Development Level

Tbio 92 | 11,178
Tchem 61 | 1,885
Tclin 44 | 612
Tdark 22 | 6,569

Collection

Ion Channel: IDG Consortium (T... 17 | 99
GPCR: IDG Consortium (Targets) 9 | 126
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

decreased total body fat amoun... 8 | 207
preweaning lethality, complete... 8 | 979
preweaning lethality, incomple... 7 | 499
abnormal behavior 6 | 298
abnormal embryo size 5 | 220
decreased grip strength 5 | 116
increased circulating chloride... 5 | 41
increased circulating sodium l... 5 | 71
decreased bone mineral content 4 | 151
decreased circulating HDL chol... 4 | 68
decreased fasted circulating g... 4 | 65
enlarged heart 4 | 210
hyperactivity 4 | 148
hypoactivity 4 | 132
impaired glucose tolerance 4 | 75
increased lean body mass 4 | 172
increased total body fat amoun... 4 | 134
abnormal heart morphology 3 | 162
decreased body weight 3 | 161
decreased circulating choleste... 3 | 93
decreased lean body mass 3 | 135
decreased vertical activity 3 | 208
impaired pupillary reflex 3 | 26
increased circulating triglyce... 3 | 42
increased startle reflex 3 | 112
tremors 3 | 39
abnormal bone structure 2 | 187
abnormal eye morphology 2 | 68
abnormal gait 2 | 69
abnormal head morphology 2 | 10
abnormal pericardium morpholog... 2 | 26
abnormal testis morphology 2 | 43
decreased circulating LDL chol... 2 | 38
decreased circulating alkaline... 2 | 46
decreased exploration in new e... 2 | 11
decreased neutrophil cell numb... 2 | 42
embryonic growth retardation 2 | 106
embryonic lethality prior to t... 2 | 278
improved glucose tolerance 2 | 79
increased bone mineral content 2 | 108
increased circulating iron lev... 2 | 30
increased mean corpuscular vol... 2 | 92
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
small testis 2 | 58
abnormal behavioral response t... 1 | 66
abnormal coat-hair pigmentatio... 1 | 64
abnormal craniofacial morpholo... 1 | 33
abnormal embryo turning 1 | 31
abnormal kidney morphology 1 | 65
abnormal liver morphology 1 | 17
abnormal locomotor behavior 1 | 24
abnormal lung morphology 1 | 26
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal startle reflex 1 | 15
abnormal tail length 1 | 3
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased anxiety-related resp... 1 | 12
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating creatine... 1 | 4
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased heart left ventricle... 1 | 28
decreased pulmonary respirator... 1 | 5
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged stomach 1 | 2
increased bone mineral density 1 | 72
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating aspartat... 1 | 15
increased circulating choleste... 1 | 66
increased circulating creatine... 1 | 5
increased circulating fructosa... 1 | 13
increased circulating serum al... 1 | 22
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
limb grasping 1 | 41
microphthalmia 1 | 26
pale yolk sac 1 | 25
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
small thymus 1 | 16
thin ventricular wall 1 | 24

