Development Level

Tbio 37 | 10,625
Tchem 10 | 1,890
Tdark 1 | 7,003

Collection

GPCR: IDG Consortium (Targets) 1 | 128

IMPC Phenotype

decreased circulating insulin ... 2 | 75
preweaning lethality, complete... 2 | 633
abnormal behavioral response t... 1 | 52
decreased caudal vertebrae num... 1 | 49
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
improved glucose tolerance 1 | 56
increased circulating HDL chol... 1 | 63
increased circulating total pr... 1 | 20
preweaning lethality, incomple... 1 | 260

Disease

psoriasis 33 | 6,685
Cancer 30 | 2,346
interstitial cystitis 28 | 2,299
ulcerative colitis 26 | 2,087
lung cancer 22 | 4,473
lung carcinoma 19 | 2,844
Asthma 18 | 349
Hypersensitivity 18 | 63
lung adenocarcinoma 18 | 2,714
ovarian cancer 18 | 8,491
Pneumonia 16 | 133
glioblastoma 16 | 5,572
tuberculosis 16 | 1,563
Lung disease 15 | 136
Multiple Sclerosis 15 | 498
non-small cell lung cancer 15 | 2,798
posterior fossa group A ependymoma 15 | 1,511
Arthritis 14 | 248
cutaneous lupus erythematosus 14 | 1,056
cystic fibrosis 14 | 1,670
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,956
Hypersensitivity reaction type II disease 13 | 235
adult high grade glioma 13 | 2,148
invasive ductal carcinoma 13 | 2,950
colon cancer 12 | 1,475
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,988
malignant mesothelioma 12 | 3,163
pancreatic cancer 12 | 2,300
Breast cancer 11 | 3,098
breast carcinoma 11 | 1,614
osteosarcoma 11 | 7,933
primary Sjogren syndrome 11 | 788
Atherosclerosis 10 | 275
Inflammatory bowel disease 10 | 142
Influenza 10 | 142
active Crohn's disease 10 | 918
atypical teratoid / rhabdoid tumor 10 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,289
medulloblastoma, large-cell 10 | 6,234
Atopic dermatitis 9 | 944
Dermatitis 9 | 141
Eosinophilia 9 | 65
Rheumatoid Arthritis 9 | 1,170
hepatocellular carcinoma 9 | 550
nasopharyngeal carcinoma 9 | 1,056
Allergic hypersensitivity disease 8 | 123
Coronary artery disease 8 | 240
Human immunodeficiency virus infectious disease 8 | 129
Kidney disease 8 | 397
Pulmonary Fibrosis 8 | 66
ductal carcinoma in situ 8 | 1,745
head and neck cancer 8 | 270
head and neck cancer and chronic obstructive pulmonary disease 8 | 237
juvenile dermatomyositis 8 | 1,189
periodontitis 8 | 269
pilocytic astrocytoma 8 | 3,086
sarcoidosis 8 | 368
Glomerulonephritis 7 | 36
Vascular disease 7 | 281
diabetes mellitus 7 | 1,663
gastric carcinoma 7 | 832
mucosa-associated lymphoid tissue lymphoma 7 | 480
Barrett's esophagus 6 | 185
Dermatitis, Atopic 6 | 45
Eye disease 6 | 55
Inflammation 6 | 109
Mammary Neoplasms 6 | 410
Myocardial Ischemia 6 | 169
adrenocortical carcinoma 6 | 1,427
esophageal adenocarcinoma 6 | 737
Allergic rhinitis 5 | 92
Brain Ischemia 5 | 87
Cerebrovascular disease 5 | 231
Encephalitis 5 | 54
HIV Infections 5 | 99
Keratitis 5 | 42
Malaria 5 | 140
Reperfusion Injury 5 | 84
aldosterone-producing adenoma 5 | 664
gastric cancer 5 | 436
pancreatic carcinoma 5 | 567
pituitary cancer 5 | 1,972
subependymal giant cell astrocytoma 5 | 2,287
Arsenic Poisoning 4 | 59
Common cold 4 | 63
Dermatologic disorders 4 | 65
Drug-Induced Liver Injury 4 | 118
Endometriosis 4 | 535
Heart disease 4 | 279
Human immunodeficiency virus type 1, susceptibility to 4 | 26
Hypertension 4 | 293
Liver carcinoma 4 | 217
Meningitis 4 | 46
Obesity 4 | 616
Pick disease 4 | 1,893
Status Epilepticus 4 | 85
chronic rhinosinusitis 4 | 512
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
pediatric high grade glioma 4 | 2,712
acute myeloid leukemia 3 | 785

Tissue

Digestive Tract 41 | 18,472
Blood and immune system 40 | 17,994
Liver and Pancreas 40 | 18,135
Nervous System 40 | 18,560
Endocrine System 39 | 18,511
Female tissues 39 | 18,646
Male tissues 39 | 17,968
Respiratory system 39 | 17,483
Cardiovascular System 38 | 17,957
Skin and soft tissues 38 | 18,114
Urinary Tract 38 | 18,443

Target Family

Non-IDG 42 | 11,969
GPCR 5 | 408
Kinase 1 | 634

GO Process

chemokine-mediated signaling p... 48 | 48
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Atypical chemokine receptor 3 ACKR3 Tchem GPCR -1.80879 81.4 385
C-X-C motif chemokine 2 CXCL2 Tchem Non-IDG -2.41448 214.2 170
C-X-C motif chemokine 3 CXCL3 Tbio Non-IDG -1.92093 74.7 158
C-X-C motif chemokine 11 CXCL11 Tbio Non-IDG -2.70030 491.1 279
Growth-regulated alpha protein CXCL1 Tbio Non-IDG -3.10318 1174.2 351
C-C motif chemokine 17 CCL17 Tbio Non-IDG -2.62201 455.4 279
C-C motif chemokine 3 CCL3 Tbio Non-IDG -3.15064 1348.0 518
Interleukin-8 CXCL8 Tchem Non-IDG -3.98343 9346.7 993
C-C motif chemokine 1 CCL1 Tbio Non-IDG -2.44724 261.3 157
C-X-C motif chemokine 9 CXCL9 Tbio Non-IDG -2.94746 860.6 317