Development Level

Tbio 11 | 11,445
Tchem 3 | 1,598
Tclin 2 | 613
Tdark 1 | 6,588

IMPC Phenotype

decreased circulating unsatura... 1 | 2
hypoactivity 1 | 132
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased mean corpuscular vol... 1 | 92
preweaning lethality, incomple... 1 | 499
small adrenal glands 1 | 16

Disease

ovarian cancer 14 | 8,520
Carcinoma 10 | 11,493
Atherosclerosis 8 | 291
Autosomal recessive predisposition 7 | 1,442
Coronary artery disease 7 | 268
lung cancer 7 | 4,740
lung carcinoma 7 | 2,843
osteosarcoma 7 | 7,950
pancreatic cancer 7 | 2,398
psoriasis 7 | 6,694
Hypertensive disease 6 | 292
Lipid metabolism disorder 6 | 114
Obesity 6 | 678
diabetes mellitus 6 | 1,728
non-small cell lung cancer 6 | 2,890
Breast cancer 5 | 3,578
Hypercholesterolemia 5 | 44
Hypertension 5 | 396
Kidney cancer 5 | 2,613
ductal carcinoma in situ 5 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
invasive ductal carcinoma 5 | 2,951
lung adenocarcinoma 5 | 2,716
Astrocytoma, Pilocytic 4 | 3,081
Cancer 4 | 2,499
Fatty liver disease 4 | 103
Heart disease 4 | 306
Hepatomegaly 4 | 285
Hypercholesterolemia, Familial 4 | 23
Hyperlipidemia 4 | 43
Serum cholesterol raised 4 | 22
cystic fibrosis 4 | 1,696
ependymoma 4 | 4,679
glioblastoma 4 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
medulloblastoma, large-cell 4 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Arcus Senilis 3 | 11
Cardiovascular system disease 3 | 246
Cerebellar Ataxia 3 | 304
Cerebrovascular disease 3 | 238
Coronary Disease 3 | 25
Coronary heart disease 3 | 16
Deglutition Disorders 3 | 132
Down syndrome 3 | 499
Dull intelligence 3 | 645
Dyslipidemias 3 | 27
Dyspnea 3 | 76
Epilepsy 3 | 792
Familial hypercholesterolemia - homozygous 3 | 7
Hyperlipidemias 3 | 17
Hyperlipoproteinemia Type II 3 | 12
Increase in blood pressure 3 | 119
Intellectual disability 3 | 1,016
Kidney disease 3 | 430
Liver disease 3 | 237
Low density lipoprotein increased 3 | 8
Low intelligence 3 | 645
Melanoma 3 | 711
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Niemann-Pick disease 3 | 14
Poor school performance 3 | 645
Prostatic Neoplasms 3 | 495
Sea-Blue Histiocyte Syndrome 3 | 7
Skin cancer 3 | 469
Splenomegaly 3 | 190
Steatohepatitis 3 | 44
adrenocortical carcinoma 3 | 1,428
pancreatic carcinoma 3 | 562
ulcerative colitis 3 | 1,819
Acquired metabolic disease 2 | 336
Alcoholic Intoxication, Chronic 2 | 289
Anemia 2 | 365
Angina Pectoris 2 | 32
Arcus juvenilis 2 | 5
Cardiovascular Diseases 2 | 59
Clouding of corneal stroma 2 | 50
Corneal Opacity 2 | 53
Dementia 2 | 175
Dysarthria 2 | 192
Dystonia 2 | 164
Dystonic disease 2 | 106
Gaucher disease type 1 2 | 180
Hyperinsulinism 2 | 133
Liver Cirrhosis, Experimental 2 | 769
Liver diseases 2 | 87
Loss of speech 2 | 16
Lung disease 2 | 142
Malabsorption 2 | 82
Muscle Spasticity 2 | 195
Myocardial Infarction 2 | 151
Neonatal Jaundice 2 | 30
Neurodegenerative disease 2 | 414
Prolonged neonatal jaundice 2 | 17
Proteinuria 2 | 144
Psychotic Disorders 2 | 151
Stomach Neoplasms 2 | 300
Sudden Cardiac Death 2 | 29

Tissue

Endocrine System 17 | 18,159
Digestive Tract 16 | 17,369
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678
Blood and immune system 15 | 16,909
Cardiovascular System 14 | 15,192
Nervous System 14 | 16,725
Respiratory system 14 | 16,393

Target Family

Non-IDG 15 | 12,091
Enzyme 1 | 4,145
Ion Channel 1 | 344

GO Process

cholesterol transport 17 | 17
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
SCP2 sterol-binding domain-containing protein 1 SCP2D1 Tdark Non-IDG 0.09 0.68 34
Niemann-Pick C1-like protein 1 NPC1L1 Tclin Non-IDG -2.33312 222.7 139
Niemann-Pick C1 protein NPC1 Tbio Non-IDG -2.71962 551.3 284
Cholesteryl ester transfer protein CETP Tchem Non-IDG -3.20658 1755.9 264
Protein ARV1 ARV1 Tbio Non-IDG -1.32971 21.5 68
Phosphatidylcholine-sterol acyltransferase LCAT Tbio Enzyme -2.52851 336.6 270
Apolipoprotein B-100 APOB Tchem Non-IDG -4.00022 10024.1 856
Low-density lipoprotein receptor LDLR Tchem Non-IDG -3.06808 938.9 585
Platelet glycoprotein 4 CD36 Tbio Non-IDG -2.63884 376.0 1155
StAR-related lipid transfer protein 3 STARD3 Tbio Non-IDG -1.61721 39.4 37