Disease

Carcinoma 163 | 11,192
glioblastoma 115 | 5,635
medulloblastoma, large-cell 113 | 6,086
ependymoma 108 | 4,559
atypical teratoid / rhabdoid tumor 103 | 4,971
oligodendroglioma 98 | 2,768
Schizophrenia 92 | 1,136
adult high grade glioma 91 | 3,701
psoriasis 91 | 6,514
astrocytic glioma 81 | 2,530
group 3 medulloblastoma 80 | 4,002
primitive neuroectodermal tumor 80 | 2,957
Astrocytoma, Pilocytic 76 | 3,006
ovarian cancer 69 | 8,297
Kidney cancer 67 | 2,548
osteosarcoma 64 | 7,766
Bipolar Disorder 61 | 646
lung carcinoma 56 | 2,755
Epilepsy 53 | 775
subependymal giant cell astrocytoma 52 | 2,230
lung cancer 50 | 4,607
Depressive disorder 49 | 401
Pick disease 49 | 1,856
Alcoholic Intoxication, Chronic 47 | 283
Mental Depression 44 | 325
Breast cancer 40 | 3,469
malignant mesothelioma 38 | 3,135
Mood Disorders 37 | 181
Major Depressive Disorder 36 | 293
Parkinson's disease 33 | 378
pituitary cancer 33 | 1,915
Seizures 32 | 584
Alzheimer's disease 30 | 640
group 4 medulloblastoma 28 | 1,806
invasive ductal carcinoma 27 | 2,867
Autistic Disorder 26 | 358
Intellectual disability 26 | 998
Unipolar Depression 26 | 244
intraductal papillary-mucinous adenoma (IPMA) 26 | 2,872
Alcohol dependence 23 | 107
Cancer 23 | 2,388
Liver cancer 23 | 589
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,902
Obesity 21 | 655
Attention deficit hyperactivity disorder 20 | 272
Toxic encephalopathy 20 | 139
astrocytoma 20 | 1,113
colon cancer 20 | 1,428
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,204
Cocaine-Related Disorders 19 | 90
Cognitive delay 19 | 596
Global developmental delay 19 | 596
Mental and motor retardation 19 | 596
Pain agnosia 19 | 99
Substance Withdrawal Syndrome 19 | 53
interstitial cystitis 19 | 2,237
Neurodegenerative disease 18 | 402
adrenocortical carcinoma 18 | 1,385
Melanoma 17 | 689
Migraine 17 | 78
pediatric high grade glioma 17 | 1,035
Autosomal recessive predisposition 16 | 1,407
Muscle hypotonia 16 | 562
diabetes mellitus 16 | 1,683
Dementia 15 | 172
General anesthesia 15 | 53
medulloblastoma 15 | 702
non primary Sjogren syndrome sicca 15 | 861
Down syndrome 14 | 480
Dull intelligence 14 | 634
Huntington's disease 14 | 75
Hyperalgesia 14 | 80
Low intelligence 14 | 634
Mental Retardation 14 | 634
Mental deficiency 14 | 634
Pain 14 | 102
Poor school performance 14 | 634
ductal carcinoma in situ 14 | 1,686
Amyotrophic lateral sclerosis 13 | 437
Cerebellar Ataxia 13 | 302
Cocaine Dependence 13 | 51
Irritable bowel syndrome 13 | 57
Opiate dependence 13 | 29
Skin cancer 13 | 451
lung adenocarcinoma 13 | 2,627
Hypertension 12 | 372
Psychotic Disorders 12 | 150
Substance abuse 12 | 58
tuberculosis 12 | 1,963
Alcoholism 11 | 45
Gastroesophageal reflux disease 11 | 108
Infantile onset 11 | 236
Multiple Sclerosis 11 | 527
Neuropathy 11 | 254
Status Epilepticus 11 | 96
non-small cell lung cancer 11 | 2,799
obsessive-compulsive disorder 11 | 61
pancreatic cancer 11 | 2,322
Atopic dermatitis 10 | 915
cystic fibrosis 10 | 1,629

Tissue

Endocrine System 208 | 18,159
Nervous System 204 | 16,725
Female tissues 195 | 17,400
Digestive Tract 193 | 17,369
Skin and soft tissues 192 | 17,230
Male tissues 183 | 17,142
Blood and immune system 180 | 16,909
Liver and Pancreas 179 | 16,750
Urinary Tract 172 | 16,678
Respiratory system 168 | 16,393
Cardiovascular System 146 | 15,192

Target Family

Non-IDG 90 | 12,091
GPCR 52 | 408
Ion Channel 48 | 344
Enzyme 13 | 4,145
Transporter 12 | 473
Kinase 4 | 634

GO Process

chemical synaptic transmission 219 | 219
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Somatostatin receptor type 4 SSTR4 Tclin GPCR -1.72615 44.8 147
Acid-sensing ion channel 2 ASIC2 Tbio Ion Channel -2.49683 295.8 140
MYCBP-associated protein MYCBPAP Tbio Non-IDG 0.00000 37
Excitatory amino acid transporter 1 SLC1A3 Tchem Transporter -2.76402 569.7 221
5-hydroxytryptamine receptor 7 HTR7 Tclin GPCR -4.15964 13643.7 259
Excitatory amino acid transporter 2 SLC1A2 Tchem Transporter -2.96237 939.6 187
Probable G-protein coupled receptor 88 GPR88 Tchem GPCR -1.48157 29.6 150
5-hydroxytryptamine receptor 3B HTR3B Tchem Ion Channel -1.66753 42.0 91
Probable G-protein coupled receptor 149 GPR149 Tdark GPCR -0.54429 3.90 147
Putative pro-MCH-like protein 2 PMCHL2 Tdark Non-IDG 0.00000 0