Development Level

Tbio 14 | 11,445
Tchem 3 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

decreased body weight 1 | 161
decreased lean body mass 1 | 135
decreased total body fat amoun... 1 | 207
increased circulating bilirubi... 1 | 16
increased mean corpuscular hem... 1 | 96
thrombocytosis 1 | 27

Disease

Carcinoma 18 | 11,493
osteosarcoma 13 | 7,950
ovarian cancer 13 | 8,520
Kidney cancer 11 | 2,613
atypical teratoid / rhabdoid tumor 9 | 5,112
glioblastoma 9 | 5,792
medulloblastoma, large-cell 9 | 6,241
psoriasis 9 | 6,694
group 3 medulloblastoma 8 | 4,104
malignant mesothelioma 8 | 3,232
Microcephaly 6 | 166
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
primitive neuroectodermal tumor 6 | 3,035
Autosomal recessive predisposition 5 | 1,442
Cognitive delay 5 | 608
Global developmental delay 5 | 608
Intellectual disability 5 | 1,016
Mental and motor retardation 5 | 608
Pick disease 5 | 1,894
Short stature 5 | 531
Small head 5 | 374
adult high grade glioma 5 | 3,801
lung cancer 5 | 4,740
Breast cancer 4 | 3,578
Cancer 4 | 2,499
Dull intelligence 4 | 645
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Poor school performance 4 | 645
Sloping forehead 4 | 46
colon cancer 4 | 1,478
progressive supranuclear palsy 4 | 676
Agenesis of corpus callosum 3 | 83
Dilated ventricles (finding) 3 | 121
Hyperreflexia 3 | 209
MICROCEPHALY, PRIMARY AUTOSOMAL RECESSIVE, 1 3 | 16
Pachygyria 3 | 41
Severe mental retardation (I.Q. 20-34) 3 | 99
adrenocortical carcinoma 3 | 1,428
ductal carcinoma in situ 3 | 1,745
ependymoma 3 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
invasive ductal carcinoma 3 | 2,951
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
pituitary cancer 3 | 1,972
posterior fossa group A ependymoma 3 | 468
subependymal giant cell astrocytoma 3 | 2,287
Abnormal cortical bone morphology 2 | 22
Acquired scoliosis 2 | 281
Astrocytoma, Pilocytic 2 | 3,081
Atopic dermatitis 2 | 952
Bipolar Disorder 2 | 666
Chronic obstructive pulmonary disease 2 | 184
Convex nasal bridge 2 | 57
Cortical gyral simplification 2 | 19
Curvature of spine 2 | 282
Ectopic Tissue 2 | 14
Epilepsy 2 | 792
Fetal Growth Retardation 2 | 189
Frontal lobe hypoplasia 2 | 9
Glaucoma 2 | 239
Infant, Small for Gestational Age 2 | 176
Intrauterine retardation 2 | 176
MICROCEPHALY AND CHORIORETINOPATHY, AUTOSOMAL RECESSIVE, 1 2 | 2
Microcephaly with chorioretinopathy, autosomal recessive 2 | 3
Prenatal onset 2 | 139
Prominent nasal bridge 2 | 57
Prostate cancer 2 | 175
Schizophrenia 2 | 1,160
Seckel syndrome 2 | 34
Seizures 2 | 596
Thin upper lip vermilion 2 | 67
Unilateral agenesis of kidney 2 | 20
Upward slant of palpebral fissure 2 | 75
Vesico-Ureteral Reflux 2 | 33
active Crohn's disease 2 | 922
astrocytic glioma 2 | 2,597
breast carcinoma 2 | 1,638
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
medulloblastoma 2 | 720
tuberculosis and treatment for 6 months 2 | 409
Brain cancer 1 | 30
Cerebral Ischemia 1 | 37
Defective tooth enamel 1 | 31
Dystrophic tooth enamel 1 | 31
Enamel abnormalities 1 | 31
Lobular neoplasia 1 | 15
Narrow face 1 | 54
Premature Menopause 1 | 31
Premature ovarian failure 1 | 65
Reduced number of teeth 1 | 21
Reduced visual acuity 1 | 63
Sandal gap 1 | 24
Sparse scalp hair 1 | 42
Thin face 1 | 54
Townes-Brocks syndrome 1 | 15

Tissue

Blood and immune system 19 | 16,909
Cardiovascular System 19 | 15,192
Digestive Tract 19 | 17,369
Endocrine System 19 | 18,159
Female tissues 19 | 17,400
Liver and Pancreas 19 | 16,750
Male tissues 19 | 17,142
Nervous System 19 | 16,725
Respiratory system 19 | 16,393
Skin and soft tissues 19 | 17,230
Urinary Tract 19 | 16,678

Target Family

Non-IDG 14 | 12,091
Kinase 3 | 634
Enzyme 1 | 4,145
Ion Channel 1 | 344

GO Process

centrosome duplication 19 | 19
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Polycystin-2 PKD2 Tchem Ion Channel -2.63806 461.3 231
Nuclear distribution protein nudE homolog 1 NDE1 Tbio Non-IDG -2.01711 96.0 192
Gamma-tubulin complex component 6 TUBGCP6 Tbio Non-IDG -0.76777 4.81 83
Centrosomal protein of 152 kDa CEP152 Tbio Non-IDG -1.23896 18.1 117
Breast cancer type 2 susceptibility protein BRCA2 Tbio Non-IDG -3.46139 2647.6 209
Centrosomal protein of 192 kDa CEP192 Tbio Non-IDG -1.15560 13.3 34
SCL-interrupting locus protein STIL Tbio Non-IDG -1.99386 94.6 49
Serine/threonine-protein kinase BRSK1 BRSK1 Tchem Kinase -1.44039 28.9 301
Cytoskeleton-associated protein 5 CKAP5 Tbio Non-IDG -2.12618 129.3 77
Centriolar coiled-coil protein of 110 kDa CCP110 Tbio Non-IDG -1.45267 26.4 109