Development Level

Tbio 9 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

increased circulating choleste... 3 | 66
decreased circulating serum al... 2 | 82
increased circulating alkaline... 2 | 122
abnormal lens morphology 1 | 81
abnormal tooth morphology 1 | 24
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased cardiac muscle contr... 1 | 11
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased heart rate 1 | 18
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged heart 1 | 210
enlarged spleen 1 | 41
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating amylase ... 1 | 25
increased circulating bilirubi... 1 | 16
increased circulating free fat... 1 | 20
increased circulating triglyce... 1 | 42
increased circulating unsatura... 1 | 1
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 36
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
persistence of hyaloid vascula... 1 | 33
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38

Disease

Carcinoma 7 | 11,493
psoriasis 6 | 6,694
Atherosclerosis 5 | 291
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
ovarian cancer 5 | 8,520
group 3 medulloblastoma 4 | 4,104
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
malignant mesothelioma 4 | 3,232
osteosarcoma 4 | 7,950
Alzheimer's disease 3 | 658
Breast cancer 3 | 3,578
Lipid metabolism disorder 3 | 114
diabetes mellitus 3 | 1,728
glioblastoma 3 | 5,792
invasive ductal carcinoma 3 | 2,951
medulloblastoma, large-cell 3 | 6,241
oligodendroglioma 3 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Alzheimer Disease 2 | 83
Astrocytoma, Pilocytic 2 | 3,081
Autosomal recessive predisposition 2 | 1,442
Breast Neoplasms 2 | 445
Cardiovascular system disease 2 | 246
Carotid stenosis 2 | 5
Cholestasis 2 | 155
Coronary artery disease 2 | 268
Hepatomegaly 2 | 285
Hypercholesterolemia 2 | 44
Hypercholesterolemia, Familial 2 | 23
Hypertriglyceridemia result 2 | 37
Kidney cancer 2 | 2,613
Liver Cirrhosis 2 | 181
Liver disease 2 | 237
Low density lipoprotein increased 2 | 8
Mammary Neoplasms 2 | 425
Obesity 2 | 678
Seizures 2 | 596
Serum cholesterol raised 2 | 22
Splenomegaly 2 | 190
Steatorrhea 2 | 34
Syndromic X-linked intellectual disability Snyder type 2 | 21
alpha-methylacyl-CoA racemase deficiency 2 | 9
astrocytic glioma 2 | 2,597
chronic rhinosinusitis 2 | 512
ependymoma 2 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung cancer 2 | 4,740
pituitary cancer 2 | 1,972
ulcerative colitis 2 | 1,819
Age related macular degeneration 1 | 72
Alcohol abuse 1 | 50
Amyloidosis 1 | 67
Aphasia 1 | 26
Blepharitis 1 | 23
Carotid Artery Diseases 1 | 11
Cellulitis of eyelid 1 | 17
Cerebrotendinous xanthomatosis 1 | 13
Cholangitis 1 | 32
Cholelithiasis 1 | 33
Congenital bile acid synthesis defect 1 | 15
Coronary Arteriosclerosis 1 | 6
Delirium 1 | 10
Dyslipidemias 1 | 27
Edema 1 | 81
Emphysema 1 | 12
Endometriosis of ovary 1 | 5
Familial hyperlipidemia 1 | 6
Hepatitis 1 | 67
Hepatolenticular Degeneration 1 | 24
High density lipoprotein decreased 1 | 10
Hyperglycemia 1 | 137
Hyperlipidemia 1 | 43
Hyperlipoproteinemia Type II 1 | 12
Hypoalphalipoproteinemias 1 | 10
Increased bilirubin level (finding) 1 | 18
Infiltrate of lung 1 | 17
Intrahepatic cholestasis 1 | 20
Kidney Failure, Chronic 1 | 46
Long tract signs 1 | 3
Lysosomal storage disease 1 | 10
Macular Degeneration, Age-Related, 1 1 | 9
Macular degeneration 1 | 65
Marijuana Abuse 1 | 31
Maturity onset diabetes mellitus in young 1 | 11
Neonatal onset 1 | 21
Neurofibrillary degeneration (morphologic abnormality) 1 | 9
Pancreatitis 1 | 123
Pancreatitis, Chronic 1 | 9
Pathological accumulation of air in tissues 1 | 10
Phencyclidine abuse 1 | 6
Plaque build-up in arteries supplying blood to heart 1 | 6
Primary cutaneous amyloidosis 1 | 29
Renal glomerular disease 1 | 12
Respiratory Distress Syndrome, Adult 1 | 40
Steatohepatitis 1 | 44
Subcutaneous nodule 1 | 53
Swayback 1 | 2
Urethral Stricture 1 | 18
maturity-onset diabetes of the young 1 | 32

Tissue

Blood and immune system 11 | 16,909
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Skin and soft tissues 11 | 17,230
Urinary Tract 10 | 16,678
Cardiovascular System 9 | 15,192
Nervous System 9 | 16,725
Respiratory system 9 | 16,393

Target Family

Enzyme 5 | 4,145
Non-IDG 5 | 12,091
Transcription Factor 1 | 1,400

GO Process

cholesterol catabolic process 11 | 11
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cholesterol 24-hydroxylase CYP46A1 Tbio Enzyme -1.84856 68.6 197
Transcriptional-regulating factor 1 TRERF1 Tbio Transcription Factor -0.69436 6.18 146
Scavenger receptor class B member 1 SCARB1 Tchem Non-IDG -2.93920 915.7 378
Cholesterol 7-alpha-monooxygenase CYP7A1 Tbio Enzyme -2.70498 494.6 94
Scavenger receptor class F member 1 SCARF1 Tbio Non-IDG -1.83307 67.9 102
Metallothionein-3 MT3 Tbio Non-IDG -2.30937 197.7 87
Sorting nexin-17 SNX17 Tbio Non-IDG -1.19414 18.3 101
Bile salt-activated lipase CEL Tchem Enzyme -2.57254 373.8 0
24-hydroxycholesterol 7-alpha-hydroxylase CYP39A1 Tbio Enzyme -0.96016 6.61 126
3-oxo-5-beta-steroid 4-dehydrogenase AKR1D1 Tbio Enzyme -1.87479 75.7 171