Development Level

Tbio 10 | 11,651
Tchem 3 | 1,388
Tdark 1 | 6,593

IMPC Phenotype

abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal gait 1 | 69
abnormal tail movements 1 | 12
decreased body weight 1 | 161
decreased lean body mass 1 | 135
increased body weight 1 | 25
increased startle reflex 1 | 112
kinked tail 1 | 2
mammalian phenotype 1 | 17
preweaning lethality, complete... 1 | 979

Disease

ovarian cancer 13 | 8,520
Carcinoma 11 | 11,493
glioblastoma 10 | 5,792
osteosarcoma 9 | 7,950
pancreatic cancer 9 | 2,398
Breast cancer 8 | 3,578
non-small cell lung cancer 8 | 2,890
primary pancreatic ductal adenocarcinoma 8 | 1,109
cystic fibrosis 7 | 1,696
invasive ductal carcinoma 7 | 2,951
Astrocytoma, Pilocytic 6 | 3,081
Brachydactyly 6 | 156
atypical teratoid / rhabdoid tumor 6 | 5,112
ependymoma 6 | 4,679
lung adenocarcinoma 6 | 2,716
malignant mesothelioma 6 | 3,232
medulloblastoma, large-cell 6 | 6,241
pediatric high grade glioma 6 | 1,064
Autosomal recessive predisposition 5 | 1,442
Cancer 5 | 2,499
Cleft Palate 5 | 271
Short stature 5 | 531
gastric carcinoma 5 | 807
interstitial cystitis 5 | 2,312
pituitary cancer 5 | 1,972
Craniofacial Abnormalities 4 | 151
Osteoarthritis 4 | 184
X-linked cerebral adrenoleukodystrophy 4 | 116
acute quadriplegic myopathy 4 | 1,158
diabetes mellitus 4 | 1,728
ductal carcinoma in situ 4 | 1,745
lung cancer 4 | 4,740
oligodendroglioma 4 | 2,850
psoriasis 4 | 6,694
Concave bridge of nose 3 | 195
Depressed nasal bridge 3 | 195
Depressed nasal root/bridge 3 | 195
Heart conduction disease 3 | 83
Hypoplastic feet 3 | 66
Hypoplastic mandible condyle 3 | 275
Kidney cancer 3 | 2,613
Knee joint valgus deformity 3 | 56
Mandibular hypoplasia 3 | 275
Micrognathism 3 | 275
Orbital separation excessive 3 | 244
Osteochondrodysplasias 3 | 72
Pick disease 3 | 1,894
Platyspondyly 3 | 56
Syndactyly 3 | 88
Uranostaphyloschisis 3 | 167
adult high grade glioma 3 | 3,801
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
group 3 medulloblastoma 3 | 4,104
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
juvenile dermatomyositis 3 | 1,187
lung carcinoma 3 | 2,843
primary Sjogren syndrome 3 | 735
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 1,819
Abnormal skeletal development 2 | 60
Bilateral fifth finger clinodactyly 2 | 110
Breast Neoplasms 2 | 445
Broad flat nasal bridge 2 | 236
Byzanthine arch palate 2 | 194
Congenital Epicanthus 2 | 177
Congenital deafness 2 | 185
Congenital heart disease 2 | 93
Craniosynostosis 2 | 74
Curvature of little finger 2 | 110
Deafness 2 | 198
Degenerative polyarthritis 2 | 115
Exophthalmos 2 | 112
Flat face 2 | 52
Frontal bossing 2 | 157
Hearing Loss, Partial 2 | 185
High forehead 2 | 102
Liver cancer 2 | 604
Mammary Neoplasms 2 | 425
Micromelia 2 | 58
Microstomia 2 | 78
Nasal bridge wide 2 | 236
Osteoporosis 2 | 363
Polycystic ovary syndrome 2 | 360
Prominent eyes 2 | 96
Prominent globes 2 | 96
Protruding eyes 2 | 96
Short metacarpal 2 | 43
Short nose 2 | 132
Small nose 2 | 132
Tall forehead 2 | 102
Thin lips 2 | 49
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
hearing impairment 2 | 199
medulloblastoma 2 | 720
tuberculosis 2 | 2,010

Tissue

Blood and immune system 14 | 16,909
Digestive Tract 14 | 17,369
Endocrine System 14 | 18,159
Female tissues 14 | 17,400
Liver and Pancreas 14 | 16,750
Male tissues 14 | 17,142
Nervous System 14 | 16,725
Respiratory system 14 | 16,393
Skin and soft tissues 14 | 17,230
Urinary Tract 14 | 16,678
Cardiovascular System 13 | 15,192

Target Family

Enzyme 5 | 4,145
Kinase 3 | 634
Non-IDG 3 | 12,091
Transcription Factor 3 | 1,400

GO Process

chondrocyte development 14 | 14
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Inositol monophosphatase 3 IMPAD1 Tdark Enzyme -0.78606 4.97 79
Homeobox protein MSX-2 MSX2 Tbio Transcription Factor -2.43910 277.8 324
Eukaryotic translation initiation factor 2-alpha kinase 3 EIF2AK3 Tchem Kinase -3.05781 896.8 450
Runt-related transcription factor 2 RUNX2 Tbio Transcription Factor -3.40091 2392.3 631
Bone morphogenetic protein receptor type-2 BMPR2 Tchem Kinase -2.66587 458.1 390
Chondroitin sulfate synthase 1 CHSY1 Tbio Enzyme -1.69082 48.5 101
Fibroblast growth factor 18 FGF18 Tbio Non-IDG -1.89822 84.6 146
Collagen alpha-1(XI) chain COL11A1 Tbio Non-IDG -2.15516 138.4 96
Extracellular sulfatase Sulf-2 SULF2 Tbio Enzyme -1.74398 67.0 221
Extracellular sulfatase Sulf-1 SULF1 Tbio Enzyme -1.90276 92.2 61