34 | 18,136
Respiratory system 34 | 17,484

Target Family

Non-IDG 17 | 11,969
Transcription Factor 13 | 1,400
Kinase 4 | 634
Enzyme 1 | 4,146
GPCR 1 | 408

GO Process

chondrocyte differentiation 36 | 36
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myocyte-specific enhancer factor 2D MEF2D Tbio Transcription Factor -1.92983 79.1 279
Collagen alpha-1(II) chain COL2A1 Tbio Non-IDG -2.86562 689.3 377
Runt-related transcription factor 3 RUNX3 Tbio Transcription Factor -2.67643 492.3 375
High mobility group protein HMGI-C HMGA2 Tbio Transcription Factor -3.23506 1667.7 216
Cyclic AMP-responsive element-binding protein 3-like protein 2 CREB3L2 Tbio Transcription Factor -2.48834 296.9 147
Musculoskeletal embryonic nuclear protein 1 MUSTN1 Tdark Non-IDG -1.92289 80.8 0
Runt-related transcription factor 2 RUNX2 Tbio Transcription Factor -3.35244 2146.2 588
Basic helix-loop-helix transcription factor scleraxis SCX Tbio Transcription Factor -2.82744 344.1 42
Transforming growth factor beta-1 TGFB1 Tchem Non-IDG -3.82684 20956.6 961
Sorting nexin-19 SNX19 Tbio Non-IDG -0.54269 3.15 68