Development Level

Tbio 10 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

decreased startle reflex 2 | 75
abnormal behavior 1 | 298
abnormal cornea morphology 1 | 31
abnormal gait 1 | 69
abnormal sleep behavior 1 | 70
convulsive seizures 1 | 13
corneal opacity 1 | 32
decreased basophil cell number 1 | 16
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased coping response 1 | 8
decreased grip strength 1 | 116
decreased leukocyte cell numbe... 1 | 73
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
hyperactivity 1 | 148
hypoactivity 1 | 132
increased fasted circulating g... 1 | 76
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
limb grasping 1 | 41
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 9 | 11,493
medulloblastoma, large-cell 9 | 6,241
group 3 medulloblastoma 8 | 4,104
oligodendroglioma 8 | 2,850
atypical teratoid / rhabdoid tumor 7 | 5,112
ependymoma 7 | 4,679
Muscle hypotonia 6 | 571
glioblastoma 6 | 5,792
psoriasis 6 | 6,694
subependymal giant cell astrocytoma 6 | 2,287
Astrocytoma, Pilocytic 5 | 3,081
Cognitive delay 5 | 608
Down syndrome 5 | 499
Global developmental delay 5 | 608
Mental and motor retardation 5 | 608
Autosomal recessive predisposition 4 | 1,442
Dull intelligence 4 | 645
Epilepsy 4 | 792
Intellectual disability 4 | 1,016
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Nystagmus 4 | 317
Pick disease 4 | 1,894
Poor school performance 4 | 645
Schizophrenia 4 | 1,160
Seizures 4 | 596
adult high grade glioma 4 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
osteosarcoma 4 | 7,950
ovarian cancer 4 | 8,520
pediatric high grade glioma 4 | 1,064
Atopic dermatitis 3 | 952
Breast cancer 3 | 3,578
Cerebellar Ataxia 3 | 304
Delayed speech and language development 3 | 112
Language Delay 3 | 112
Leukodystrophy 3 | 55
Multiple Sclerosis 3 | 540
Neurodegenerative disease 3 | 414
Neuropathy 3 | 261
Optic Atrophy 3 | 242
Paraparesis, Spastic 3 | 16
Speech Delay 3 | 112
Speech impairment 3 | 112
active ulcerative colitis 3 | 764
astrocytic glioma 3 | 2,597
astrocytoma 3 | 1,146
breast carcinoma 3 | 1,638
cutaneous lupus erythematosus 3 | 1,057
ductal carcinoma in situ 3 | 1,745
glioblastoma multiforme 3 | 142
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
non-small cell lung cancer 3 | 2,890
primitive neuroectodermal tumor 3 | 3,035
progressive supranuclear palsy 3 | 676
Absent reflex 2 | 92
Absent tendon reflex 2 | 92
Babinski Reflex 2 | 100
Cancer 2 | 2,499
Cerebellar Dysmetria 2 | 56
Congenital deafness 2 | 185
Congenital pes cavus 2 | 88
Deafness 2 | 198
Deglutition Disorders 2 | 132
Dysmyelination of the brain 2 | 6
Electroencephalogram abnormal 2 | 101
Failure to gain weight 2 | 365
Generalized seizures 2 | 9
Generalized seizures, recurrent 2 | 9
Hearing Loss, Partial 2 | 185
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Infantile onset 2 | 238
Kidney cancer 2 | 2,613
Muscle Spasticity 2 | 195
Pediatric failure to thrive 2 | 365
Phenotypic variability 2 | 150
Pyramidal sign 2 | 29
Reflex, Deep Tendon, Absent 2 | 92
Sensorineural Hearing Loss (disorder) 2 | 284
Sensorineural hearing loss 2 | 106
Small head 2 | 374
Tremor 2 | 113
White matter dysmyelination/demyelination 2 | 6
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
group 4 medulloblastoma 2 | 1,855
hearing impairment 2 | 199
hereditary spastic paraplegia 2 | 318
interstitial cystitis 2 | 2,312
lung cancer 2 | 4,740
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
pituitary cancer 2 | 1,972
EAST syndrome 1 | 5

Tissue

Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Nervous System 11 | 16,725
Blood and immune system 10 | 16,909
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Skin and soft tissues 10 | 17,230
Urinary Tract 9 | 16,678
Respiratory system 8 | 16,393
Cardiovascular System 7 | 15,192

Target Family

Transcription Factor 5 | 1,400
Non-IDG 4 | 12,091
Enzyme 1 | 4,145
Ion Channel 1 | 344

GO Process

central nervous system myelina... 11 | 11
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcription factor HES-5 HES5 Tbio Transcription Factor -2.08501 97.6 139
DNA-binding protein inhibitor ID-4 ID4 Tbio Transcription Factor -2.22096 177.3 245
Contactin-2 CNTN2 Tbio Non-IDG -2.59791 404.0 198
Transcription factor SOX-10 SOX10 Tbio Transcription Factor -2.69195 478.2 389
Myelin regulatory factor MYRF Tbio Transcription Factor -2.68286 462.0 31
Homeobox protein Nkx-6.2 NKX6-2 Tbio Transcription Factor -2.51005 319.0 66
ATP-sensitive inward rectifier potassium channel 10 KCNJ10 Tbio Ion Channel -2.43730 273.3 158
Myelin proteolipid protein PLP1 Tbio Non-IDG -2.78813 591.1 191
Aspartoacylase ASPA Tbio Enzyme -2.04271 107.1 151
Contactin-associated protein 1 CNTNAP1 Tbio Non-IDG -1.99192 94.4 125