Development Level

Tbio 94 | 10,625
Tchem 57 | 1,890
Tclin 53 | 602
Tdark 34 | 7,003

Collection

Eligible Ion Channel Proteins 14 | 117
Eligible non-olfactory GPCR Proteins 9 | 143

IMPC Term

decreased total body fat amoun... 7 | 186
abnormal behavior 6 | 226
decreased grip strength 5 | 123
preweaning lethality, incomple... 5 | 260
abnormal bone structure 4 | 131
decreased body weight 4 | 174
decreased circulating HDL chol... 4 | 77
decreased circulating choleste... 4 | 85
decreased lean body mass 4 | 195
hypoactivity 4 | 89
preweaning lethality, complete... 4 | 633
abnormal gait 3 | 51
decreased bone mineral content 3 | 157
decreased fasted circulating g... 3 | 49
enlarged heart 3 | 111
hyperactivity 3 | 108
impaired glucose tolerance 3 | 52
improved glucose tolerance 3 | 56
increased circulating chloride... 3 | 43
increased circulating sodium l... 3 | 71
increased lean body mass 3 | 107
short tibia 3 | 82
straub tail 3 | 26
tremors 3 | 34
abnormal behavioral response t... 2 | 52
abnormal bone mineralization 2 | 55
abnormal head morphology 2 | 10
cardiovascular system phenotyp... 2 | 35
decreased circulating LDL chol... 2 | 37
decreased circulating alkaline... 2 | 41
decreased exploration in new e... 2 | 9
decreased heart weight 2 | 44
increased bone mineral content 2 | 92
increased mean corpuscular vol... 2 | 91
increased total body fat amoun... 2 | 57
abnormal coat/hair pigmentatio... 1 | 54
abnormal heart left ventricle ... 1 | 20
abnormal heart morphology 1 | 51
abnormal liver morphology 1 | 5
abnormal locomotor activation 1 | 26
abnormal lung morphology 1 | 15
abnormal pericardium morpholog... 1 | 11
abnormal skin morphology 1 | 23
abnormal startle reflex 1 | 14
abnormal testis morphology 1 | 30
absent testes 1 | 2
cataract 1 | 26
decreased anxiety-related resp... 1 | 12
decreased body length 1 | 108
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating calcium ... 1 | 33
decreased circulating fructosa... 1 | 31
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased lumbar vertebrae num... 1 | 62
decreased neutrophil cell numb... 1 | 37
decreased prepulse inhibition 1 | 52
decreased pulmonary respirator... 1 | 4
decreased vertical activity 1 | 22
embryonic lethality prior to t... 1 | 187
enlarged stomach 1 | 2
hydrops fetalis 1 | 22
impaired pupillary reflex 1 | 14
increased blood urea nitrogen ... 1 | 44
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating alanine ... 1 | 11
increased circulating alkaline... 1 | 119
increased circulating aspartat... 1 | 17
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating fructosa... 1 | 11
increased circulating iron lev... 1 | 25
increased circulating phosphat... 1 | 24
increased circulating serum al... 1 | 25
increased eosinophil cell numb... 1 | 9
increased erythrocyte cell num... 1 | 26
increased heart weight 1 | 37
increased mean corpuscular hem... 1 | 93
increased rib number 1 | 41
increased startle reflex 1 | 38
increased vertical activity 1 | 18
lethargy 1 | 5
male infertility 1 | 62
mydriasis 1 | 9
persistence of hyaloid vascula... 1 | 22
short tail 1 | 4
small testis 1 | 37
small thymus 1 | 11
thrombocytopenia 1 | 46

