Development Level

Tbio 2 | 11,651

Disease

Cancer 2 | 2,499
Muscle hypotonia 2 | 571
lung cancer 2 | 4,740
Acute Lung Injury 1 | 22
Adenoma 1 | 167
Anxiety 1 | 136
Anxiety disease 1 | 113
Astrocytoma, Pilocytic 1 | 3,081
Autonomic dysregulation 1 | 6
Autonomic nervous system disorders 1 | 19
Benign Hereditary Chorea 1 | 2
Body Temperature Changes 1 | 10
Breathing dysregulation 1 | 3
Cardiovascular Abnormalities 1 | 31
Cardiovascular Diseases 1 | 59
Central hypoventilation 1 | 8
Chorea 1 | 29
Choreatic disease 1 | 52
Choreoathetoid movements 1 | 32
Choreoathetosis 1 | 32
Choreoathetosis, Hypothyroidism, And Neonatal Respiratory Distress 1 | 1
Chromosome 14q11-q22 deletion syndrome 1 | 3
Compensated hypothyroidism 1 | 5
Congenital central hypoventilation 1 | 6
Congenital central hypoventilation syndrome 1 | 18
Congenital diaphragmatic hernia 1 | 67
Congenital hypothyroidism 1 | 26
Constipation 1 | 181
Death in early childhood 1 | 82
Death in infancy 1 | 82
Diaphragmatic Hernia 1 | 40
Difficulty walking 1 | 28
Downward slant of palpebral fissure 1 | 158
Dysarthria 1 | 192
Dysautonomia 1 | 20
Dyschezia 1 | 135
Dyskinetic cerebral palsy 1 | 5
Dystonia 1 | 164
Dystonic disease 1 | 106
Epilepsy 1 | 792
Failure to gain weight 1 | 365
Familial hemophagocytic lymphohistiocytosis 3 1 | 5
Fetal valproate syndrome 1 | 4
Ganglioneuroblastoma 1 | 11
Ganglioneuroma 1 | 13
Gastroesophageal reflux disease 1 | 110
Goiter 1 | 38
Haddad syndrome 1 | 3
Heartburn 1 | 78
Hemangioma 1 | 69
Hernia, Diaphragmatic 1 | 40
Highly variable clinical phenotype 1 | 150
Highly variable phenotype and severity 1 | 150
Highly variable phenotype, even within families 1 | 150
Hirschsprung Disease 1 | 31
Hirschsprung's disease 1 | 46
Hyperhidrosis disorder 1 | 81
Hypothyroidism 1 | 122
Increased sweating 1 | 81
Low Birth Weights 1 | 69
Lung disease 1 | 142
Lung diseases 1 | 50
Megacolon 1 | 29
Motor delay 1 | 147
Mouth Abnormalities 1 | 14
Nervous System Diseases 1 | 53
No development of motor milestones 1 | 147
Oxyphilic adenoma 1 | 22
Papillary adenoma 1 | 4
Papillary thyroid carcinoma 1 | 43
Pediatric failure to thrive 1 | 365
Phenotypic variability 1 | 150
Pitt-Hopkins syndrome 1 | 20
Poor temperature regulation 1 | 10
Posteriorly rotated ear 1 | 61
Prenatal onset 1 | 139
Raised TSH level 1 | 8
Recurrent respiratory infections 1 | 141
Respiratory Distress Syndrome 1 | 15
Respiratory distress 1 | 43
Seizures 1 | 596
Sleep Apnea, Central 1 | 8
Small Cell Lung Carcinoma 1 | 41
Small cell carcinoma of lung 1 | 45
Small for gestational age (disorder) 1 | 69
Strabismus 1 | 270
Sweating 1 | 81
Thyroid Cancer, Nonmedullary, 1 1 | 2
Thyroid cancer, papillary 1 | 14
astrocytic glioma 1 | 2,597
atypical teratoid/rhabdoid tumor 1 | 357
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
nervous system disorder 1 | 53
non-small cell lung cancer 1 | 2,890
non-small cell lung cancer and chronic obstructive pulmonary disease 1 | 8
oligodendroglioma 1 | 2,850
ovarian cancer 1 | 8,520
pediatric high grade glioma 1 | 1,064
pituitary cancer 1 | 1,972
subependymal giant cell astrocytoma 1 | 2,287

Tissue

Blood and immune system 2 | 16,909
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Cardiovascular System 1 | 15,192
Female tissues 1 | 17,400
Liver and Pancreas 1 | 16,750
Male tissues 1 | 17,142
Nervous System 1 | 16,725
Urinary Tract 1 | 16,678

Target Family

Transcription Factor 2 | 1,400

GO Process

cerebral cortex GABAergic inte... 2 | 2
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Achaete-scute homolog 1 ASCL1 Tbio Transcription Factor -2.44791 277.6 405
Homeobox protein Nkx-2.1 NKX2-1 Tbio Transcription Factor -3.08631 1272.5 530