Development Level

Tbio 41 | 11,445
Tchem 13 | 1,598
Tclin 6 | 613
Tdark 2 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 7 | 979
preweaning lethality, incomple... 5 | 499
embryonic lethality prior to t... 4 | 278
abnormal behavior 3 | 298
abnormal pericardium morpholog... 2 | 26
decreased caudal vertebrae num... 2 | 53
decreased circulating glucose ... 2 | 126
decreased vertical activity 2 | 208
hyperactivity 2 | 148
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
male infertility 2 | 123
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal embryo development 1 | 7
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal eye pigmentation 1 | 3
abnormal femur morphology 1 | 14
abnormal limb bud morphology 1 | 17
abnormal rib morphology 1 | 10
abnormal sleep behavior 1 | 70
absent pinna reflex 1 | 23
cardiovascular system phenotyp... 1 | 36
corneal opacity 1 | 32
corneal vascularization 1 | 6
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased prepulse inhibition 1 | 82
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic lethality prior to o... 1 | 239
female infertility 1 | 60
increased bone mineral content 1 | 108
increased cardiac muscle contr... 1 | 8
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased heart rate variabili... 1 | 7
increased lean body mass 1 | 172
increased prepulse inhibition 1 | 32
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
small heart 1 | 10
small kidney 1 | 16
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
thrombocytopenia 1 | 56

Disease

Carcinoma 45 | 11,493
osteosarcoma 41 | 7,950
ovarian cancer 41 | 8,520
glioblastoma 40 | 5,792
medulloblastoma, large-cell 40 | 6,241
psoriasis 38 | 6,694
atypical teratoid / rhabdoid tumor 33 | 5,112
ependymoma 31 | 4,679
lung cancer 29 | 4,740
adult high grade glioma 27 | 3,801
group 3 medulloblastoma 25 | 4,104
Breast cancer 22 | 3,578
Intellectual disability 22 | 1,016
oligodendroglioma 22 | 2,850
Astrocytoma, Pilocytic 20 | 3,081
Cancer 20 | 2,499
Kidney cancer 20 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,291
non-small cell lung cancer 19 | 2,890
primitive neuroectodermal tumor 19 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
Schizophrenia 17 | 1,160
invasive ductal carcinoma 17 | 2,951
lung adenocarcinoma 17 | 2,716
lung carcinoma 17 | 2,843
Pick disease 16 | 1,894
astrocytic glioma 16 | 2,597
Epilepsy 15 | 792
colon cancer 15 | 1,478
malignant mesothelioma 15 | 3,232
subependymal giant cell astrocytoma 15 | 2,287
Dull intelligence 14 | 645
Low intelligence 14 | 645
Mental Retardation 14 | 645
Mental deficiency 14 | 645
Poor school performance 14 | 645
ductal carcinoma in situ 14 | 1,745
Bipolar Disorder 13 | 666
Cognitive delay 13 | 608
Global developmental delay 13 | 608
Mental and motor retardation 13 | 608
group 4 medulloblastoma 13 | 1,855
pancreatic cancer 13 | 2,398
Seizures 11 | 596
adrenocortical carcinoma 11 | 1,428
diabetes mellitus 11 | 1,728
interstitial cystitis 11 | 2,312
Major Depressive Disorder 10 | 301
Unipolar Depression 10 | 250
astrocytoma 10 | 1,146
nasopharyngeal carcinoma 10 | 1,058
ulcerative colitis 10 | 1,819
Autosomal recessive predisposition 9 | 1,442
Obesity 9 | 678
Short stature 9 | 531
Skin cancer 9 | 469
Alzheimer's disease 8 | 658
Breast Neoplasms 8 | 445
Liver cancer 8 | 604
Melanoma 8 | 711
Microcephaly 8 | 166
Rheumatoid arthritis 8 | 1,191
breast carcinoma 8 | 1,638
cutaneous lupus erythematosus 8 | 1,057
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
pituitary cancer 8 | 1,972
tuberculosis 8 | 2,010
Alcoholic Intoxication, Chronic 7 | 289
Atopic dermatitis 7 | 952
Autistic Disorder 7 | 364
Endometrial cancer 7 | 311
Endometriosis 7 | 540
Mammary Neoplasms 7 | 425
Multiple myeloma 7 | 1,332
Orbital separation excessive 7 | 244
dermatomyositis 7 | 966
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Downward slant of palpebral fissure 6 | 158
Hypertension 6 | 396
Hypertensive disease 6 | 292
Lissencephaly 6 | 69
Low set ears 6 | 181
Mental Depression 6 | 333
Osteoporosis 6 | 363
Prostatic Neoplasms 6 | 495
Vascular disease 6 | 319
gastric carcinoma 6 | 807
primary pancreatic ductal adenocarcinoma 6 | 1,109
spina bifida 6 | 1,074
Cardiovascular Diseases 5 | 59
Depressive disorder 5 | 409
Down syndrome 5 | 499
Duchenne muscular dystrophy 5 | 601
Language Delay 5 | 112
Nystagmus 5 | 317
Small head 5 | 374
Speech impairment 5 | 112
acute myeloid leukemia 5 | 783
medulloblastoma 5 | 720
pediatric high grade glioma 5 | 1,064

Tissue

Digestive Tract 61 | 17,369
Endocrine System 61 | 18,159
Nervous System 61 | 16,725
Blood and immune system 60 | 16,909
Female tissues 60 | 17,400
Liver and Pancreas 60 | 16,750
Skin and soft tissues 60 | 17,230
Urinary Tract 60 | 16,678
Male tissues 59 | 17,142
Respiratory system 57 | 16,393
Cardiovascular System 54 | 15,192

Target Family

Non-IDG 39 | 12,091
Transcription Factor 7 | 1,400
Enzyme 6 | 4,145
Kinase 3 | 634
Transporter 3 | 473
Epigenetic 2 | 242
GPCR 1 | 408
Ion Channel 1 | 344

GO Process

cerebral cortex development 62 | 62
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bardet-Biedl syndrome 4 protein BBS4 Tbio Non-IDG -1.53435 31.5 200
Transforming acidic coiled-coil-containing protein 3 TACC3 Tbio Non-IDG -1.99617 101.2 222
Nuclear distribution protein nudE homolog 1 NDE1 Tbio Non-IDG -2.01711 96.0 192
Rho GTPase-activating protein 11B ARHGAP11B Tbio Enzyme -0.78084 6.06 23
Smoothened homolog SMO Tclin GPCR -1.17466 14.5 415
Bifunctional purine biosynthesis protein PURH ATIC Tchem Non-IDG -2.93014 835.0 246
Contactin-associated protein-like 2 CNTNAP2 Tbio Non-IDG -2.36156 228.4 191
Centrosomal protein of 120 kDa CEP120 Tbio Non-IDG -0.93215 7.32 49
Pre-mRNA-splicing factor SYF1 XAB2 Tbio Non-IDG -1.02890 12.5 247
Achaete-scute homolog 1 ASCL1 Tbio Transcription Factor -2.44791 277.6 405