Disease

medulloblastoma, large-cell 122 | 6,234
glioblastoma 119 | 5,572
oligodendroglioma 101 | 2,849
atypical teratoid / rhabdoid tumor 95 | 4,369
psoriasis 93 | 6,685
primitive neuroectodermal tumor 88 | 3,031
pilocytic astrocytoma 78 | 3,086
osteosarcoma 76 | 7,933
pediatric high grade glioma 75 | 2,712
ovarian cancer 74 | 8,484
Carcinoma 70 | 2,147
ependymoma 62 | 2,514
Schizophrenia 60 | 501
Epilepsy 57 | 346
astrocytic glioma 57 | 2,241
subependymal giant cell astrocytoma 57 | 2,287
Pick disease 55 | 1,893
lung carcinoma 55 | 2,844
astrocytoma 50 | 1,493
medulloblastoma 49 | 1,524
adult high grade glioma 46 | 2,148
lung cancer 42 | 4,466
malignant mesothelioma 40 | 3,162
Alzheimer's disease 38 | 644
posterior fossa group A ependymoma 38 | 1,511
Parkinson's disease 37 | 364
pituitary cancer 34 | 1,972
Breast cancer 33 | 3,094
Bipolar Disorder 31 | 266
sonic hedgehog group medulloblastoma 31 | 1,482
group 4 medulloblastoma 30 | 1,875
invasive ductal carcinoma 28 | 2,950
group 3 medulloblastoma 27 | 2,254
intraductal papillary-mucinous adenoma (IPMA) 27 | 2,956
Autistic Disorder 26 | 320
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,988
Cancer 24 | 2,346
atypical teratoid/rhabdoid tumor 24 | 1,095
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,289
Alcohol dependence 23 | 107
interstitial cystitis 23 | 2,299
Cocaine-Related Disorders 22 | 88
Major Depressive Disorder 22 | 106
Toxic encephalopathy 22 | 131
posterior fossa group B ependymoma 22 | 1,530
Obesity 21 | 616
Pain agnosia 20 | 99
Substance Withdrawal Syndrome 20 | 52
adrenocortical carcinoma 20 | 1,427
colon cancer 20 | 1,475
General anesthesia 19 | 53
Intellectual disability 19 | 573
Migraine 19 | 79
Seizures 19 | 95
Attention deficit hyperactivity disorder 18 | 156
diabetes mellitus 18 | 1,663
lung adenocarcinoma 17 | 2,713
Amyotrophic Lateral Sclerosis 16 | 431
Down syndrome 16 | 548
Neurodegenerative disease 16 | 383
non primary Sjogren syndrome sicca 16 | 840
Dementia 14 | 129
Huntington's disease 14 | 72
Local anesthesia 14 | 40
Pain 14 | 70
Hyperalgesia 13 | 71
Multiple Sclerosis 13 | 498
cystic fibrosis 13 | 1,665
ductal carcinoma in situ 13 | 1,745
ulcerative colitis 13 | 2,087
Hypertension 12 | 287
Status Epilepticus 12 | 85
Substance abuse 12 | 55
non-small cell lung cancer 12 | 2,798
Atopic dermatitis 11 | 944
Irritable bowel syndrome 11 | 59
Migraine Prevention 11 | 22
Neuropathy 11 | 210
Simple partial seizure 11 | 26
Tonic-clonic epilepsy 11 | 47
obsessive-compulsive disorder 11 | 34
tuberculosis 11 | 1,557
Acromegaly 10 | 40
Epilepsy, Temporal Lobe 10 | 23
Generalized anxiety disorder 10 | 29
Lennox-Gastaut syndrome 10 | 34
Narcolepsy 10 | 58
cutaneous lupus erythematosus 10 | 1,056
gastric carcinoma 10 | 832
Cerebrovascular disease 9 | 231
Epilepsy characterized by intractable complex partial seizures 9 | 28
Panic disorder 9 | 55
Peripheral Neuropathy 9 | 303
active Crohn's disease 9 | 918
aldosterone-producing adenoma 9 | 664
pancreatic cancer 9 | 2,300
Heart disease 8 | 279
Kidney disease 8 | 396
Vascular disease 8 | 281
dermatomyositis 8 | 933

Tissue

Female tissues 231 | 18,647
Urinary Tract 231 | 18,444
Nervous System 229 | 18,561
Digestive Tract 228 | 18,473
Endocrine System 227 | 18,512
Skin and soft tissues 223 | 18,115
Liver and Pancreas 222 | 18,136
Cardiovascular System 218 | 17,958
Male tissues 212 | 17,969
Blood and immune system 211 | 17,995
Respiratory system 204 | 17,484

Target Family

Non-IDG 91 | 11,971
GPCR 50 | 406
Ion Channel 46 | 341
Transporter 18 | 473
Enzyme 17 | 4,146
oGPCR 12 | 421
Kinase 4 | 634

GO Process

chemical synaptic transmission 238 | 238
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 Tchem Ion Channel -1.68717 47.7 33
Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B Tclin Ion Channel -2.21210 162.9 67
Myelin basic protein MBP Tbio Non-IDG -3.69577 5257.0 715
Gamma-aminobutyric acid receptor subunit rho-1 GABRR1 Tchem Ion Channel -1.70715 50.4 134
Pro-neuropeptide Y NPY Tbio Non-IDG -3.81741 7285.3 401
5-hydroxytryptamine receptor 6 HTR6 Tchem GPCR -2.29395 203.8 55
Neuropeptides B/W receptor type 1 NPBWR1 Tchem GPCR -1.34565 19.5 151
Neuropeptides B/W receptor type 2 NPBWR2 Tbio GPCR -1.14202 8.84 57
Homer protein homolog 1 HOMER1 Tbio Non-IDG -2.39539 267.3 178
SLIT and NTRK-like protein 5 SLITRK5 Tbio Non-IDG -0.75000 6.92 84