Development Level

Tbio 25 | 11,445
Tclin 9 | 613
Tchem 8 | 1,598

IMPC Phenotype

preweaning lethality, complete... 5 | 979
decreased vertical activity 3 | 208
increased bone mineral content 3 | 108
abnormal behavior 2 | 298
decreased neutrophil cell numb... 2 | 42
abnormal bone structure 1 | 187
abnormal eye morphology 1 | 68
abnormal seminal vesicle morph... 1 | 114
absent prostate gland 1 | 1
absent seminal vesicle 1 | 4
absent testes 1 | 6
decreased bone mineral content 1 | 151
decreased circulating alkaline... 1 | 46
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148
hypoactivity 1 | 132
increased blood urea nitrogen ... 1 | 48
increased bone mineral density 1 | 72
increased circulating triglyce... 1 | 42
increased lean body mass 1 | 172
prenatal lethality 1 | 28

Disease

Carcinoma 30 | 11,493
glioblastoma 24 | 5,792
medulloblastoma, large-cell 24 | 6,241
adult high grade glioma 21 | 3,801
osteosarcoma 21 | 7,950
ovarian cancer 21 | 8,520
atypical teratoid / rhabdoid tumor 18 | 5,112
psoriasis 18 | 6,694
lung cancer 17 | 4,740
group 3 medulloblastoma 15 | 4,104
subependymal giant cell astrocytoma 14 | 2,287
ependymoma 13 | 4,679
oligodendroglioma 13 | 2,850
primitive neuroectodermal tumor 12 | 3,035
Cancer 11 | 2,499
Kidney cancer 11 | 2,613
Schizophrenia 11 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
malignant mesothelioma 11 | 3,232
Astrocytoma, Pilocytic 10 | 3,081
Breast cancer 10 | 3,578
astrocytic glioma 10 | 2,597
colon cancer 10 | 1,478
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
Pick disease 8 | 1,894
astrocytoma 8 | 1,146
lung adenocarcinoma 8 | 2,716
lung carcinoma 8 | 2,843
group 4 medulloblastoma 7 | 1,855
interstitial cystitis 7 | 2,312
invasive ductal carcinoma 7 | 2,951
pancreatic cancer 7 | 2,398
pituitary cancer 7 | 1,972
Autosomal recessive predisposition 6 | 1,442
Epilepsy 6 | 792
cystic fibrosis 6 | 1,696
diabetes mellitus 6 | 1,728
non-small cell lung cancer 6 | 2,890
ulcerative colitis 6 | 1,819
Seizures 5 | 596
breast carcinoma 5 | 1,638
cutaneous lupus erythematosus 5 | 1,057
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
tuberculosis 5 | 2,010
Anxiety 4 | 136
Anxiety disease 4 | 113
Autistic Disorder 4 | 364
Blepharoptosis 4 | 231
Cerebellar Ataxia 4 | 304
Cerebellar hypoplasia and atrophy 4 | 41
Depressive disorder 4 | 409
Diabetes Mellitus, Non-Insulin-Dependent 4 | 145
Muscle hypotonia 4 | 571
Optic Atrophy 4 | 242
Parkinson's disease 4 | 392
Rheumatoid arthritis 4 | 1,191
Short stature 4 | 531
Status Epilepticus 4 | 98
nasopharyngeal carcinoma 4 | 1,058
non primary Sjogren syndrome sicca 4 | 891
Acromegaly 3 | 51
Adenoma 3 | 167
Alzheimer's disease 3 | 658
Arthritis, Rheumatoid 3 | 174
Atopic dermatitis 3 | 952
Bipolar Disorder 3 | 666
Carcinoid syndrome 3 | 5
Cerebral atrophy 3 | 178
Developmental regression 3 | 95
Diarrhea from Pancreatic VIPoma 3 | 5
Down syndrome 3 | 499
Hypercortisolism 3 | 8
Hyperreflexia 3 | 209
Liver cancer 3 | 604
Loss of developmental milestones 3 | 95
Malaria 3 | 160
Mental deterioration in childhood 3 | 95
Multiple Sclerosis 3 | 540
Multiple myeloma 3 | 1,332
Muscle Spasticity 3 | 195
Myopathy 3 | 185
Neurodevelopmental regression 3 | 95
Neuroendocrine Tumors 3 | 11
Pancreatic Neoplasm 3 | 85
Pancreatic Neoplasms 3 | 85
Pituitary adenoma 3 | 38
Prostatic Neoplasms 3 | 495
Psychomotor regression 3 | 95
Psychomotor regression beginning in infancy 3 | 95
Psychomotor regression in infants 3 | 95
Psychomotor regression, progressive 3 | 95
active Crohn's disease 3 | 922
atypical teratoid/rhabdoid tumor 3 | 357
chronic rhinosinusitis 3 | 512
ductal carcinoma in situ 3 | 1,745
fibroadenoma 3 | 559
gastric carcinoma 3 | 807
pediatric high grade glioma 3 | 1,064
progressive supranuclear palsy 3 | 676

Tissue

Endocrine System 42 | 18,159
Female tissues 41 | 17,400
Digestive Tract 40 | 17,369
Skin and soft tissues 40 | 17,230
Liver and Pancreas 39 | 16,750
Nervous System 39 | 16,725
Blood and immune system 37 | 16,909
Male tissues 37 | 17,142
Urinary Tract 36 | 16,678
Cardiovascular System 34 | 15,192
Respiratory system 34 | 16,393

Target Family

Non-IDG 17 | 12,091
Transcription Factor 9 | 1,400
Enzyme 7 | 4,145
GPCR 4 | 408
Ion Channel 2 | 344
Kinase 2 | 634
Epigenetic 1 | 242

GO Process

cerebellum development 42 | 42
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Polypyrimidine tract-binding protein 2 PTBP2 Tbio Non-IDG -2.05261 113.3 151
Somatostatin receptor type 1 SSTR1 Tclin GPCR -2.14265 126.2 303
Somatostatin receptor type 2 SSTR2 Tclin GPCR -2.53936 363.5 246
Bifunctional purine biosynthesis protein PURH ATIC Tchem Non-IDG -2.93014 835.0 246
Contactin-1 CNTN1 Tbio Non-IDG -1.93017 87.6 211
Protein lifeguard 2 FAIM2 Tbio Non-IDG -2.37264 234.7 176
Unconventional myosin-XVI MYO16 Tbio Non-IDG -0.83369 6.89 43
Somatostatin receptor type 3 SSTR3 Tclin GPCR -1.89900 68.6 106
Protein JBTS17 C5orf42 Tbio Non-IDG -2.19760 152.8 9
Attractin ATRN Tbio Non-IDG -2.61000 386.6 172