Development Level

Tbio 35 | 11,445
Tchem 22 | 1,598
Tclin 2 | 613
Tdark 1 | 6,588

IMPC Phenotype

increased circulating choleste... 4 | 66
preweaning lethality, incomple... 4 | 499
abnormal lens morphology 3 | 81
cataract 3 | 92
decreased circulating serum al... 3 | 82
increased circulating alkaline... 3 | 122
preweaning lethality, complete... 3 | 979
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
hypoactivity 2 | 132
increased circulating HDL chol... 2 | 80
increased circulating triglyce... 2 | 42
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
increased total body fat amoun... 2 | 134
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal heart left ventricle ... 1 | 16
abnormal kidney morphology 1 | 65
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal tooth morphology 1 | 24
cardiovascular system phenotyp... 1 | 36
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased cardiac muscle contr... 1 | 11
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating fructosa... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased circulating unsatura... 1 | 2
decreased erythrocyte cell num... 1 | 62
decreased heart rate 1 | 18
decreased heart weight 1 | 27
decreased mean corpuscular vol... 1 | 79
decreased red blood cell distr... 1 | 41
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged spleen 1 | 41
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased body weight 1 | 25
increased circulating LDL chol... 1 | 13
increased circulating amylase ... 1 | 25
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating free fat... 1 | 20
increased circulating iron lev... 1 | 30
increased circulating unsatura... 1 | 1
increased exploration in new e... 1 | 8
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 36
increased startle reflex 1 | 112
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38
small adrenal glands 1 | 16
thin ventricular wall 1 | 24
vertebral fusion 1 | 23

Disease

Carcinoma 35 | 11,493
Atherosclerosis 32 | 291
psoriasis 30 | 6,694
osteosarcoma 29 | 7,950
ovarian cancer 28 | 8,520
Lipid metabolism disorder 24 | 114
Coronary artery disease 23 | 268
pancreatic ductal adenocarcinoma liver metastasis 23 | 1,962
diabetes mellitus 21 | 1,728
lung cancer 21 | 4,740
Obesity 19 | 678
invasive ductal carcinoma 18 | 2,951
medulloblastoma, large-cell 18 | 6,241
glioblastoma 17 | 5,792
lung carcinoma 16 | 2,843
Astrocytoma, Pilocytic 15 | 3,081
Autosomal recessive predisposition 15 | 1,442
Hypercholesterolemia, Familial 15 | 23
atypical teratoid / rhabdoid tumor 15 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
malignant mesothelioma 15 | 3,232
pancreatic cancer 15 | 2,398
adult high grade glioma 14 | 3,801
ductal carcinoma in situ 14 | 1,745
Liver Cirrhosis, Experimental 13 | 769
interstitial cystitis 13 | 2,312
Cardiovascular system disease 12 | 246
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
Breast cancer 11 | 3,578
Cancer 11 | 2,499
Hypercholesterolemia 11 | 44
adrenocortical carcinoma 11 | 1,428
Heart disease 10 | 306
Hepatomegaly 10 | 285
Hyperlipidemia 10 | 43
Hyperlipoproteinemia Type II 10 | 12
Schizophrenia 10 | 1,160
ependymoma 10 | 4,679
lung adenocarcinoma 10 | 2,716
Fatty liver disease 9 | 103
Hypertensive disease 9 | 292
Kidney cancer 9 | 2,613
Kidney disease 9 | 430
Serum cholesterol raised 9 | 22
Vascular disease 9 | 319
group 3 medulloblastoma 9 | 4,104
non-small cell lung cancer 9 | 2,890
oligodendroglioma 9 | 2,850
primitive neuroectodermal tumor 9 | 3,035
subependymal giant cell astrocytoma 9 | 2,287
ulcerative colitis 9 | 1,819
Hyperlipoproteinemia Type IIa 8 | 11
Hypertension 8 | 396
Metabolic syndrome X 8 | 52
active Crohn's disease 8 | 922
breast carcinoma 8 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
tuberculosis 8 | 2,010
Cholestasis 7 | 155
Down syndrome 7 | 499
Hypertriglyceridemia result 7 | 37
Splenomegaly 7 | 190
Xanthomatosis 7 | 12
active ulcerative colitis 7 | 764
colon cancer 7 | 1,478
group 4 medulloblastoma 7 | 1,855
nephrosclerosis 7 | 333
Arcus Senilis 6 | 11
Cerebrovascular disease 6 | 238
Dyslipidemias 6 | 27
Hyperlipidemias 6 | 17
Low density lipoprotein increased 6 | 8
Myocardial Infarction 6 | 151
Pancreatitis 6 | 123
Prostatic Neoplasms 6 | 495
Sitosterolemia 6 | 9
cystic fibrosis 6 | 1,696
gastric carcinoma 6 | 807
pituitary cancer 6 | 1,972
Alzheimer's disease 5 | 658
Arthritis 5 | 290
Atopic dermatitis 5 | 952
Cardiovascular Diseases 5 | 59
Chemical and Drug Induced Liver Injury 5 | 195
Fatty Liver 5 | 70
Hyperglycemia 5 | 137
Increase in blood pressure 5 | 119
Liver cancer 5 | 604
Liver disease 5 | 237
Neurodegenerative disease 5 | 414
Steatohepatitis 5 | 44
Type 2 diabetes mellitus 5 | 272
acute quadriplegic myopathy 5 | 1,158
astrocytic glioma 5 | 2,597
dermatomyositis 5 | 966
fibroadenoma 5 | 559
juvenile dermatomyositis 5 | 1,187
nasopharyngeal carcinoma 5 | 1,058
sarcoidosis 5 | 370
spina bifida 5 | 1,074

Tissue

Digestive Tract 59 | 17,369
Endocrine System 58 | 18,159
Female tissues 58 | 17,400
Liver and Pancreas 58 | 16,750
Male tissues 56 | 17,142
Skin and soft tissues 56 | 17,230
Blood and immune system 55 | 16,909
Urinary Tract 55 | 16,678
Nervous System 51 | 16,725
Respiratory system 50 | 16,393
Cardiovascular System 47 | 15,192

Target Family

Non-IDG 31 | 12,091
Enzyme 19 | 4,145
Transporter 5 | 473
Nuclear Receptor 3 | 48
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

GO Process

cholesterol homeostasis 60 | 60
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
X-box-binding protein 1 XBP1 Tchem Transcription Factor -2.90444 780.2 514
Fatty acid-binding protein, adipocyte FABP4 Tchem Non-IDG -2.73935 617.7 605
Scavenger receptor class B member 1 SCARB1 Tchem Non-IDG -2.93920 915.7 378
Diacylglycerol O-acyltransferase 2 DGAT2 Tchem Enzyme -2.07482 112.0 230
Niemann-Pick C1 protein NPC1 Tbio Non-IDG -2.71962 551.3 284
Acyl-coenzyme A synthetase ACSM3, mitochondrial ACSM3 Tbio Enzyme -1.41035 25.5 112
Signal transducer CD24 CD24 Tbio Non-IDG 0.00000 0
Mediator of RNA polymerase II transcription subunit 13 MED13 Tbio Enzyme -1.52250 26.0 53
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 GPIHBP1 Tbio Non-IDG -1.82315 79.6 104
Apolipoprotein A-V APOA5 Tbio Non-IDG -2.58826 425.0 481